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Vanderbilt vs Western Kentucky, Picks and Prediction for Wednesday, November 26, 2025

By: Kevin V. Published 11/26/2025, 12:11 AM ET
Vanderbilt Commodores vs Western Kentucky Hilltoppers Picks and Prediction

The Vanderbilt Commodores play the Western Kentucky Hilltoppers on Wednesday in the opening round of the Battle for Atlantis at Imperial Arena in Nassau, Bahamas. Vanderbilt is 5-0 and beat Texas Southern 109-74 last Thursday in its most recent game. Western Kentucky is 4-0 and beat Bethel (TN) 97-67 last Tuesday. Make sure to read this in-depth Vanderbilt Commodores vs Western Kentucky Hilltoppers prediction. Elevate your game with our expert NCAAB picks for Western Kentucky Hilltoppers at Vanderbilt Commodores prediction and win big!

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Vandy has been balanced so far

The Vanderbilt Commodores are off to a very strong start offensively, averaging 103 points per game, which is 35th, while shooting 53% (15th) overall and 39.1% (38th) from long distance. At the same time, Vandy’s defense is allowing an average of 73.0 points (117th) per game, but holding opponents to 40.5% (109th) shooting overall and 35.1% (278th) from three-point land

Tyler Tanner and Duke Miles are the top two leading scorers for Vandy. Tanner averages 16.0 points per game on 54% shooting overall and 52.2% from three-point land, while Miles averages 15.4 points per game on 52% shooting overall and 40.7% from downtown. Vanderbilt has four other players averaging double figures in scoring. The Commodores average 41.2 rebounds per game, with Devin McGlockton averaging a team-best 7.4 per game. Miles is the dish leader, averaging 5.6 assists per game and the leader in steals, averaging 2.6 per contest. Tyler Harris is the rim protector with 1.4 blocks per game.

Injuries: Vanderbilt will play without George Kimble, while Frankie Collins is questionable.

Western Kentucky is tough to stop with the ball, but needs more stops on defense

The Western Kentucky Hilltoppers are 129th in scoring, averaging 90.3 points per game, on 46.3% (158th) shooting overall and 27.6% (332nd) from three-point territory. On defense, the Hilltoppers allow an average of 74.5 points (137th) per game, while holding opponents to 41.6% (130th) shooting overall and 30.8% (127th) from three-point range.

Teegan Moore and Grant Newell are Western Kentucky’s top two scorers. Moore averages 18.3 points per game on 50% shooting overall and 20% from three-point territory, while Newell averages 14.8 points per game on 48.6% shooting overall and 33.3% from long distance. Western Kentucky does not have any other players averaging double figures in scoring. The Hilltoppers grab 41.5 rebounds per game, led by Moore with an average of 6.0 boards per contest. Terrion Murdix is the dish leader, averaging 4.0 assists per game, while Armelo Boone averages a team high 3.0 steals per game, and Leeroy Odiahi is the rim protector with 0.8 blocks per game.

Injuries: Western Kentucky does not have any players on its injury report.

Western Kentucky Hilltoppers vs. Vanderbilt Commodores Pick

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Spread Pick for Western Kentucky vs. Vandy

  • Vandy  -17.5 (4 units)

Vanderbilt is off to an excellent start on offense, averaging 103 points per game, with the 15th-best field goal shooting percentage of 53%. The Commodores are beating opponents from long distance as well, making 39.1% of their three-point shots, which is 38th. The Commodores have a point differential of plus-30 and will make it hard for Western Kentucky to keep pace. Vandy is just 3-2 ATS, but in two games they failed to cover, they were 42-point and 36.5-point favorites and won by only 29 points and 35 points, respectively. Failed covers, but strong wins. Western Kentucky will have a large spread as the underdog, but will not keep pace with the way Vandy plays offensively, and is shooting only 46.3% compared to the Commodores 53%.

Over/Under Pick for Western Kentucky vs. Vandy

  • Over 168.5 (4 units)

As mentioned previously, Vanderbilt is averaging 103 points per game, surpassing 100 in four of five games, and scoring 92 in the other. The total has finished over in four of Vandy’s five games and in each of Western Kentucky’s last two games with a betting line. Vandy has an adjusted tempo per KenPom of 71.7, which is 95th, while Western Kentucky’s AdjT is 73.2 or 33rd. These two AdjTs are very conducive to high-scoring outcomes.

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