LSU Tigers vs. Vanderbilt Commodores Picks and Prediction for Saturday, January 10, 2026
LSU (12-3, 0-2 SEC) will be trying to pick up their first conference win of the season when they visit Memorial Gymnasium on Saturday afternoon to face Vanderbilt (15-0, 2-0 SEC) at 1 PM. ET. Read on to find out which team picks up the win in this Tigers vs. Commodores prediction. If you are struggling to pick winners, you've come to the right place. We have the best NCAAB Predictions available.
The Tigers are coming off a 78-68 loss to South Carolina as 7.5-point favorites. The Commodores are coming off a 96-90 win over Alabama as 3.5-point favorites.
LSU is 6-4 in its last 10 games against Vanderbilt.
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LSU Trying To Snap Two-Game Losing Streak
The Tigers followed up their four-game winning streak with two straight losses. They will try to snap their losing streak and pick up their first conference win of the season when they play on Saturday.
LSU averages 86.5 points per game. They’ve made 50.2 percent of their field goals and 33.1 percent of their three-pointers.
Dedan Thomas Jr. leads the Tigers with 16.2 points and 7.1 assists per game. Mike Nwoko averages 15.7 points and six rebounds per game, while Max Mackinnon averages 13.6 points and 2.6 rebounds per game.
LSU is giving up 71.7 points per game. Opponents have made 41 percent of their field goals and 35 percent of their three-pointers against them.
Injuries: Dedan Thomas Jr. (Undisclosed) is questionable for this game. Jalen Reed (Leg) has been ruled out.
Vanderbilt Trying To Stay Perfect
The Commodores are off to one of the best starts in school history after a 15-0 start to the year. They are one win away from tying the best start in school history and will try to accomplish the feat with a win on Saturday.
Vanderbilt averages 93.6 points per game. They’ve made 50.8 percent of their field goals and 38 percent of their three-pointers.
Duke Miles leads the Commodores with 17.2 points and 4.4 assists per game. Tyler Tanner averages 17.1 points and 5.6 assists per game, while Tyler Nickel averages 14.7 points and 3.1 rebounds per game.
Vanderbilt is giving up 72 points per game. Opponents have made 39 percent of their field goals and 27 percent of their three-pointers against them.
Injuries: Frankie Collins (Lower Body) has been ruled out of this game.
LSU vs. Vanderbilt Picks
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Tony Karpinski | +2,494.00 |
| 2 |  Joe Duffy | +1,859.00 |
| 3 |  The Insiders Room | +1,788.00 |
| 4 |  Mark Ruelle | +1,428.00 |
| 5 |  Jackie Mack | +1,400.00 |
Point Spread Pick for LSU vs. Vanderbilt
- Vanderbilt Commodores to cover. (4 Units)
The Commodores have the edge in this game because they have one of the best offenses in the country, and they play better at home, where they score more than 96 points per game while making over 51 percent of their shots. They do a good job of finding the open man, and they rebound the ball well, grabbing more than 10 offensive rebounds per game at home, which will give them more scoring chances. They also do a good job of protecting the ball, turning it over less than 10 times per game, so don’t expect them to give up many easy-scoring chances. The Tigers aren’t very good defensively, and they gave up at least 75 points in their last two games, so expect them to have a hard time slowing down the Commodores. Take Vanderbilt to cover the spread.
Over/Under Pick for LSU vs. Vanderbilt
- Over (4 Units)
The Tigers average 86.5 points per game. They play at the 160th-fastest pace in the nation, averaging 72 possessions per game, and they’re facing a team that is giving up 72 points per game. The Commodores average 93.6 points per game. They play at the 25th-fastest pace in the nation, averaging 76.4 possessions per game, and they’re facing a team that is giving up 71.7 points per game. Expect these teams to score enough points to push the score over the total. The Commodores and Tigers played over the total in four of their last six meetings.
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