Boston College Eagles vs. Louisville Cardinals Picks, Prediction, Odds and Line Movement for Saturday, January 10, 2026

By: Chris King Published 01/10/2026, 06:02 AM ET
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It’s a conference tilt between foes from the ACC on the hardwood in the Bluegrass State as the Boston College Eagles take on the #20 Louisville Cardinals Saturday afternoon and we have you covered with our Boston College vs. Louisville prediction. Boston College fell 79-71 to NC State at home in their previous contest Tuesday, covering the line as a 12.5-point underdog. Louisville fell 84-73 at home to #6 Duke in their previous contest Wednesday, failing to cover the line as a 1.5-point underdog. In the all-time series between the teams, the Cardinals own an 11-8 advantage, including an 84-58 road win in the most recent matchup February 5, 2025. Read more about this Boston College vs. Louisville prediction! Struggling with handicapping? Try our NCAAB Predictions!

Boston College Seeking to Pick Up Road Conference Win

Boston College dropped their second straight game as they were dropped at home by NC State in their previous game. The Eagles fell to 7-8 overall and are tied for the basement of the ACC with a 0-2 mark in conference play. Against NC State, Boston College’s lone lead in the game came when they scored the game’s opening bucket. The Eagles were quickly down double digits as they were down 23-10 with 10:16 to play in the first half and played from behind from there. Boston College trailed 40-32 at the half and didn’t get closer than three the rest of the way to wind up with the loss. The Eagles shot 51.1% from the field, including nine of 18 from three-point range, but turned the ball over 16 times in the contest. Fred Payne led Boston College with 24 points in the win.

The Eagles come into this contest 320th in scoring offense with an average of 69.5 points per game. Boston College is an above average team in the rebounding department as they are pulling down 39.1 rebounds per game while ranking 347th by dishing out 11.1 assists per contest. The Eagles are 53rd in scoring defense as they give up an average of 67.4 points per game. Donald Hand Jr. leads the team with 15.5 points plus 5.3 rebounds per game so far this season. Fred Payne (13.2 points, 3.6 rebounds) and Boden Kapke (8.9 points, 5.5 rebounds) are secondary scoring options. Chase Forte, Jayden Hastings, Luka Toews, Aidan Shaw, Caleb Steger, Jason Asemota and Marko Radunovic are important pieces for the Boston College rotation. Boston College shoots 40% from the field as a team on the year, which leaves them 351st in Division I. The Eagles are knocking down 7.6 triples a night while shooting 28.9% from beyond the arc. Boston College has been mediocre at the free throw line, sinking 68.3% of their attempts, putting them 296th in the nation.

Key Injury Report for Boston College:

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  • Forward Jason Asemota (undisclosed) is questionable.

Cardinals Hoping to Get Back on Track

Louisville lost their second straight game as they were dumped by #6 Duke at home in their previous contest Tuesday night. The Cardinals fell to 11-4 overall on the year and look to even their mark in conference play as they are 1-2. Against Duke, Louisville controlled the game in the first half, leading by as many as 12, and settling for a nine-point lead at intermission. The Cardinals gave up an 18-6 run to start the second half to trail 56-53 with 12:18 remaining and never got even again. Louisville shot 40% from the field, including 12 of 38 from three-point range, and lost the points in the paint battle by a 40-26 margin. Ryan Conwell led the Cardinals with 24 points and seven rebounds in the loss.

The Cardinals enter the game 21st in scoring offense with 89.2 points per contest this season. Louisville is 19th in the nation in rebounding with 42 per contest while the team is 29th in Division I by dishing out 18.1 assists per contest. The Cardinals are above average defensively, ranking 100th in scoring defense as they allow an average of 70.1 points per game this year. Mikel Brown Jr. is second on the team with 16.6 points plus 5.1 assists per game this season. Ryan Conwell (19.9 points, 4.9 rebounds), Khani Rooths (6.3 points, 4.5 rebounds) and Isaac McKneely (11.3 points, 3.1 rebounds) are good secondary options offensively. J’Vonne Hadley (10.1 points, 5.4 rebounds), Sananda Fru (10.5 points, 6.7 rebounds), Adrian Woolley (10 points, 4.5 rebounds), Kobe Rodgers, Vangelis Zougres, Kasean Pryor and Aly Khalifa are other contributors for coach Pat Kelsey. Louisville shoots 46.6% from the floor as a team this season. The Cardinals are splashing 12.2 triples a night (4th) while shooting 35.1% from beyond the arc. Louisville has been above average at the charity stripe in their attempts by cashing in 77.4% of their attempts this season, which is 25th in Division I.

Key Injury Report for Louisville:

  • Guard Mikel Brown (back) is questionable.

Boston College vs. Louisville Pick

Boston College vs. Louisville Spread Pick

  • Louisville (4 units)

Louisville has sputtered a bit of late with three losses in their last five games but they should get a break here. The Cardinals are 8-1 at home with their lone loss coming against Duke in a game they controlled for the first 20 minutes of play. Meanwhile, Boston College is just 1-2 on the road with their lone win coming over Temple. The Eagles struggle offensively and will be tested trying to keep up with a Louisville team that can bury teams from the perimeter. Boston College’s inefficiency offensively, coupled with the Cardinals’ advantage offensively, carries them to a home win here.

Boston College vs. Louisville Over/Under Pick

  • Under 143.5 (4 units)

Boston College has seen the under post a 9-6 mark in their 15 games this season. The Eagles have been average offensively, ranking 275th in offensive efficiency, 318th in effective field goal percentage (46.4%), 307th in two-point shooting (48.9%) and 348th in three-point shooting (28.9%) this season. The Eagles are slightly below average in terms of pace as they are 303rd in tempo with 65.9 possessions a night. Louisville has seen the under post an 8-7 mark in their 15 games on the year. The Cardinals are sixth in offensive efficiency, 36th in effective field goal percentage (56.3%), 100th in turnover percentage (16%), 55th in offensive rebounding percentage (35.7%) and 18th in two-point shooting (60.7%) on the year. Louisville is 59th in tempo with 71 possessions a night. Look for this game to wind up falling under the total.

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