Drexel Dragons vs. Syracuse Orange Picks and Prediction for Saturday, November 15th, 2025

By: Adam Rauzino Published 11/15/2025, 12:11 AM ET
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The Drexel Dragons (1-2, 0-2 ATS, 2-0/U) take on the Syracuse Orange (2-0, 2-0 ATS, 0-2 O/U) in an inter-conference meeting on Saturday afternoon, and we have you covered with the prediction. The Dragons are 2-1 after three games, after a win against Colgate in their previous action. The Orange posted a home win against Delaware State on Saturday.

Can Syracuse continue their dominance by winning this one by more than 20 points? Check out the Drexel vs. Syracuse prediction. Do you need a boost in your handicapping? Try our NCAAB Picks!

Drexel Eyes Second Win of Season

The Drexel Dragons are seeking their second win of the season on Saturday. Drexel has dealt with a busy schedule in the opening few weeks. They have played three games, registering a 1-2 record. They opened the season against a non-DI opponent, Widener, and did as expected, and came away with an easy 93-59 win. Next, they had a tough one and were hit with a 76-65 road loss against St. Joseph’s of the A10. Drexel was hit with a disappointing 90-83 road defeat against Colgate on Tuesday in a clash that had the Dragons as four-point favourites. Drexel shot 45% but struggled defensively as Colgate sank 60% of their shots.. The Dragons have covered the spread in one of two games.

Josh Reed has already displayed progress compared to last season. The sophomore guard averaged just 1.2 PPG in limited playing time in his freshman season. Reed has already recorded an average of 9.7 PPG and 5.3 PPG in three games. Garfield Turner scored just two points in the defeat on Tuesday. The senior forward played off the bench last season and has averaged 7.3 PPG and 5 RPG on the season.

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Dillon Tingler is a new transfer. The sophomore guard spent last season with Eastern Michigan of the MAC. He has posted 6 PPG. Shane Blakeney was a key player on last year’s team. The junior guard amassed 7.5 PPG last year and has scored nine or more points in all three games this season, including 24 points on Tuesday. He has delivered 14.3 PPG. Kevon Vanderhorst has been steady, amassing an average of 10.7 PPG on a 55% mark.

Drexel is ranked 250th in DI in Ken Pomeroy’s ratings and was voted to finish in 10th place in the CAA preseason poll chosen by the media. Drexel is averaging 80.3 points after three games, ranking them 253rd. They are shooting 43% while keeping opponents to a 43.9% mark. The Dragons' defense has been their top strength early this season, conceding an average of 75 points, placing them 190th.

Syracuse Improves to 2-0 on Season

The Syracuse Orange are seeking a third straight win to begin the season. The Orange had enjoyed an easy schedule, but has a few games against ranked opponents later this month. Syracuse began the season with a dominating 85-47 home win against Binghamton. Next, they had an even easier opponent in an 83-43 home win against Delaware State on Tuesday to cover the big 16.5-point spread. They shot 50% in the win. The Orange have covered the spread in each of their two games.

Donnie Freeman is a key player. The sophomore forward averaged 13.4 PPG in his freshman season and could be one of the better players in the ACC. He has dominated in two games, sinking 20 PPG and 5.5 RPG. William Kyle III has spent three seasons in DI. He spent last season with UCLA. The senior forward has averaged 12 PPG and 9 RPG in two games.

Kıyan Anthony is a talented freshman who has made it look easy so far. The point guard scored 15 points in the opener and delivered 19 points against Delaware State. He has connected on 66% of his shots. Nathan George was the Orange's biggest transfer. The junior guard reported 12.3 PPG with Georgia Tech last season. George has scored 21 points and 11 assists in two games. Nate Kings has been kept in check so far, scoring just 11 points,

The Orange are marked 59th in the country in  Ken Pomeroy’s ratings. They were chosen to finish in 9th place in the ACC preseason poll selected by the media. This is not bad considering the ACC has 18 teams. Syracuse has averaged 84 points in its two games, ranking them 216th. They are shooting a sharp 55%. The defense has been among the best, although it’s only been two games. The Orange are keeping opponents to 26% shooting. The Orange have conceded an average of just 45 points, leading the entire country.

Drexel vs. Syracuse Pick

Spread Pick for Drexel vs. Syracuse

  • Drexel Dragons +16 (5 units)

The Drexel Dragons are going to be a competitive team this season. They have won two of three games after a win against Colgate. The Syracuse Orange have taken advantage of an easy schedule. Their two games were against Binghamton and Delaware State. These teams are ranked 330-360th in the country in Ken Pomeroy’s ratings. Drexel is a step up in competition.

Furthermore, the Dragons have the defense to stay in this game. They are conceding 109.8 points per 100 possessions according to Ken Pomeroy’s ratings, compared to 99.9 points per 100 by the Orange, making this spread more than favorable for Drexel. Despite the easy opposition, Syracuse has been abysmal when it comes to shooting threes, posting a 28.6% mark.

Over/Under Pick for Drexel vs. Syracuse

  • Over 146 (5 units)

I expect this one to have plenty of scoring.  Drexel has been sharp in the offensive end. They have averaged 80 points in their three games. They will take a decent amount of threes, averaging 29.5 three-point attempts per game.

In addition, Syracuse has connected on 55% of its field goals. Yes, it was against weak opposition, but this is a talented offensive squad that will give teams in the ACC some issues. Also, Syracuse ranks above average in adjusted tempo, which should help Drexel produce more points. The over is a convincing 5-0 in the Dragons' past five November games.

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