Duquesne Dukes vs. Villanova Wildcats Picks and Prediction for Saturday, November 15th, 2025
The Duquesne Dukes (3-0, 1-2 ATS, 3-0 O/U) meet the Villanova Wildcats (2-1, 3-0 ATS, 1-2 O/U) in an inter-conference bout on Saturday afternoon, and we have you covered with the prediction. The Dukes posted a win against Queens, NC, on Tuesday. The Wildcats netted a win against Sacred Heart in their recent action. There are no recent meetings between these squads.
Can the Dukes keep this one within reach on the road? Check out the Duquesne vs. Villanova prediction. Do you need a boost in your handicapping? Try our NCAAB Picks!
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Duquesne Remains Undefeated on Season
The Duquesne Dukes are seeking their third win of the season on Saturday. Duquesne is looking good early this season, but it was to be expected considering they were tabbed as the heavy favorite in each game. The Dukes opened the season with a home win against Niagara. They defeated Sacred Heart in their second game last weekend and posted an 87-81 overtime home win against Queens NC on Tuesday, but didn’t come close to covering the 12-point spread. They shot 50% in the victory, while keeping them to a 37% mark. The Dukes have covered the spread in one of three games on the season.
Tarence Guinyard is in his first season with Duquesne after averaging 16 PPG with UTM last year. The senior guard has been outstanding, sinking 19 or more points in two of three games. He is averaging 18 PPG. John Hugley IV spent last season with Xavier, where he came off the bench. The senior forward has been outstanding. He scored 25 points last Friday and is averaging 19.7 PPG on 62% shooting.
Jimmie Williams has been a threat, sinking double digits in two of three games. The junior guard has an average of 10 PPG. Cam Crawford was a key player last season and is poised for a big season. The senior guard has been shaky so far. He scored three points on Tuesday and has posted an average of 6.3 PPG on 30% shooting. David Dixon averaged nearly 6 PPG last year. The senior forward amassed five points on Tuesday and has reported 4.3 PPG.
The Dukes are ranked 109th in the country in Ken Pomeroy’s ratings and were voted to finish in 9th place in the A10 preseason poll chosen by coaches. Duquesne is averaging 87.3 points after three games, ranking them 190th. They are shooting 49.7%. The Dukes are keeping the opposition to 38.5% shooting. The Dukes have conceded an average of 75 points, placing them 158th.
Villanova Seeks Third Win of Season
The Villanova Wildcats are targeting their second win of the season. Villanova had a tough matchup to begin the season and was competitive. They were charged with a 71-66 defeat against BYU in a clash that had the Wildcats as big 9.5-point dogs. Next, the group answered with a blowout win against Queens NC. The Wildcats improved to 2-1 with an easy 94-60 home win against Sacred Heart on Tuesday, covering the 19-point spread. They shot 55% in the win. The Wildcats have covered the spread in each game.
| # | Handicapper | Profit |
|---|---|---|
| 1 |  David Hess | +1,568.00 |
| 2 |  Ben Burns | +982.00 |
| 3 |  Tony Karpinski | +572.00 |
| 4 |  Joe Duffy | +501.00 |
| 5 |  Ross Benjamin | +328.00 |
Bryce Lindsay was a big scorer for James Madison last season, and so far, he has dominated with his new team. The sophomore guard sank 22 points in the opener against BYU and is sporting an average of 24.7 PPG on a 51% efficiency. Duke Brennan is going to be a big contributor this season. The senior forward averaged 10 PPG with Grand Canyon last year. Brennan scored 10 points on Tuesday and is averaging 11.7 PPG.
Acaden Lewis is a freshman with talent and could be a top NBA pick. The guard scored 21 points last Saturday. He has amassed an average of 10 PPG and 5 APG. Matt Hodge is another freshman playing big minutes. The forward only managed six points in the win on Tuesday. He has averaged 25 minutes of playing time. Hodge has contributed 10.3 PPG. Tyler Perkins is expected to be a key player after a promising year. He averaged 6 PPG last year. The junior guard has netted 8 PPG. Chris Jeffrey is a freshman averaging 9.5 PPG.
Villanova is ranked 42nd in the country in Ken Pomeroy’s ratings. They are not expected to make noise in the Big East, considering they were chosen to rank 7th in the Big East preseason poll, chosen by media members. Villanova is posting an average of 85 points, ranking them 212th. They have connected on 47% of their shots while opponents have sunk 45% of their shots against them. The Wildcats have kept the opposition to an average of 68.3 points, placing them 106th.
Duquesne vs. Villanova Pick
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Earle Sports Bets | +2,298.00 |
| 2 | Ross Benjamin | +1,840.00 |
| 3 |  Rob Vincilleti | +1,757.00 |
| 4 | David Hess | +1,745.00 |
| 5 |  Dan Kaiser | +987.00 |
Spread Pick for Duquesne vs. Villanova
- Duquesne Dukes +10.5 (5 units)
The Duquesne Dukes are a competitive group this season. They have won all three games, winning by six or more points in each effort. The Villanova Wildcats are 2-1. It is more of a development season for the Wildcats, and they are not deemed a threat in the Big East this season.
Furthermore, the Dukes' defense is a strength and will keep them in this one. They are conceding only 3.7 fewer points per 100 possessions than the Wildcats. The Dukes are keeping opponents to under 39% shooting. Villanova has been shaky defensively. Opponents are shooting on 39.1% from beyond the arc against the Wildcats, ranking them 330th in the country.
Over/Under Pick for Duquesne vs. Villanova
- Over 147 (5 units)
I expect a shootout. Duquesne has been a big threat in the offensive end, sinking just under 50% of its field goals. I expect more success considering the Wildcats are pegged 259th in DI in field goal defense. They have squandered 70+ points in two of three games.
In addition, Villanova is also in a groove offensively after a shaky opener, connecting on 51% and 55% of their shots in its past two games. This is a potent offense that ranks 46th in the entire country in adjusted offensive efficiency. The over is a convincing 5-1 in the Dukes’ past six road games.
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