DePaul Blue Demons vs. UConn Huskies Picks, Prediction, Odds and Line Movement for Saturday, January 10, 2026
It’s a battle of Big East foes on the hardwood as the DePaul Blue Demons take on the #4 UConn Huskies Saturday afternoon in the Constitution State and we have you covered with our DePaul vs. UConn prediction. DePaul downed Georgetown 56-50 at home in their previous game Tuesday night, covering the line as a 2.5-point favorite. UConn dropped Providence 103-98 on the road in their previous contest Wednesday, failing to cover the line as a 9.5-point favorite. In the all-time series between the teams, the Huskies own a commanding 22-1 advantage and have won the last 21 meetings, including a 72-54 road win in the most recent matchup December 21, 2025. Read more about this DePaul vs. UConn prediction! Struggling with handicapping? Try our NCAAB Predictions!
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DePaul Seeking to Maintain Recent Momentum
DePaul won their second straight as they held off Georgetown at home in their previous contest Tuesday night. The Blue Demons improved to 10-6 overall and 2-3 in the Big East on the year. Against Georgetown, DePaul led by as many as seven in the first half only to trail by three at intermission. The Blue Demons clamped down defensively, outscoring the Hoyas 24-15 in the second half, to earn the victory. DePaul shot 35.3% from the field, including seven of 20 from three-point range, and overcame 15 turnovers in the win. Brandon Maclin led the Blue Demons with 13 points and 11 rebounds off the bench in the win.
The Blue Demons are average on the offensive end of the floor as they put up 73.7 points per game on the year, putting them 262nd in the nation in scoring offense. DePaul pulls down 34.4 rebounds per contest (269th) and dishes out 16 assists a night this season. The Blue Demons are above average on the defensive end, ranking 70th by allowing 68.4 points per contest. CJ Gunn leads the team and is one of three players averaging in double figures with 13.7 points and 3.4 rebounds per game. NJ Benson (10.7 points, 7.1 rebounds) and Layden Blocker (11.4 points, 3.8 assists) are the most reliable secondary scoring options. Brandon Maclin, Theo Pierre-Justin, Kaleb Banks, RJ Smith, Ilija Milijasevic, Jeremy Lorenz, Kruz McClure and Khaman Maker are other key players for the Blue Demons for coach Chris Holtmann. DePaul shoots 44.5% from the floor as a team this season. The Blue Demons knock down 7.3 triples a night (242nd) while connecting on 33.4% (211th) from beyond the arc. DePaul is below average when it comes to their free throw chances as they sink 69.5% of their opportunities on the year, leaving them 265th in the nation.
Key Injury Report for DePaul:
- Forward Jeremy Lorenz (undisclosed) is questionable.
- Guard Kruz McClure (undisclosed) is questionable.
Huskies Shooting for 12th Straight Win
UConn needed to rally but still managed to take down Providence in overtime on the road in their previous contest for their 11th straight win. The Huskies improved to 15-1 overall and stand 5-0 in the Big East on the year. Against Providence, UConn trailed by as many as 13 in the first half and by 10 at intermission. The Huskies still trailed by 11 with 3:12 remaining in regulation before outscoring the Friars 14-3 the rest of the way to force overtime. In overtime, UConn scored seven of the first 10 points and led the rest of the way en route to the win. UConn shot 49.3% from the field, including 18 of 32 from three-point range, and forced 17 turnovers in the win. Braylon Mullins led the Huskies with 24 points in the win.
The Huskies are above on the offensive end of the floor as they put up an average of 80.4 points per game, putting them 116th in the nation in scoring offense. Connecticut is grabbing 37.5 boards a night (135th) while they are dishing out 18.9 assists a night, putting them 16th in the nation. The Huskies are above average on the defensive end, ranking 11th by allowing 63.5 points a night. Alex Karaban is third on the team with 13.9 points, 5.3 rebounds and 2.2 assists per game this season. Solo Ball (15.3 points), Silas Demary Jr. (9.9 points, 4.4 rebounds, 6.3 assists) and Tarris Reed Jr. (14.5 points, 7.7 rebounds) are solid secondary scorers. Jayden Ross, Braylon Mullins (11.3 points), Malachi Smith, Jaylin Stewart, Eric Reibe, Dwayne Koroma and Alec Millender are critical pieces of the rotation for Dan Hurley and the Huskies. Connecticut is shooting 49.3% from the field as a team this season, which is 33rd in Division I. The Huskies average 8.3 three-pointers a game while shooting 36.4% from three-point range, which is 66th in Division I. Connecticut has knocked down 70.8% of their attempts at the charity stripe this season, which is 215th in the nation.
Key Injury Report for UConn:
- No Key Injuries
DePaul vs. UConn Pick
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Tony Karpinski | +2,494.00 |
| 2 |  Joe Duffy | +1,859.00 |
| 3 |  The Insiders Room | +1,788.00 |
| 4 |  Mark Ruelle | +1,428.00 |
| 5 |  Jackie Mack | +1,400.00 |
DePaul vs. UConn Spread Pick
- UConn -19.5 (4 units)
UConn has been rolling since their loss to Arizona before Thanksgiving, winning 11 straight contests. That includes triumphs over Illinois, Kansas, Florida and Texas, all of whom are in the top 51 of the KenPom rankings. As for DePaul, they have a winning record but they have beaten up on some weak fodder. The Blue Demons own five wins over teams ranked in the bottom 50 of the KenPom rankings while a sixth came over a Detroit Mercy squad ranked 280th on the year. The Blue Demons are 0-4 against teams ranked in the top 50 of the KenPom rankings and have dropped 21 straight meetings in the series. It’s safe to say that UConn is the toughest team the Blue Demons have faced and they don’t match up here. Take the Huskies in this contest.
DePaul vs. UConn Over/Under Pick
- Under 136.5 (4 units)
On the season, the Blue Demons have seen the under post a 11-5 mark in their 16 games. That includes an under in each of their three road contests of the season. DePaul is 49th in defensive efficiency, 35th in effective field goal percentage defense (46.4%) and 78th in forced turnover percentage (19.2%) on the year. The Blue Demons are 190th in adjusted tempo with 68.1 possessions per game. UConn has seen the under post an 11-5 mark in their 16 games in relation to the total this season. The Huskies are 5th in defensive efficiency, 3rd in effective field goal percentage defense (43%), 85th in forced turnover percentage (19%) and 10th in field goal percentage defense (38.1%) this season. UConn is 286th in tempo with 66 possessions a night. We saw just 126 points in the first meeting this season. Don’t expect much more offense here so take the under.
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