Wyoming Cowboys vs Grand Canyon Lopes Picks and Prediction for Saturday, February 21, 2026
Use Code WWWC It’s another night of Mountain West Conference action on Saturday, Feb. 21. Read our Wyoming Cowboys vs Grand Canyon Lopers prediction along with our NCAAB picks for the night. Wyoming is 14-12 and they are 5-10 in league play. The Cowboys have lost three of their last four games entering this game. Grand Canyon is 17-9 and they are in third-place in the conference with a 10-5 record. These two teams will meet with tip-off set for 8 P.M. EST.
Wyoming struggles on the road continue
Wyoming is 14-12 overall this season. The Cowboys are 5-10 when they have played in the Mountain West Conference. Wyoming is in third to last place in the league. They are 1-8 when playing on the road this season. The Cowboys have lost three of their last four games coming into this game.
In their last game, the Cowboys defeated Fresno State 92-82 at home on Tuesday, Feb. 17. Wyoming never trailed in the second half as they earned a big conference win. The Cowboys shot 54% from the field and 45% from behind the 3-point line. Nasir Meyer led the team with 22 points on 8-for-15 shooting.
Leland Walker leads the team with 14.6 points and 3.6 assists per game. Khaden Bennett is grabbing a team-high 5.1 rebounds per game.
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According to KenPom, Wyoming is the 99th ranked team in the nation. They are ranked 85th on offense and they are the 144th ranked defensive team.
Wyoming is averaging 81.1 points per game, which ranks 104th in the nation. They are the 163rd ranked shooting team, making 45.5% from the field. The Cowboys are the 203rd ranked 3-point shooting team, making 33.7% from behind the arc.
On defense, Wyoming is allowing 76.5 points per game, which ranks 217th in the nation. The Cowboys are allowing 45.8% from the field, which ranks 275th. They are the 133rd ranked 3-point defensive team, giving up 32.8% from behind the arc.
Wyoming is 11-14 against the spread this season. They are 2-7 against the spread when playing on the road. The Cowboys are 3-6 against the spread when they have been underdogs. Wyoming is 5-10 against the spread when playing Mountain West opponents. The over is 14-11 when Wyoming has played this season. The over is 8-7 during conference games. The under is 6-3 during road games this year, too.
Grand Canyon back on track with some big wins
Grand Canyon is 17-9 overall this season. The Lopers are 10-5 during the Mountain West Conference play. They are three games back of Utah State for first place in the conference. The Lopers are 11-3 when playing at home this season. They have won four of their last five games. Grand Canyon has also won five of their last six home games.
In their last game, Grand Canyon defeated San Diego State 73-63 on the road on Tuesday, Feb. 17. The Lopers were able to take over the lead in the opening minutes of the second half, and they never looked back. Grand Canyon shot 43% from the field and 37% from behind the arc. Jaden Henley led the team with 21 points on 7-for-17 shooting.
Henley leads the team with 17.5 points and 2.8 assists per game. Nana Owusu-Anane is grabbing a team-leading 8.5 rebounds per game, too.
Grand Canyon is the 58th ranked team in the nation, according to KenPom. They have the 139th ranked offense and the 22nd ranked defense.
Grand Canyon is averaging 75.2 points per game, which ranks 243rd this season. They are the 211th ranked shooting team, making 44.8% from the field. The Lopers are hitting 30.3% from behind the 3-point line, which ranks 345th.
On defense, Grand Canyon is allowing 68.6 points per game, which ranks 43rd. They are allowing 41.1% from the field, placing them 45th. The Lopers are the 75th ranked 3-point defense, allowing 31.8% from behind the arc.
Grand Canyon is 13-13 against the spread this season. They are 7-7 against the spread when playing at home this season. The Lopers are 8-8 against the spread as a favorite. Grand Canyon is 9-7 against the spread during conference play. The under is 14-12 when Grand Canyon has played this season. The under is 9-7 when Grand Canyon has played conference opponents. The total is 7-7 during home games, too.
Wyoming Cowboys vs Grand Canyon Lopers Picks
Wyoming vs Grand Canyon Spread Pick
- Take Grand Canyon to cover (5 units)
Grand Canyon continues to have one of the best home environments in the nation. The team’s defense has been fantastic this year, shutting down opposing team’s offenses on a consistent basis. The Lopers are the 22nd rank defense, facing the 85th ranked offense held by Wyoming. The problem for the Cowboys is their lack of consistency on the road. Wyoming has not been good playing away from Laramie. They are 1-8 on the road. Grand Canyon’s defense coupled with Wyoming poor play on the road will allow for easy win for the Lopers.
Take Grand Canyon to cover.
Wyoming vs Grand Canyon Over/Under Picks
Take the under (5 units)
The Lopers are the 22nd ranked defense in the nation. They are allowing 68 points per game, which ranks 43rd in the nation. Grand Canyon also plays at a fairly slow pace, too. They rank 159th in adjusted tempo. Wyoming plays even slower ranking as the 239th fastest team. The under is 9-7 when Grand Canyon has played conference opponents. The under is 6-3 during road games this year for Wyoming, too.
Take the under on Saturday.
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