DePaul Blue Demons vs Butler Bulldogs Picks, Prediction, Odds, and Line Movement for Tuesday January 20 2026

By: Kyle Kargel Published 01/20/2026, 09:25 AM ET
DePaul vs Butler prediction
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DePaul heads to Indianapolis for a classic Big East road test at Hinkle Fieldhouse against Butler, a matchup where home-court edge and recent market movement are front and center. With the spread favoring the Bulldogs and the total sitting north of 150, this game stands out on Tuesday’s college basketball picks board for bettors weighing pace versus environment.

Quick Picks and Prediction

  • Spread Pick: Butler -7.5
  • Total Pick: Under 150.5
  • Projected Final Score: Butler 78, DePaul 69

Odds and Line Movement

Opening Odds

Team Spread Total
DePaul +7.5 (-105) Over 148.5 (-112)
Butler -7.5 (-105) Under 148.5 (-108)

Current Odds

Team Spread Total
DePaul +7.5 (-105) Over 150.5 (-110)
Butler -7.5 (-105) Under 150.5 (-110)

Line Movement - Spread

Time DePaul Butler
Opening +7.5 -7.5
Key Move +7.5 -7.5
Current +7.5 -7.5

Line Movement - Total

Time Over Under
Opening 148.5 148.5
Key Move 150.5 150.5
Current 150.5 150.5

Key Matchups and Handicap

This matchup hinges on whether DePaul’s recent offensive ceiling can travel into one of the league’s most demanding home environments. The Blue Demons come in capable of controlled, lower-possession basketball, which can keep underdogs live if shots fall and turnovers are limited.

Butler’s edge is built on home consistency and shot efficiency. Playing at Hinkle Fieldhouse has historically amplified defensive pressure and rewarded teams that value the ball. If Butler dictates tempo and forces DePaul into extended half-court possessions, the spread becomes more attainable.

  • Butler has been strong at home this season.
  • DePaul has shown the ability to keep games close with a slower tempo.
  • Recent Butler games have supported higher totals, while DePaul’s trend leans lower.

Key Injuries and Notes - DEP and BUT

  • Butler lists Jalen Jackson out for the season.
  • DePaul has multiple rotation players listed as out or questionable.
  • Backcourt depth could influence late-game execution.

ATS and Total Picks

  • Against the Spread: Butler -7.5
  • Total: Under 150.5

Final Score Prediction

Butler leverages home-court control and shot efficiency to separate in the second half.

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Final Score: Butler 78, DePaul 69

How to Bet

This game profiles as a home-favorite spot where environment and pace matter. Compare prices across the best sportsbooks and look for added value using available sportsbook promo codes.

Bettors seeking alternative options can explore social sportsbooks, while bonus hunters may want to check the bet365 bonus code or the fliff promo code before tipoff.

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