Ohio State vs. Michigan State, Picks and Prediction, Sunday, February 22, 2026

By: Bosun Akinpelu Published 02/22/2026, 04:35 AM ET
Buckeyes vs. Spartans prediction
Use Code WWWC

Ohio State (17-9, 5-6 Big Ten) will be going for their second consecutive win when they visit Breslin Center on Sunday afternoon to face #15 Michigan State (21-5, 11-4 Big Ten) at 1 PM. ET. Read on to find out which team picks up the win in this Buckeyes vs. Spartans prediction. If you are struggling to pick winners, you've come to the right place. We have the best NCAAB Predictions available. 

The Buckeyes are coming off an 86-69 Win over Wisconsin as 1.5-point favorites. The Spartans are coming off an 82-59 win over UCLA as 8.5-point favorites.

Michigan State is 6-4 in its last 10 games against Ohio State.

Ohio State Going For Third Win In Four Games

The Buckeyes bounced back from their loss to Virginia with a win over Wisconsin in their last game, giving them two wins in their last three games. They will try to keep the momentum going and get to .500 in conference play with a win on Sunday.

Get Free $30 Credit for Premium Picks + Exclusive Discounts

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Winners and Whiners may use third-party services to process my data.

Ohio State averages 81.2 points per game. They’ve made 49 percent of their field goals and 35 percent of their three-pointers.

Bruce Thornton leads the Buckeyes with 19.9 points and 5.4 rebounds per game. John Mobley Jr. averages 15.1 points and 2.8 assists per game, while Devin Royal averages 14 points and 5.6 rebounds per game.

Ohio State is giving up 73.4 points per game. Opponents have made 43 percent of their field goals and 31 percent of their three-pointers against them.

Injuries: John Mobley Jr. (Hand) has been ruled out of this game.

Michigan State Going For Second Consecutive Win

The Spartans bounced back from their loss to Wisconsin with a blowout win over the Bruins in their last game, keeping them within 3.5 games of the conference lead. They will try to keep the momentum going and pick up their second straight win when they play on Sunday.

Michigan State averages 78.9 points per game. They’ve made 47 percent of their field goals and 35 percent of their three-pointers.

Jeremy Fears Jr. leads Michigan State with 15.1 points and 9.3 assists per game. Jaxon Kohler averages 12.4 points and 9.3 rebounds per game, while Coen Carr averages 11.9 points and 5.2 rebounds per game.

Michigan State is giving up 66.4 points per game. Opponents have made 40 percent of their field goals and 31 percent of their three-pointers against them.

Injuries: Divine Ugochukwu (Foot) is questionable for this game.

Ohio State vs. Michigan State Picks

Point Spread Pick for Ohio State vs. Michigan State

  • Michigan State Spartans to cover. (4 Units)

The Spartans have won 13 of their 15 home games, while the Buckeyes split their eight road games. Michigan State has the edge here because they’re shooting the ball well, scoring over 78 points per game, while making 47 percent of their shots. They’ve also done a better job at the charity stripe, making over 90 percent of their free throws in their last three games. Their rebounding is very good, and they grab more than 11 offensive rebounds per game, which will give them more scoring opportunities. They also cut down their turnovers in recent games, and won’t give up many easy-scoring chances. The Buckeyes aren’t very good defensively, and they’re giving up more than 74 points per game on the road, so expect them to have a hard time slowing down the Spartans. Go with Michigan State to cover the spread.

Over/Under Pick for Ohio State vs. Michigan State

  • Under (4 Units)

The Buckeyes average 81.2 points per game. They play at the fastest pace in the nation, averaging possessions per game, and they’re facing a team that is giving up 65.6 points per game at home. The Spartans average 78.9 points per game. They play at the fastest pace in the nation, averaging possessions per game, and they’re facing a team that is giving up 74.7 points per game on the road. Don’t expect these teams to score enough points to push the score over the total. The Buckeyes and Spartans played under the total in four of their last five meetings.

Betting on College Basketball?

BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $200 in Bonuses Instantly!

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Odds Requirements -500
Cashable No

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.