Notre Dame Fighting Irish vs. Ohio State Buckeyes Picks and Prediction for Sunday, November 16, 2025
It’s an early season clash on the hardwood and it brings a non-conference tilt between foes from the ACC and the Big Ten on the hardwood in the Buckeye State as the Notre Dame Fighting Irish take on the Ohio State Buckeyes Sunday afternoon and we have you covered with our Notre Dame vs. Ohio State prediction. Notre Dame rolled past Eastern Illinois 78-58 at home in their previous game Tuesday night, failing to cover the line as a 24.5-point favorite. Virginia trounced Appalachian State 75-53 at home Tuesday night, failing to cover the line as a 23-point favorite, in their previous game. In the all-time series between the teams, the Buckeyes own a 9-4 advantage and have won the last three meetings, including a 90-85 road win in the most recent matchup December 8, 2020. Read more about this Notre Dame vs. Ohio State prediction! Struggling with handicapping? Try our NCAAB Predictions!
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Fighting Irish Seeking 4-0 Start to Season
Notre Dame took care of business against Eastern Illinois in their previous contest to continue their strong start to the year. The Fighting Irish improved to 3-0 on the year and look to continue their early season success as they make their way on the road for the first time this season. Against Eastern Illinois, Notre Dame led 8-2 out of the gate, trailed 28-26 with 2:40 to play in the first half and took a 31-28 lead at intermission. The Fighting Irish used a 10-2 run early in the second half after the Panthers cut the margin to 38-36 and pulled away from there. Notre Dame shot 48.3% from the floor, including nine of 28 from three-point range, and won the rebounding battle 40-24 in the game. Markus Burton led the Fighting Irish with 21 points in the win.
The Fighting Irish stand 73rd in the nation in scoring offense as they average 89.7 points per game. Notre Dame is pulling down an average of 43 rebounds per contest (65th) while the team is dishing out 15.7 assists a night. The Fighting Irish are above average on the defensive end of the floor as they allow 65 points per game this year, leaving them 76th in scoring defense. Markus Burton leads the team with 19.3 points a night this season. Jalen Haralson (10.5 points, four rebounds) and Braeden Shrewsberry (13 points) are solid secondary scoring options. Cole Certa, Ryder Frost, Sir Mohammed, Garrett Sundra, Carson Towt, Kebba Njie, Logan Imes and Brady Koehler are other players averaging double-digit minutes on the year for coach Micah Shrewsberry and the team. Notre Dame shoots 50% from the field as a team on the year. The Fighting Irish connect on 12.3 three-pointers a night while shooting 42.5% from beyond the arc, which is 25th in the nation. Notre Dame is average at the charity stripe, cashing in 71.6% of their chances this season, putting them 167th in the nation.
Ohio State Looking to Remain Unbeaten
Ohio State dropped Appalachian State at home to maintain their perfect record on the season. The Buckeyes ran their mark to 3-0 on the year and seek to down the Fighting Irish for the fourth straight time. Against Appalachian State, Ohio State started slowly as they were down 22-10 with 8:13 to play in the opening half before regrouping. The Buckeyes closed the half on a 20-3 run to take a 30-25 advantage at intermission and blew the game open with a 27-7 run to start the second half, giving them a 57-32 edge with 9:24 to play, allowing them to cruise the rest of the way. Ohio State shot 40.7% from the floor, including seven of 27 from three-point range, and won the rebounding battle 42-31 in the game. Brandon Noel led the Buckeyes with 17 points and 11 rebounds in the win.
| # | Handicapper | Profit |
|---|---|---|
| 1 |  David Hess | +1,568.00 |
| 2 |  Ben Burns | +982.00 |
| 3 |  Tony Karpinski | +572.00 |
| 4 |  Joe Duffy | +501.00 |
| 5 |  Ross Benjamin | +328.00 |
On the season, Ohio State stands 32nd in the nation in scoring offense as they put up an average of 95.7 points per game. The Buckeyes are 179th in the country in rebounding with an average of 38.7 boards per game and 64th as they hand out an average of 18.7 assists per game on the year. Ohio State is 213th in the nation in scoring defense, as they allow 74.3 points per contest. Bruce Thornton is one of four players on the Buckeyes with 25.7 points plus 4.3 rebounds and four assists per contest this season. John Mobley Jr. (17 points, 2.7 rebounds, five assists) and Christoph Tilly (16.7 points, 6.7 boards) are solid secondary scoring options. Devin Royal (14 points, 5.5 rebounds), Brandon Noel, Amare Bynum, Gabe Cupps, Taison Chatman, Ivan Njegovan, Matthew Grujucic and Colin White are good contributors in the rotation. Ohio State shoots 56.6% from the field as a team on the year, which is 9th in Division I. The Buckeyes knock down an average of 10.3 three-pointers a game while sinking 40.3% of their attempts from beyond the arc, which is 45th in the country. Ohio State is above average at the free-throw line, sinking 77.6% of their attempts, which is 50th in the nation.
Royal (hip) missed the Appalachian State game and is questionable here.
Notre Dame vs. Ohio State Pick
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Earle Sports Bets | +2,298.00 |
| 2 | Ross Benjamin | +1,840.00 |
| 3 |  Rob Vincilleti | +1,757.00 |
| 4 | David Hess | +1,745.00 |
| 5 |  Dan Kaiser | +987.00 |
Notre Dame vs. Ohio State Spread Pick
- Ohio State (4 units)
Both teams have started the year 3-0 and neither side has had a game decided by less than 16 points this season. The Fighting Irish has shot the ball well in the early going but we’ll have to see if their offense travels well for this contest. Ohio State has been sharp offensively though their defense has been rather suspect as they are slightly below average in that department. The Buckeyes hope to have Royal back on the floor for this contest after he missed the Appalachian State contest. Look for Ohio State to shut down the perimeter shooting of the Fighting Irish and that helps carry them to a victory here.
Notre Dame vs. Ohio State Over/Under Pick
- Over (4 units)
Notre Dame has seen the over post a 2-1 mark in their first three games of the season. The Fighting Irish is 58th in offensive efficiency, 62nd in field goal percentage, 23rd in effective field goal percentage (60.1%), 15th in offensive rebounding percentage (44.1%), 16th in threes per game and 25th in three-point percentage. Notre Dame is 320th in tempo according to KenPom with 68.7 possessions a night. Ohio State has gone over the mark in two of their three games. The Buckeyes are 9th in field goal percentage, first in two-point shooting (72%), 45th in three-point shooting, fourth in effective field goal percentage (66.4%), sixth in free throw rate (.616 FT attempts per FG attempt) and ninth in free throws made per game (25.3) this season. Ohio State is 164th in tempo with 71.4 possessions per contest. Look for this game to wind up over the number as both teams are good offensively.
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