Eastern Michigan vs. Central Michigan Picks and Prediction, Saturday, September 27, 2025

By: Liam Keating Published 09/25/2025, 04:46 PM ET
Eastern Michigan vs Central Michigan prediction
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It’s a battle between two MAC schools in the great state of Michigan on Saturday, Sept. 27. Read our Eastern Michigan vs Central Michigan prediction along with our other NCAAF Betting Picks! Eastern Michigan 1-3 this season and they snapped an 8-game losing streak in their last time out. Central Michigan is 2-2 and they secured a big win at home in their last outing. These two teams will meet with kick-off set for 1 P.M. EST.

Eastern Michigan snaps losing streak

Eastern Michigan is 1-3 overall this season. They started the season losing three straight with defeats to Texas State and Kentucky on the road. They also suffered an embarrassing home loss to FCS Long Island in their home opener. The Eagles were able to bounce back in their last game, snapping an 8-game losing streak.

In their last game, Eastern Michigan defeated Louisiana 34-31 at home on Saturday, Sept. 20. The Eagles used a 49-yard field goal from Rudy Kissinger to seal the win with three seconds  left in the game. Eastern Michigan and Louisiana traded blows, with the Ragin' Cajuns’ tying the game with less than a minute. The Eagles erased a 7-0 deficit and a 3-point deficit in the second half. Quarterback Noah Kim threw for 226 yards on 21-for-31 passing with a touchdown and an interception. It was a big game for running back Dontae McMillan, who rushed for 126 yards and 19 carries.

Kim, who is a Michigan State and Coastal Carolina transfer, has thrown for 993 yards and has completed 64% of his passes. He has tossed five touchdowns and two picks so far this year. McMillan has been one of the team’s top weapons, rushing for 345 total yards and a touchdown.

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On defense, Eastern Michigan is led in tackles by Bryce Llewellyn with 29. The defense has only secured two sacks total this year. They have also forced only two turnovers this season, too.

“Our football team, we are in good shape. It is right there for us, our guys are all in, we’re together — and those [positive] moments, they haven’t happened yet. But they’re going to — we have the pieces,” Eastern Michigan head coach Chris Creighton said. 

Eastern Michigan is averaging 26.8 points per game, which ranks 84th in the nation. They are the 54th-ranked passing attack with 248.3 yards per game through the air. The Eagles also rank 88th in rushing the bal,l going for 144.8 yards per game on the ground.

On defense, Eastern Michigan is allowing 39.8 points per game, which ranks 132nd. They are the 136th-ranked rush defense, giving up 272 yards per game. The Eagles rank 92nd in defending the pass, surrendering 232 yards.

Eastern Michigan is 2-2 against the spread this season. They have covered in back-to-back games against Louisiana and Kentucky. The Eagles are 2-1 against the spread as an underdog. They are also 0-1 against the spread as a favorite. The over is 3-1 when Eastern Michigan has played this season. The over is 2-0 when the total has been set at 54 points or less.

Central Michigan ready to defend home turf

Central Michigan is 2-2 this season. They opened their season with a 16-14 win over San Jose State. The Chippewas followed it with big defeats to Pitt and Michigan, which both came on the road.

In their last game, Central Michigan defeated Wagner 49-10 for their home opener on Saturday, Sept. 20. It was a big win for the Chippewas, who scored 49 of the game’s first 52 points. The offense accumulated 507 yards while their defense suppressed the Seahawks to just 115 yards of offense. Quarterback Joe Labas threw for 241 yards on 12-for-14 passing and three touchdowns. Trey Cornist rushed for a team-high 52 yards, too.

Labas has thrown for 422 yards and has completed 69% of his passes. He has thrown four touchdowns and a pick. Three different running backs have rushed for over 100 yards total this season.

On defense, Central Michigan is led in tackles by Jordan Kwiatkowski with 22 tackles. Michael Heldman has been great with three total sacks to lead the team. The Chippewas have a total of five sacks this season. They have also forced seven turnovers on the year.

"You look at his head-coaching track record and tenure, he has had incredible success at each stop he has had," Central Michigan head coach Matt Drinkall said of Eastern Michigan’s Chris Creighton. “"He's able to find ways to be super successful and program-build, regardless if it's non-scholarship or whatever level, he's done such a good job.

Central Michigan is averaging 21.3 points per game, which ranks 106th. They are the 122nd-ranked passing team, going for 156 yards per game through the air. The Chippewas are rushing for 147 yards per game on the ground, placing them 86th.

On defense, Central Michigan is allowing 33 points per game, placing them 122nd. They are the 90th-ranked pass defense, giving up 231 yards through the air. The Chippewas are the 95th-ranked rush defense, giving up 163 yards per game.

Central Michigan is 2-2 against the spread this season. They covered as a 28-point favorite against Wagner. They are 1-2 against the spread when they have been underdogs this year. The over is 3-1 when Central Michigan has played. The over is 3-0 when the total has been set at 49 points or fewer.

Eastern Michigan vs Central Michigan Picks

Eastern Michigan vs Central Michigan Spread Pick

  • Central Michigan -6.5 (5 units)

It’s a battle between two Michigan MAC teams in this game on Saturday. The Chippewas are coming off of a big win, and I think they will continue to ride that momentum with a win over Eastern Michigan. Central Michigan’s defense has looked strong despite playing tough opponents. They have forced turnovers and rushed opposing quarterbacks well. If their offense can find a way to rush the ball, they will find success. Eastern Michigan’s defense is one of the worst in the nation. They are allowing nearly 40 points per game as they allow chunk plays easily. Eastern Michigan’s offense is simply not good enough if this game turns into a shootout. The Eagles just snapped an 8-game losing streak thanks to a late field goal, but the Chippewas will defend their home stadium.

Take Central Michigan to cover. 

Eastern Michigan vs Central Michigan Over/Under Pick

  • Under 54 (5 units) 

Defense will be key in this game, and Central Michigan has shown that it can shine on this side of the ball. The Chippewas have forced seven turnovers and secured five sacks on the season. They can dominate an Eastern Michigan team that ranks in the bottom half of offensive categories. Central Michigan’s offense is also averaging 21.3 points per game, which won’t be good enough to have a high-scoring game. Expect drives to stall and turnovers to occur.

Take the under on Saturday. 

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