South Carolina vs. Northwestern Odds, Picks, and Prediction, Sunday, November 23, 2025
On Sunday, the South Carolina Gamecocks will play the Northwestern Wildcats in the Greenbrier Tip-Off, and we have you ready to go with our South Carolina vs. Northwestern prediction, odds, and preview. Tip-off from Colonial Hall in White Sulphur Springs, WV, is at 5:00 p.m. ET.
If you want the South Carolina vs. Northwestern prediction, read on to get our top NCAAB predictions and increase your bankroll!
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Gamecocks are a deep team
South Carolina (4-1 SU, 2-3 ATS, and 4-1 O/U) lost 79-72 to Butler (didn't cover four-point spread) in Friday's first round matcup of the Greenbrier Tip-Off.
USC trailed by seven at the half and couldn't complete the comeback, as the Gamecocks struggled from three-point range (7-for-26). Butler knocked down 42 percent of its threes and won the rebounding battle 48-29 with 15 offensive rebounds. The Bulldogs led by as many as 15 and never trailed.
South Carolina is led by senior guard Meechie Johnson, who scores 16.4 points per game on 40.0 percent shooting. He also averages 3.6 assists. A few other Gamecocks to watch in Sunday's game against Northwestern are freshman guard Eli Ellis (13.4 PPG and 3.4 APG), senior guard Mike Sharavjamts (11.8 PPG and 6.0 RPG), and senior guard Kobe Knox (7.6 PPG and 3.6 APG).
South Carolina scores 82.8 points per game (191st) on 45.6 percent shooting (189th), including 34.4 percent from beyond the arc (150th). Defensively, the Gamecocks give up 69.8 points per game (84th) on 41.8 percent shooting (138th), including 27.3 percent from three (48th). USC is ranked 90th in the country, with rankings of 88th in offensive efficiency and 96th in defensive efficiency, according to KenPom.
South Carolina Gamecocks Basketball Injury Report:
- No significant injuries.
Northwestern gets it done on both ends of the court
Northwestern (4-1 SU, 3-2 ATS, and 3-2 O/U) lost 83-78 to Virginia on Friday in the Greenbrier Tip-Off, covering as 5.5-point underdogs.
The Wildcats outshot the Cavaliers from the field and three-point range, but still couldn't pull off the win. UVA dominated on the glass, outrebounding NU 49-25 with 21 offensive rebounds, and knocked down 30 of its 36 free throws. Still, it was a solid effort by Northwestern, which led by as many as seven points and never trailed by more than eight.
Northwestern is paced offensively by Nick Martinelli. The senior forward averages 18.2 points and 5.8 rebounds per game with a 54.4 percent shooting percentage. A few other Wildcats to watch in Sunday's game against South Carolina are junior forward Arrinten Page (16.8 PPG and 7.8 RPG), junior guard Jayden Reid (14.6 PPG and 5.6 APG), and freshman forward Tre Singleton (7.8 PPG and 4.4 RPG).
Northwestern averages 83.0 points per game (190th) on 51.0 percent shooting (35th), including 40.7 percent from beyond the arc (27th). Defensively, the Cats give up 64.8 points per game (41st) on 36.5 percent shooting (25th), including 27.8 percent from three (61st). NU is ranked 46th in the country, with rankings of 54th in offensive efficiency and 48th in defensive efficiency, according to KenPom.
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Earle Sports Bets | +2,298.00 |
| 2 |  Ross Benjamin | +1,840.00 |
| 3 |  Rob Vincilleti | +1,757.00 |
| 4 |  David Hess | +1,745.00 |
| 5 |  Dan Kaiser | +987.00 |
Northwestern Wildcats Basketball Injury Report:
- No significant injuries.
South Carolina vs. Northwestern Pick and Preview
Spread Pick for South Carolina vs. Northwestern
- Wildcats cover spread (4 Units)
These programs play a similar style, but the Wildcats perform it at a higher level. They shoot over 40 percent from three, force more turnovers (16.1% opponent TO%), and take better care of the basketball (14th nationally in TOs per game). The Gamecocks trailed from start to finish in their opening round matchup of this tournament, while Northwestern battled from end to end against a solid Virginia squad. The Wildcats shoot a much higher field goal percentage than their opponent, and will score enough both inside the arc and beyond it to cover the spread on Sunday in West Virginia.
Over/Under Pick for South Carolina vs. Northwestern
- Under (5 Units)
The Wildcats and Gamecocks play a similarly slow tempo, ranking 280th and 283rd in schedule-adjusted pace, per KenPom. The Wildcats also play sound defense, ranking in the top 25 in opponent field goal percentage and top 75 in opponent three-point percentage. The latter will be especially impactful against a South Carolina squad that attempts a high volume of three-balls (49.5% 3PT rate), ranking 31st nationally. The Wildcats will also poke away a fair share of loose balls on defense, turning the Gamecocks over at least 15 times. These teams will play competitively in the first half before Northwestern pulls away to win, but neither team will dominate on the scoreboard. Bet on the under!
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