Memphis Tigers vs. Louisville Cardinals Picks and Prediction for Saturday, December 13, 2025
Use Code WWWC It’s an early season clash on the hardwood and it brings a non-conference tilt between foes from the AAC and the ACC on the hardwood in the Bluegrass State as the Memphis Tigers take on the #11 Louisville Cardinals Saturday afternoon and we have you covered with our Memphis vs. Louisville prediction. Memphis comes in off a 78-71 home win over Baylor in their previous game last Saturday, winning outright as a 3.5-point underdog. Louisville downed #22 Indiana 87-78 on a neutral floor in Indianapolis Saturday night, covering the line as a four-point favorite, in their previous game. In the all-time series between the teams, the Cardinals own a 54-36 advantage, including an 81-72 win in the most recent matchup, which came in the Gotham Classic in New York City on December 16, 2017. Read more about this Memphis vs. Louisville prediction! Struggling with handicapping? Try our NCAAB Predictions!
Memphis Seeking Fourth Straight Win
Memphis earned a third straight victory after four straight losses as they took down Baylor at home in their previous game. The Tigers improved to 4-4 on the year and look to earn an upset win on the road to maintain their momentum. Against Baylor, Memphis led by as many as eight in the first half before settling for a three-point edge at intermission. The Tigers faced their biggest deficit at 53-45 with 12:42 remaining before rallying to take the lead for good at 64-63 with 5:03 remaining on a pair of free throws by Sincere Parker en route to the win. Memphis shot 41.2% from the field, including three of 16 from beyond the arc, and held Baylor to 34.4% shooting. Zach Davis paced the Tigers with 23 points and 13 rebounds in the win.
On the season, Memphis is averaging 76 points per game this season, putting them 212th in the nation in that department. The Tigers are grabbing an average of 37.5 rebounds per contest while dishing out an average of 14.8 assists a night. Memphis is average in scoring defense as they give up an average of 74.1 points per contest, putting them 210th in the nation in scoring defense. Sincere Parker is third on Memphis in scoring as he puts up nine points, 2.8 rebounds and one steal per game this season. Curtis Givens III (7.4 points, 1.4 steals) and Dug McDaniel (13.9 points, 6.4 assists, 1.9 steals) are solid scoring options on the year. Ashton Hardaway, Quante Berry, Julius Thedford, Simon Majok, Aaron Bradshaw, Zach Davis and Thierno Sylla have to step up and contribute offensively for Memphis. The Tigers are sputtering when it comes to shooting the ball as they are knocking down 43.2% of their shots from the floor. Memphis has knocked down an average of 7.1 three-pointers a game while shooting 32.4% from beyond the arc, which is 231st in the nation. The Tigers are below average at the charity stripe, connecting on 70.2% of their attempts this season.
Key Injury Report for Memphis:
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- Guard Julius Thedford (knee) is doubtful.
- Guard Curtis Givens III (thigh) is doubtful.
Cardinals Shooting to Roll at Home
Louisville bounced back from a loss to #25 Arkansas as they took down #22 Indiana in Indianapolis in their previous contest. The Cardinals improved to 8-1 on the season and look to add another home win to their resume. Against Indiana, Louisville never trailed as they rolled to a 16-0 lead with 14:09 to play in the first half and maintained control the rest of the way. The Cardinals were up 14 at the half and didn’t let the Hoosiers closer than seven en route to the win. Louisville shot 46.3% from the field, including 13 of 31 from beyond the arc, and drained 24 of 28 free throw attempts in the contest. Ryan Conwell led the Cardinals with 21 points in the win.
The Cardinals enter the game 10th in scoring offense with 93.8 points per contest this season. Louisville is 11th in the nation in rebounding with 43.6 per contest while the team is 16th in Division I by dishing out 19.2 assists per contest. The Cardinals are above average defensively, ranking 68th in scoring defense as they allow an average of 67.6 points per game this year. Mikel Brown Jr. is second on the team with 16.7 points plus 5.3 assists per game this season. Ryan Conwell (19.7 points, 4.8 rebounds), Khani Rooths (12 points, 5.7 rebounds) and Isaac McKneely (12.4 points, 3.6 rebounds) are good secondary options offensively. J’Vonne Hadley (9.8 points, 5.8 rebounds), Sananda Fru (10.6 points, 6.2 rebounds), Adrian Woolley, Kobe Rodgers, Vangelis Zougres, Kasean Pryor and Aly Khalifa are other contributors for coach Pat Kelsey. Louisville shoots 47.2% from the floor as a team this season. The Cardinals are splashing 12.7 triples a night (3rd) while shooting 36% from beyond the arc. Louisville has been above average at the charity stripe in their attempts by cashing in 77.1% of their attempts this season.
Key Injury Report for Louisville:
- No Key Injuries
Memphis vs. Louisville Pick
Memphis vs. Louisville Spread Pick
- Louisville -15.5 (4 units)
Memphis has won three straight games but all that has done is push the Tigers to the .500 mark on the season. They did pick up a nice win over Baylor but their success is tied to being the home team. Memphis is 4-1 at home on the year but they dropped both their games on a neutral floor this season in addition to a six-point loss at Ole Miss in their lone true road game. Meanwhile, Louisville is a perfect 6-0 at home with five of those wins coming by double figures. The Cardinals already own wins over Kentucky and Indiana, a pair of bluebloods. With Memphis struggling to shoot the ball and unable to win outside of Bluff City, take the Cardinals here.
Memphis vs. Louisville Over/Under Pick
- Over 160.5 (4 units)
Memphis has stayed under the total in five of their eight games this season. The Tigers are 103rd in offensive efficiency despite ranking 239th in effective field goal percentage (49%), 278th in field goal percentage (43.2%) and 302nd in two-point shooting (49.2%) this season. Memphis is 123rd in adjusted tempo with 69.8 possessions per game on the year. Louisville has seen the over post a 5-4 mark on the year. The Cardinals are fourth in offensive efficiency, 31st in effective field goal percentage (57%), 40th in turnover percentage (14.4%), 67th in offensive rebounding percentage (35.5%) and 29th in two-point shooting (60.6%) on the year. Louisville is 37th in tempo with 71.7 possessions a night. With both teams willing to run and the Tigers’ issues on the defensive end of the floor, look for this game to go over the number.
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