UConn Huskies vs Villanova Wildcats Picks and Prediction for Saturday, February 21, 2026

By: Liam Keating Published 02/21/2026, 03:25 AM ET
Georgetown vs Villanova prediction
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Itโ€™s an important matchup at the top of the Big East Conference on Saturday, Feb. 21. Read our UConn Huskies vs Villanova Wildcats prediction along with our NCAAB picks for the night.. UConn is ranked No. 5 in the nation with their 24-3 record. The Huskies are coming off a disappointing home loss to Creighton earlier this week. Villanova is riding a six-game win streak as they hold a 21-5 record. The Wildcats last loss was an OT defeat to UConn. These two teams will meet with tip-off set for 5:30 P.M. EST.

UConn coming off upset loss to Creighton

UConn is 24-3 overall this season and they are the No. 5 ranked team in the nation. The Huskies are in second place in the conference as they are one game back of No. 17 St. Johnโ€™s. UConn is 8-1 when playing on the road this season. They have lost two of their last four games with defeats to St. Johnโ€™s and Creighton.

In their last game, UConn lost 91-84 to Creighton at home on Wednesday, Feb. 18. Creighton went on a 16-7 run across five minutes late in the second half to take the lead and control of the game. The Huskies struggled to hit shots and get stops down the stretch. They shot 44% from the field and 37% from behind the 3-point line in the loss. Braylon Mullins led UConn in scoring with 25 points on 9-for-22 shooting.

Solo Ball leads the team with 14.4 points per game. Tarris Reed is grabbing a team-high 7.7 rebounds, while Silas Demary is passing for 6.5 assists per game.

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According to KenPom, Connecticut is the 13th ranked team in the nation. They are ranked 24th on offense and ranked 13th on the defensive end.

UConn is averaging 79.4 points per game, which ranks 137th in the nation. They are the 31st ranked shooting team, making 48.8% from the field. The Huskies are the 43rd ranked 3-point shooting team, making 36.8% from behind the arc.

On defense, UConn is allowing 66.1 points per game, which ranks 15th in the nation. The Huskies are allowing 40.3% from the field, which ranks 24th. They are the 30th ranked 3-point defensive team, giving up 30.4% from behind the arc.

UConn is 9-18 against the spread this season. They are 4-5 against the spread when playing on the road. The Huskies are 3-5 against the spread when they have been single-digit favorites. UConn is 5-11 against the spread when playing Big East opponents. The over is 14-13 when UConn has played this season. The over is 11-5 during conference games. The over is 6-3 during road games this year, too.

Villanova riding six-game win streak

Villanova is 21-5 overall this season. The Wildcats are in third-place in the conference with a 12-3 record. Villanova is one game back of UConn and two games out of St. Johnโ€™s. Villanova is 12-2 when playing at home this season. The Wildcats have won six straight games. The teamโ€™s last loss was a 75-67 OT defeat to UConn.

In their last game, the Wildcats defeated Xavier 92-89 in OT on the road on Tuesday, Feb. 17. Villanova led for a majority of the game and squeezed out the victory thanks to some solid defense. Villanova shot 44% from the field and 35% from behind the arc in the win. Acaden Lewis led the team with 21 points on 9-for-18 shooting.

Tyler Perkins leads the team with 13.7 points and 5.3 assists per game. Duke Brenna is the top rebounder with 10.7 boards per game.

Villanova is the 27th ranked team in the nation, according to KenPom. They have the 31st ranked offense and the 33rd ranked defense.

Villanova is averaging 78.3 points per game, which ranks 158th this season. They are the 141st ranked shooting team, making 45.9% from the field. The Wildcats are hitting 36.2% from behind the 3-point line, which ranks 67th.

On defense, Villanova is allowing 69.9 points per game, which ranks 61st. They are allowing 44.4% from the field, placing them 197th. The Wildcats are the 199th ranked 3-point defense, allowing 33.9% from behind the arc.

Villanova is 17-9 against the spread this season. They are 8-6 against the spread when playing at home this season. The Wildcats are 5-2 against the spread as an underdog. Villanova is 9-6 against the spread during conference play. The over is 16-10 when Villanova has played this season. The over is 11-4 when Villanova has played conference opponents. The over is 9-5 during home games, too.

UConn Huskies vs Villanova Wildcats Picks

UConn vs Villanova Spread Pick

  • Take Villanova to cover (5 units)ย 

UConn put together a disappointing performance against Creighton in its last game. The Huskies are struggling against some of the best teams in the conference this year. They are 2-2 in their last four games with losses to St. Johnโ€™s and the Bluejays. Villanova is surging and they are in third-place in the league. The Wildcats are on a six-game win streak, with their last loss coming in overtime to the Huskies in Storrs. Villanova is playing its best basketball at the moment, while defensive lapses are a cause for concern for UConn. The Wildcats are 5-2 against the spread as an underdog. They are also 9-6 against the spread during Big East play. The Huskies are 3-5 against the spread when they have been single-digit favorites.

Take Villanova to cover.

UConn vs Villanova Over/Under Pick

  • Take the over (5 units)ย 

The offense has been really good for both teams lately. Villanova is averaging over 78 points per game and they rank 31st in the nation in offensive efficiency. UConn is also averaging near 80 points per game. With both teams efficient on that side of the ball, a high score is expected in this one. The over is 11-4 when Villanova has played conference opponents. The over is also 9-5 during home games, too. For UConn, the over is 11-5 during conference games. The over is 6-3 during road games this year.

Take the over on Saturday.ย 

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