Charlotte vs. East Carolina, Picks and Prediction, Saturday, November 8, 2025
Use Code WWWC Charlotte (1-7, 0-5 American) will be trying to pick up their first conference win of the season when they visit Dowdy-Ficklen Stadium on Saturday afternoon to face East Carolina (5-3, 3-1 American) at 3 PM. ET. Read on to find out which team picks up the win in this 49ers vs. Pirates prediction. Don’t get sacked this football season! Try our College Football Picks!
The 49ers are coming off a 54-20 loss to North Texas as 25.5-point underdogs. The Pirates are coming off a 45-14 win over Temple as 5.5-point favorites.
Charlotte is 2-0 in two games against East Carolina. The 49ers won last season’s meeting, 55-24.
Charlotte Trying To Snap Five-Game Losing Streak
The 49ers haven’t had much go their way this season, and they enter this game on a five-game losing streak. They last played Oct. 24 and allowed 54 points and 608 total yards to North Texas, while producing just 104 yards on the ground.
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Charlotte averages 17.5 points per game, which is 128th in the nation. They throw for 218.1 yards and rush for 106.8 points per game.
Grayson Loftis has completed 50 percent of his passes for 766 yards, five touchdowns, and four interceptions. Rod Gainey Jr. leads the team with 55 carries for 215 yards and one touchdown, while Javen Nicholas has 41 catches for 541 yards and three touchdowns.
Charlotte is giving up 37.3 points per game, which is 132nd in the country. They’re giving up 250.1 passing yards and 230.9 rushing yards per game.
Injuries: WR-Adam Hopkins (Leg), RB-CJ Stokes (Undisclosed), and TE-Joey Bearns III (Undisclosed) are questionable for this game.
ECU Going For Third Consecutive Win
The Pirates bounced back from their loss to Tulane with wins over Tulsa and Temple. They are tied for third in the AAC standings, two games behind first-placed Navy. They will try to move up the standings and become bowl eligible with a win on Saturday.
ECU averages 32.1 points per game, which is 45th in the nation. They throw for 288.9 yards and rush for 186.4 yards per game.
Katin Houser has completed 67 percent of his passes for 2,245 yards, 12 touchdowns, and five interceptions. He also has 45 rushing yards and four touchdowns. London Montgomery has 90 carries for 449 yards and four touchdowns, while Anthony Smith has 36 catches for 614 yards and three touchdowns.
East Carolina is giving up 16.8 points per game, which is 13th in the nation. They’re giving up 221.3 passing yards and 130 rushing yards per game.
Injuries: WR-Dillon Lorick (Undisclosed) is questionable for this game.
Charlotte vs. East Carolina Picks
Point Spread Pick for Charlotte vs. East Carolina
- East Carolina Pirates -28.5 (4 Units)
The Pirates have won three of their four home games, while the 49ers have lost five straight games. East Carolina has the edge here because they have one of the best offenses in the country and can beat opponents through the air and on the ground. The 49ers have one of the worst run defenses in the country and a pass defense that is almost as bad, so expect the Pirates to have their way offensively in this game.
Charlotte won’t be as successful offensively because they’re not very good offensively. They rush for less than 100 yards per game and won’t be much of a threat on the ground. Their passing game isn’t much better, with the team gaining less than 200 yards per game. The Pirates are very good against the pass and even better at defending the run, so expect them to keep Charlotte’s offense in check. Take East Carolina to cover the spread.
Over/Under Pick for Charlotte vs. East Carolina
- Over 56.5 (4 Units)
The 49ers played over the total in five of their last six games, while the Pirates played over the total in their last two games. Charlotte averages 17.5 points per game. They throw the ball 52 percent of the time with the 104th-ranked passing game in the country, and they’re facing a team that is 60th against the pass and gave up 22.3 points per game in their last three games. The Pirates average 32.1 points per game. They run the ball 56 percent of the time with the 26th-ranked ground game in the country, and they’re facing a team that is 134th against the run and gave up 42.3 points per game in their last three games. Expect these teams to score enough points to push the score over the total.
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