Charlotte vs. Appalachian State, Picks and Prediction, Friday, November 21, 2025

By: Bosun Akinpelu Published 11/20/2025, 09:37 PM ET
Use Code WWWC

Charlotte (2-2, 0-0 American) will be trying to pick up their first road win of the season when they visit Holmes Convocation Center on Friday night to face Appalachian State (3-2, 0-0 Sun Belt) at 6:30 PM. ET. Read on to find out which team picks up the win in this 49ers vs. Mountaineers prediction. Struggling with handicapping? Try our NCAAB Predictions!

The 49ers are coming off an 84-76 loss to Virginia Tech as 18.5-point underdogs. The Mountaineers are coming off an 85-77 win over Dartmouth as 1.5-point favorites.

Charlotte is 7-3 in its last 10 games against Appalachian State. The 49ers won the last meeting in 2022, 71-62.

Charlotte Trying To Snap Two-Game Losing Streak

The 49ers followed up their two-game winning streak to start the season with two straight losses. They will try to snap their losing streak and pick up their first road win of the season when they play on Friday.

Get Free $30 Credit for Premium Picks + Exclusive Discounts

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Winners and Whiners may use third-party services to process my data.

Charlotte averages 73.3 points per game. They’ve made 44 percent of their field goals and 38.4 percent of their three-pointers.

Ben Bradford leads the team with 16.5 points and three rebounds per game. Kuluei Mading averages 12 points per game, while Anton Bonke averages 12 points and 10.5 rebounds per game.

Charlotte is giving up 71.8 points per game. Opponents have made 45 percent of their field goals and 36 percent of their three-pointers.

Injuries: Jame Elouna Eyenga (Wrist) is questionable for this game.

Appalachian State Going For Second Consecutive Win

The Mountaineers bounced back from their loss to Ohio State with a win over Dartmouth in their last game. They will try to keep the momentum going and pick up their fourth win in their last five games when they play on Friday.

Appalachian State averages 74.4 points per game. They’ve made 44.3 percent of their field goals and 31 percent of their three-pointers.

Kasen Jennings leads the Mountaineers with 17.8 points and 2.8 rebounds per game. Luke Wilson averages 9.8 points and 5.8 rebounds per game, while Eren Banks averages 9.4 points and 3.6 rebounds per game.

Appalachian State is giving up 66.8 points per game. Opponents have made 42 percent of their field goals and 36 percent of their three-pointers against them.

Injuries: KJ Vasser (Foot) is questionable for this game.

Charlotte vs. Appalachian State Picks

Point Spread Pick for Charlotte vs. Appalachian State

  • Appalachian State Mountaineers to cover. (4 Units)

The Mountaineers have won three of their last four games, while the 49ers have lost three of their last four games. Appalachian State has the edge here because they’re playing well offensively, scoring more than 74 points per game. They’ve also done a better job at the charity stripe, making over 72 percent of their free throws at home, while the 49ers make less than 65 percent of theirs. They rebound the ball well and grab more than 10 offensive rebounds per game, which will give them more scoring chances. They also do a good job of protecting the ball and won’t give up many easy-scoring chances. The 49ers aren’t very good defensively, and they’re giving up more than 80 points per game on the road, so expect them to have a hard time slowing down the Mountaineers. Take Appalachian State to cover the spread.

Over/Under Pick for Charlotte vs. Appalachian State

  • Over (4 Units)

The 49ers average 73.3 points per game. They play at the 347th-fastest pace in the nation, averaging 67.2 possessions per game, and they’re facing a team that is giving up 66.8 points per game. The Mountaineers average 74.4 points per game. They play at the 354th-fastest pace in the nation, averaging 66.5 possessions per game, and they’re facing a team that is giving up 84 points per game on the road. Expect these teams to score enough points to push the score over the total. The 49ers and Mountaineers played over the total in their last two meetings.

Betting on College Basketball?

BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $200 in Bonuses Instantly!

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Odds Requirements -500
Cashable No

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.