Coastal Carolina vs. South Carolina, Picks and Prediction, Saturday, November 22, 2025
Use Code WWWC Coastal Carolina (6-4, 5-2 Sun Belt) will be trying to keep their slim conference title hopes alive when they visit Williams-Brice Stadium on Saturday afternoon to face South Carolina (3-7, 1-7 SEC) at 4:15 PM. ET. Read on to find out which team picks up the win in this Chanticleers vs. Gamecocks prediction. Don’t get sacked this football season! Try our College Football Picks!
The Chanticleers are coming off a 45-40 loss to Georgia Southern as three-point underdogs. The Gamecocks are coming off a 31-30 loss to Texas A&M as 17-point underdogs.
South Carolina is 2-0 in two games against Coastal Carolina. The last meeting between the two teams was in 2018.
Coastal Carolina Trying To Bounce Back From Loss
The Chanticleers had their four-game winning streak snapped by the Eagles in their last game. They are second in the Sun Belt East, two games behind JMU, and will try to keep their conference title hopes alive with a win on Saturday.
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Coastal Carolina averages 25.7 points per game, which is 79th in the nation. They throw for 154.4 yards and rush for 194 yards per game.
Tad Hudson has completed 54 percent of his passes for 620 yards, three touchdowns, and four interceptions. JaVin Simpkins leads the team with 101 carries for 536 yards and two touchdowns, while Cameron Wright leads the team with 16 catches for 201 yards and one touchdown.
Coastal Carolina is giving up 29.7 points per game, which is 105th in the nation. They’re giving up 259.8 passing yards and 209.4 rushing yards per game.
Key Injuries for Coastal Carolina
QB-Samari Collier (Knee) and WR-Colton Hinton (Undisclosed) are questionable for this game. TE-Josh Humes (Undisclosed) has been ruled out.
South Carolina Trying To Snap Five-Game Losing Streak
The Gamecocks have struggled since the start of conference play and come into this game on a five-game losing streak. They blew the biggest lead in school history in their loss to the Aggies in their last game and will try to get past the disappointing loss with a win on Saturday.
South Carolina averages 20.7 points per game, which is 115th in the nation. They throw for 200.7 yards and rush for 102.8 yards per game.
LaNorris Sellers has completed 60 percent of his passes for 1,782 yards, nine touchdowns, and six interceptions. He also has 186 rushing yards and three touchdowns. Rahsul Faison leads the team with 86 carries for 376 yards and three touchdowns, while Nyck Harbor leads the team with 24 catches for 503 yards and five touchdowns.
South Carolina is giving up 23 points per game, which is 53rd in the nation. They’re giving up 216.2 passing yards and 153.9 rushing yards per game.
Key Injuries for South Carolina:
WR-Nyck Harbor (Undisclosed), WR-Jordan Gidron (Undisclosed), WR-Lex Cyrus (Undisclosed), and TE-Michael Smith (Undisclosed) are questionable for this game.
Coastal Carolina vs. South Carolina Picks
Point Spread Pick for Coastal Carolina vs. South Carolina
- South Carolina Gamecocks -24.5 (4 Units)
The Gamecocks have the edge here because they’re the more talented team. They don’t have a high-scoring offense, but they’ve been able to throw the ball effectively, which will be a problem for the Chanticleers, who have one of the worst pass defenses in the country. They will also be able to run the ball against a defense that gives up more than 205 yards per game on the ground, so expect the Gamecocks to have their way offensively in this game.
The Chanticleers will have a hard time keeping up in this game because they’re one-dimensional offensively, with one of the worst passing games in the country and a decent ground game. The Gamecocks are very good defensively, and they don’t give up a lot of yards on the ground, so expect them to keep Coastal Carolina’s offense in check. Take South Carolina to cover the spread.
Over/Under Pick for Coastal Carolina vs. South Carolina
- Over 50.5 (4 Units)
Coastal Carolina averages 25.7 points per game. They run the ball 57 percent of the time with the 31st-ranked ground game in the country, and they’re facing a team that is 68th against the run and is giving up 23 points per game. South Carolina averages 20.7 points per game. They run the ball 52 percent of the time with the 125th-ranked ground defense in the nation, and they’re facing a team that is giving up 29.7 points per game. Expect these teams to score enough points to push the score over the total. The Chanticleers and Roadrunners played over the total in their two meetings.
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