Virginia Tech Hokies vs Louisville Cardinals Picks and Predictions for Saturday, January 24, 2026

By: Cameron Ross Published 01/24/2026, 07:45 AM ET
SMU vs Louisville Prediction
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The Virginia Tech Hokies will be on the road Saturday afternoon with a game in the KFC Yum! Center in Louisville, KY, at 2:15 against the Louisville Cardinals, and we have you ready to roll with our Virginia Tech vs Louisville prediction. Virginia Tech comes into Saturday with 15 wins and five losses thus far this season. The Louisville Cardinals return home Saturday afternoon with thirteen wins and five losses this season, currently ranked #23 in the nation. Virginia Tech comes into Saturday running hot, having won three of the last four, including two in a row after a 2-point road victory against Syracuse in their last outing. Louisville has won two of the last three after a 41-point road blowout victory over Pittsburgh. Read more about this Virginia Tech vs Louisville prediction! Struggling with handicapping? Try ourย NCAAB Predictions!

Virginia Tech tries to extend winning streak

The Virginia Tech offense is averaging 82 points on 46% shooting on the floor this season. Defensively, the Hokies have been top-tier as well, holding opponents to 74.1 points per game this season through 20 games played. Offensively, Virginia Tech did just enough in their last outing, scoring 76 points, including 46 in the second half, three races, a point halftime deficit on 45% shooting from the floor. Defensively, the Hokies were the better team, giving up 74 points after 37 in each half on 43% shooting. Virginia Tech did lose the rebounding battle by two, but forced 14 turnovers to seal the victory. Ben Hammond led the way for their gene tech offense in their last outing, scoring 24 points on 10 shots in 37 minutes. Amani Hansberry and ย Neoklis Avdalas both tied for second for the starting rotation, scoring 10 points each. Tobi Lawal led the way off the Virginia Tech bench with 16 points on six shots and 30 minutes.

Amani Hansberry leads the Virginia Tech offense this season with 15.5 points and 8.6 rebounds per game. Big man Neoklis Avdalas is second on the team after 13.7 points to go along with the team-leading 5.1 rebounds. Tobi Lawal averaged 12.7 points, and Ben Hammond is averaging 12.3 points per game. Jailen Bedford is fifth on the team with 10.1 points, but has played just 19 times this season.

Key Injury Report for Virginia Tech:

  • Tyler Johnson (Out) - Undisclosed

Louisville goes for 2 in a row

Offensively, Louisville has been top tier this season, averaging 87.9 points on 47% shooting from the floor, but the Cardinals have averaged only 73 points per game over their last three losses. Defensively, Louisville is allowing 69.6 points per game this season, but has given up an average of 81 points per game during its last three losses.ย  Defensively, Louisville did the job in their last outing, giving up 59 points on 38% shooting, including 29% from the arc. Offensively, Louisville was dominant, scoring 100 points from 63% shooting, and the Cardinals knocked down 15 triples in the game. Louisville won the rebounding battle by double digits and forced 10 turnovers to seal the victory. Ryan Conwell led the way for the Louisville offense as one of five starters in double digits with 24 points on 16 shots. Jโ€™Vonne Hadley added a second-best 17 points in 31 minutes. Sananda Fru and Adrian Wooley both tied for third on the team with 12 points apiece. Isaac McKneely added a 5th-best 11 points on 8 shots in 34 minutes.

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Ryan Conwell leads the Louisville offense this season, averaging 19.8 points per game. Mikell Brown Jr. is second on the team, averaging 16.6 points. Isaac McNeely averages 12.8 points, and Jโ€™Vonne Hadley is fifth on the team, averaging 10.6 points per game. Big man Sananda Fru averages 10.8 points and leads the team, pulling in 6.9 rebounds per game. Aly Khalifa averages 3.8 points and leads Louisville, dishing out 2.9 assists per game.

Key Injury Report for Louisville:

  • Spencer Legg (Questionable) - Undisclosed
  • Khani Rooths (Questionable) - Illness
  • Mikel Brown (Questionable) - Back

Virginia Tech vs Louisville Pick

  • Virginia Tech vs Louisville Spread Pick

Both teams come into this game playing well, but Louisville is a better overall team. Look for the Cardinals to defend their home court and top-25 ranking. Take Louisville to use their edge on both sides of the ball do the job in ACC play. Louisville has a chance at one of, if not the top seed, in the ACC going into tournament time, so it will play with purpose Saturday afternoon at home against a mediocre Virginia Tech team. The Louisville Cardinals will extend their winning streak Saturday afternoon with a win and cover at home over the Virginia Tech Hokies.

  • Virginia Tech vs Louisville Over/Under Pick

Both teams scored the ball well, but Saturday will turn into a defensive slugfest. Look for the Cardinals to control the tempo with their elite defense against the attack. Expect points to come at a premium in this matchup, as both teams look to improve their ACC standings. Take Louisville Saturday afternoon to get the home win and cover, but the total will go well under the number as each team struggles to score for 40 minutes.

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