Charlotte vs. Appalachian State, Picks and Prediction, Friday, November 21, 2025
Charlotte (2-2, 0-0 American) will be trying to pick up their first road win of the season when they visit Holmes Convocation Center on Friday night to face Appalachian State (3-2, 0-0 Sun Belt) at 6:30 PM. ET. Read on to find out which team picks up the win in this 49ers vs. Mountaineers prediction. Struggling with handicapping? Try our NCAAB Predictions!
The 49ers are coming off an 84-76 loss to Virginia Tech as 18.5-point underdogs. The Mountaineers are coming off an 85-77 win over Dartmouth as 1.5-point favorites.
Charlotte is 7-3 in its last 10 games against Appalachian State. The 49ers won the last meeting in 2022, 71-62.
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Charlotte Trying To Snap Two-Game Losing Streak
The 49ers followed up their two-game winning streak to start the season with two straight losses. They will try to snap their losing streak and pick up their first road win of the season when they play on Friday.
Charlotte averages 73.3 points per game. They’ve made 44 percent of their field goals and 38.4 percent of their three-pointers.
Ben Bradford leads the team with 16.5 points and three rebounds per game. Kuluei Mading averages 12 points per game, while Anton Bonke averages 12 points and 10.5 rebounds per game.
Charlotte is giving up 71.8 points per game. Opponents have made 45 percent of their field goals and 36 percent of their three-pointers.
Injuries: Jame Elouna Eyenga (Wrist) is questionable for this game.
Appalachian State Going For Second Consecutive Win
The Mountaineers bounced back from their loss to Ohio State with a win over Dartmouth in their last game. They will try to keep the momentum going and pick up their fourth win in their last five games when they play on Friday.
| # | Handicapper | Profit |
|---|---|---|
| 1 |  David Hess | +1,311.00 |
| 2 |  Ben Burns | +1,082.00 |
| 3 |  Joe Duffy | +572.00 |
| 4 |  Tony Karpinski | +333.00 |
| 5 |  Dan Kaiser | +256.00 |
Appalachian State averages 74.4 points per game. They’ve made 44.3 percent of their field goals and 31 percent of their three-pointers.
Kasen Jennings leads the Mountaineers with 17.8 points and 2.8 rebounds per game. Luke Wilson averages 9.8 points and 5.8 rebounds per game, while Eren Banks averages 9.4 points and 3.6 rebounds per game.
Appalachian State is giving up 66.8 points per game. Opponents have made 42 percent of their field goals and 36 percent of their three-pointers against them.
Injuries: KJ Vasser (Foot) is questionable for this game.
Charlotte vs. Appalachian State Picks
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Rob Vincilleti | +1,778.00 |
| 2 |  Ross Benjamin | +1,716.00 |
| 3 | David Hess | +1,326.00 |
| 4 |  Earle Sports Bets | +1,323.00 |
| 5 | Dan Kaiser | +1,071.00 |
Point Spread Pick for Charlotte vs. Appalachian State
- Appalachian State Mountaineers to cover. (4 Units)
The Mountaineers have won three of their last four games, while the 49ers have lost three of their last four games. Appalachian State has the edge here because they’re playing well offensively, scoring more than 74 points per game. They’ve also done a better job at the charity stripe, making over 72 percent of their free throws at home, while the 49ers make less than 65 percent of theirs. They rebound the ball well and grab more than 10 offensive rebounds per game, which will give them more scoring chances. They also do a good job of protecting the ball and won’t give up many easy-scoring chances. The 49ers aren’t very good defensively, and they’re giving up more than 80 points per game on the road, so expect them to have a hard time slowing down the Mountaineers. Take Appalachian State to cover the spread.
Over/Under Pick for Charlotte vs. Appalachian State
- Over (4 Units)
The 49ers average 73.3 points per game. They play at the 347th-fastest pace in the nation, averaging 67.2 possessions per game, and they’re facing a team that is giving up 66.8 points per game. The Mountaineers average 74.4 points per game. They play at the 354th-fastest pace in the nation, averaging 66.5 possessions per game, and they’re facing a team that is giving up 84 points per game on the road. Expect these teams to score enough points to push the score over the total. The 49ers and Mountaineers played over the total in their last two meetings.
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