Penn State Nittany Lions at La Salle Explorers Odds, Preview, Picks and Prediction for Saturday, November 15, 2025

By: Liam Keating Published 11/14/2025, 11:53 PM ET
Penn State vs La Salle prediction
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Itโ€™s a matchup between two Pennsylvania teams on Saturday, Nov. 15. Read our Penn State vs La Salle prediction along with our NCAAB picks for the night. This game will be played at a neutral site in Philadelphia, with the game played at the Xfinity Mobile Arena, home of the 76ers. Penn State is 3-0 with all of its wins over mid-major competition. La Salle is 2-1 as they are coming off a loss to Big 5 opponent Temple. These two teams will meet with tip-off set for 1 P.M. EST.

Penn State starts season undefeated

Penn State is 3-0 overall this season. The Nittany Lions opened the year with an 8-point win over Fairfield at home. They went on the road to New Haven for the Chargers' first-ever Division I home game. The Nittany Lions defeated Fairfield by 44 points for the easy win.

In their last game, Penn State defeated Navy at home 80-71 on Tuesday, Nov. 11. Penn State never gave up the lead since the 15-minute mark in the first half. But, Navy did go on a 7-0 run late in the second half to cut the game to one possession. Penn State responded and was able to hold on for the win. Penn State shot 49% from the field and 31.6% from behind the arc. The Nittany Lions forced 16 turnovers, which led to 17 points. Freddie Dilione V led the team with 19 points from the bench.

Kayden Mingo leads the team in most offensive categories as he has a team-high with 15.7 points, 6 rebounds and 4 assists per game.

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Penn State is the 87th-ranked team according to KenPom. They are the 92nd-ranked team in offensive rating, while they are the 86th-ranked team in defensive rating.

Penn State is averaging 81 points per game, which ranks 247th. They are the 59th-ranked shooting team, making 50.3% from the field. The Nittany Lions are hitting 35.5% from behind the 3-point line, which places them 135th.

On defense, Penn State is allowing 61 points per game, placing them 31st. They are the 163rd defensive team, allowing 41.4% from the field. The Nittany Lions are giving up 23.2% from behind the 3-point line, which ranks 26th.

Penn State is 1-2 against the spread this season. The Nittany Lions have been double-digit favorites in every game this season. They did not cover against Navy and Fairfield, but they were able to cover on the road against New Haven. The under is 3-0 when Penn State has played this year.

La Salle coming off poor game against Temple

La Salle is 2-1 overall this season. The Explorers opened the season with a 28-point win over Coppin State at home. A few days later, La Salle defeated Monmouth 73-60 to start the season 2-0. The undefeated start to the season halted in the teamโ€™s latest game.

In their last game, La Salle lost 90-63 to Temple on the road on Tuesday, Nov. 11. The Explorers led 9-7 in the first few minutes of the game before the Owls went on a 10-0 run, which separated the two teams, leading to a big win for Temple. La Salle shot 37% from the field and 30.8% from behind the 3-point line. Temple fired 50% from the field and the 3-point line in the win. The Explorers were dominated on the glass as Temple out-rebounded them 44-29.

Jaeden Marshall leads the team in scoring with 16.7 points per game. Josiah Harris is grabbing a team-high 6.7 rebounds, while Ashton Walker is passing for 5.3 assists per game. Jerome Brewer is the only other player to average double-digit points, too.

La Salle is the 201st-ranked team according to KenPom. They are ranked 206th in offense rating and 207th in defensive rating.

La Salle is averaging 74.3 points per game, which ranks 300th. They are hitting 40.8% from the field, which ranks 302nd. They are the 84th-ranked 3-point shooting team which ranks 84th.

On defense, La Salle is allowing 70 points per game, which ranks 122nd. They are allowing 42.9% from the field, placing them 203rd. The Explorers are allowing 29.6% from behind the arc which places La Salleโ€™s defense 127th.

La Salle is 2-1 against the spread this season. The Explorers are 0-1 against the spread when they have been underdogs. The over is 2-1 when La Salle has played this season.

Penn State Nittany Lions vs La Salle Explorers Picks

Penn State vs La Salle Spread Pick

  • Take Penn State to cover (5 units)

Penn State will continue its run of defeating mid-major programs to start the season. The Nittany Lions have been efficient to start the season, which has been key. They are hitting over 50% from the field and they are going up against a La Salle defense that ranks 203rd in defensive field goal percentage. The amount of different scores for Penn State will be key in this one, too. The Explorers simply do not have enough playmakers to keep this game close as only two players are averaging in double-digits. La Salleโ€™s big loss to Temple earlier in the week was a big indicator that they wonโ€™t be able to compete with a Power-4 conference school.

Take Penn State to cover.ย 

Penn State vs La Salle Over/Under Pick

  • Take the under (5 units)

A slow, methodical pace to this game will be key for both teams. Penn State ranks 224th in adjusted tempo, while La Salle is placed 324th in adjusted tempo. Defense has been key for both teams in the first few games, too. Penn State ranks 86th in defense according to KenPom, while La Salle is allowing 70 points per game. With two offenses that bleed the clock along with strong defense, this will be a low-scoring game.

Take the under on Saturday.ย 

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