Iowa State vs. Oklahoma State, Odds, Preview, Picks and Prediction for Saturday, November 29, 2025
Week 14 of the college football season rolls on with a battle of Big 12 squads looking to earn a conference victory as the Iowa State Cyclones travel to take on the Oklahoma State Cowboys Saturday afternoon and we have you covered with our Iowa State vs. Oklahoma State prediction. Iowa State comes in off 38-14 win over Kansas at home last Saturday, covering the line as a three-point favorite, in their previous contest. Oklahoma State fell 17-14 at UCF in their previous game last Saturday, covering the line as a 13.5-point underdog. In the all-time series between the teams, the Cowboys own a 34-21-3 advantage but the Cyclones picked up a 34-27 home win in the most recent matchup September 23, 2023. Read more about this Iowa State vs. Oklahoma State prediction! Don’t get penalized! Increase your bankroll with our NCAAF Betting Picks!
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Cyclones Seeking to Earn Third Straight Win
Iowa State won their second straight after a four-game skid as they took down Kansas at home in their previous game. The Cyclones improved to 7-4 on the season and stand 4-4 in the Big 12 on the season. Against Kansas, Iowa State led 7-0 after the opening quarter and 17-0 at the half en route to the victory. The Cyclones never let the Jayhawks closer than 10 the rest of the way as they took care of business at home. Iowa State owned a 462-323 advantage in total offense, picked up 25 first downs while allowing 17, dominated time of possession by a 39:08 to 20:52 margin, and forced the game’s lone turnover.
For the year, the Cyclones are 66th in the nation in passing offense with 231.3 yards per game. The Cyclones are tied for 58th in rushing offense as they grind out 169.4 yards per contest on the ground. Iowa State is 66th in the FBS in scoring offense by putting up 28.1 points per game. The Cyclones stand 33rd in the country in scoring defense by allowing 20.8 points per contest. Rocco Becht is 196 of 320 passing for 2,471 yards with 15 touchdowns and nine interceptions while adding 88 yards plus eight scores on the ground. Alex Manske (four of five, 28 yards, 31 rush yards, TD) and Connor Moberly (zero of one, 29 rush yards) are next on the depth chart. The Cyclones have a three-headed ground attack with Abu Sama III (129 carries, 645 yards, four TD) and Carson Hansen (163 carries, 841 yards, six TD) and Dylan Lee (25 carries, 117 yards, TD) all effective when they get the ball. Benjamin Brahmer leads the team with 36 receptions for 422 yards and six scores from the tight end spot. Brett Eskildsen (29 catches, 507 yards, five TD), Chase Sowell (28 grabs, 446 yards, TD), Xavier Townsend (18 receptions, 243 yards) and tight end Gabe Burkle (26 catches, 302 yards, TD) are each over 200 receiving yards this season. Kyle Konrardy is 17 of 19 on extra point attempts and 12 of 16 field goal attempts with a long of 63 this season. Chase Smith is 12 of 12 on extra point attempts and two of three on field goal attempts with a long of 38.
Key Injury Report for Iowa State:
- Tight end Gabe Burkle (leg) is out.
- Wide receiver Xavier Townsend (undisclosed) is out.
Oklahoma State Looking to Salvage Season Finale
Oklahoma State trudges on through a lost season as they suffered a 10th straight loss when they fell at UCF on the road. The Cowboys fell to 1-10 overall on the season and are in the basement of the Big 12 with a 0-8 conference mark. Against UCF, Oklahoma State led 7-0 after the opening quarter and 14-0 at the half only to see it slip away. The Cowboys were up 14-7 after three quarters but were outscored 10-0 in the fourth quarter, giving up the winning field goal with 57 seconds remaining, to wind up with the loss. Oklahoma State was outgained 396-228 in total offense, gave up 16 first downs while recording 12 and lost time of possession by a 31:28 to 28:32 margin. The Cowboys did force two turnovers while committing one in the loss.
On the season, Oklahoma State enters this game 118th in the FBS in passing offense with 171.5 yards per contest and 101st in rushing offense as they grind out 126.6 yards per game. The Cowboys are 134th in scoring offense with an average of 14.3 points per contest and 127th in scoring defense by allowing an average of 34.5 points a game. Zane Flores is the man under center as he is 136 of 232 passing for 1,288 yards with three touchdowns against six interceptions plus 132 rushing yards and two scores. Sam Jackson V (35 of 66, 358 yards, TD, two INT, rush TD), Hauss Hejny (five of 10, 96 yards, TD, 27 rush yards, TD), Noah Walters (six of 14, 72 yards, TD, nine rush yards) and Banks Bowen (three of five, four yards, 28 rush yards) have seen action as well. Rodney Fields Jr. leads the team on the ground with 124 carries for 614 yards and a score on the year. Trent Howland (49 carries, 206 yards, two TD), Kalib Hicks (44 carries, 128 yards) and Sesi Vailahi (41 carries, 150 yards, two TD) are also in the mix on the ground. Gavin Freeman leads the team with 46 receptions for 435 yards and four scores on the year. Shemar Rigby (20 catches, 299 yards, TD), Terrill Davis (24 grabs, 316 yards) and Fields Jr. (28 catches, 276 yards, TD) are solid secondary options in the passing game. Logan Ward is 16 of 16 on extra points and 13 of 18 on field goal attempts with a long of 49 this season.
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Key Injury Report for Oklahoma State:
- Running back Rodney Fields Jr. (undisclosed) is questionable.
Iowa State vs. Oklahoma State Pick
Iowa State vs. Oklahoma State Spread Pick
- Iowa State -13 (4 units)
Iowa State is missing a pair of prime targets in the passing game, but facing an Oklahoma State squad with 10 straight losses, even in Stillwater, shouldn’t pose a massive threat. The Cyclones have bounced back from four straight defeats by winning two straight. Iowa State is capable of grinding out possessions and making things difficult for opposing teams. The Cowboys have struggled all season long on both sides of the ball and there’s little reason to think things will change here. Oklahoma State is going nowhere, and they are ready to turn the page to next year. Take Iowa State to earn a third straight win.
Iowa State vs. Oklahoma State Over/Under Pick
- Under 46.5 (4 units)
Iowa State has stayed under the number in seven of their 11 games on the season. The Cyclones kept their first five opponents to 21 points or less before allowing at least 24 points in each of their four losses. They rebounded by holding TCU and Kansas to 17 and 14 points, respectively. Oklahoma State has seen the under post a 6-5 mark on the season. The Cowboys have given up at least 38 points in seven games on the year. Oklahoma State has struggled offensively, failing to score more than 20 points eight times in 11 games. The Cowboys don’t do a ton on offense, but Iowa State is content to grind the clock with a lead to keep this game under the total.
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