Oklahoma State Cowboys vs. Colorado Buffaloes Picks and Prediction for Saturday, February 26 2026

By: Ben Hayes Published 02/21/2026, 04:30 AM ET
Oklahoma State vs. Colorado pick, odds and prediction
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The Big 12 is in action on Saturday afternoon, led by this Oklahoma State vs. Colorado prediction. These teams will meet for the first time this season at 3:30 PM ET from Boulder. Neither team is looking at an NCAA Tournament bid as both squads are 4-9 in the Big 12, sitting at tied for 12th. The Cowboys (16-10) have lost four straight games, including an 81-69 defeat at home against Kansas on Wednesday. The Buffs have lost two straight, including a 90-86 defeat at BYU last Saturday. Check out more free College Basketball Predictions and NBA picks at Winners and Whiners.

Too much Peterson for Cowboys

Kansas freshman wing Darryn Peterson scored 23 points in just 19 minutes on 7-of-12 shooting against Oklahoma State on Wednesday at Gallagher-Iba Arena. Parsa Fallah led the Cowboys with 21 points, while Anthony Roy chipped in with 16, but shot just 4 of 14 from the field. The Cowboys fell to the No. 8 Jayhawks by 12 at home as a 6.5-point dog. OK State beat BYU on Feb. 4 as a 7.5-point home underdog but since then, has lost four straight games.

Oklahoma State (77th NET Rankings) is one below Colorado in the NET Rankings, which means they will basically have to win out. BYU was their only Quad 1 victory as they are 1-7. Oklahoma State is ranked 65th overall by KenPom, 61st in Adjusted Offensive Efficiency and 101st in Adjusted Defense. In terms of total rebounding percentage, they rank 162nd. Fallah leads Oklahoma State with 14.5 points and 6.1 rebounds, while Vyctorious Miller adds 12.0 points and shoots 39% from three-point range.

Tough loss for Buffs on the road

Colorado gave BYU all they could handle last Saturday, falling 90-86 in overtime as a 15.5-point dog. BYU lost its second-leading scorer, Richie Saunders (ACL), in the first minute. The Cougars survived because Robert Wright III had a career game with 39 points, but Colorado did a nice job on superstar freshman forward A.J. Dybantsa, who had 20 points but shot just 6 of 20 from the field. Isaiah Johnson led CU with 27 points on 10-of-23 shooting, while Barrington Hargress chipped in with 20 points on 7-of-11 shooting. Johnson and Hargress both played over 40 minutes.

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Depth has been a problem for the Buffs, who are led by Johnson (16.5 ppg, 49% FG, 38.1% 3pt) and Hargress (14.1 ppg, 4.3 apg, 50% 3pt). Colorado has just two wins in their last 11 games, after winning their first two conference games over Arizona State and Utah to open conference play in early January. According to KenPom, Colorado ranks 74th overall, 56th in Adjusted Offensive Efficiency and 135th in Adjusted Defense. In total rebound percentage, the Buffaloes rank 173rd.

Spread Picks and Odds for Oklahoma State vs. Colorado

Oklahoma State vs. Colorado Pick and Prediction

  • Colorado -3.5 (4 units)

Colorado is not an easy place to play. The Buffs are very average overall, but they are 11-4 at home, while the Cowboys are a pitiful 1-5 on the road. At one point, Oklahoma State was 12-1 and then reality struck. This is a team that shoots pretty well overall, but on the road, they are shooting about 41% (46% overall) from the field and allowing teams to shoot 45.6% from the field on the road. They also rank 162nd in total rebounding percentage and that's where Colorado has the major edge. Take the Buffs to win and cover at home.

Total Picks for Oklahoma State vs. Colorado

  • Under 162.5 (4 units)

Colorado has gone under in four of their last five games. Oklahoma State has gone under in three of their last four games and seven of their last nine. Aside from their shooting woes on the road, Oklahoma State is averaging just 70 points per game away from home. Both teams play pretty fast, but the Cowboys don't rebound well enough to push it up the floor on a consistent basis.

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