NC State Wolfpack vs. Pitt Panthers Picks and Prediction for Saturday, October 25, 2025

By: Chris King Published 10/23/2025, 09:36 PM ET
NC State vs. Pitt Prediction
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A pair of ACC programs take to the field looking to pick up a win in the Steel City when the NC State Wolfpack travel to face the Pitt Panthers Saturday afternoon and we have you covered with our NC State vs. Pitt prediction. NC State comes off a bye last week. The Wolfpack was hammered 36-7 by #16 Notre Dame on the road, failing to cover the line as a 24-point underdog, in their previous contest on October 11. Pitt dropped Syracuse 30-13 on the road last Saturday, covering the line as a 10-point favorite in their previous contest. In the all-time series between the teams, the teams are even at 5-5-1, though the Wolfpack has won three straight meetings, including a 30-29 road win in the most recent meeting on October 3, 2020. Read more about this NC State vs. Pitt prediction! Donโ€™t get penalized! Increase your bankroll with our NCAAF Betting Picks!

NC State Hoping Bye Week Helps Right the Ship

NC State had a bye last week and comes in with three losses in their previous four games as they were clubbed by #16 Notre Dame in their previous contest on October 11. The Wolfpack dropped to 4-3 overall and stands 1-2 in ACC action on the year entering this game. Against Notre Dame, NC State was tied at seven in the opening 90 seconds of the second quarter and gave up a field goal on the final play of the first half to trail 10-7 at intermission. The Wolfpack was blanked in the second half while giving up 26 points to turn the game into a rout. NC State was trounced 485-233 in total offense, allowed 24 first downs while picking up 12, lost time of possession by a 31:13 to 28:47 margin and turned the ball over three times while forcing a pair of takeaways in the loss.

On the season, the Wolfpack is 35th in the nation in passing offense as they average 268 yards per game through the air this season. NC State stands 76th in the country in rushing offense with an average of 149 yards per contest. The Wolfpack is 58th in the FBS in scoring offense with 30 points per contest. NC State is 88th in the country in scoring defense, as they allow an average of 26.6 points per game. CJ Bailey is 155 of 215 passing for 1,846 yards with 14 touchdowns against seven interceptions while adding 64 yards and three scores on the ground. Lex Thomas (two of six, 18 yards) and Will Wilson (three of five, 16 yards, INT, 29 rush yards, three TD) have seen limited action. Hollywood Smothers leads the team with 112 carries for 739 yards and five scores to lead the run game. Jayden Scott (44 carries, 211 yards, three TD) is the second back in the system. Tight end Justin Joly leads the team with 30 receptions for 264 yards and three scores on the year. Terrell Anderson (24 catches, 445 yards, four TD), Wesley Grimes (14 grabs, 243 yards, TD), Noah Rogers (15 catches, 235 yards, TD), Keenan Jackson (20 receptions, 214 yards, two TD), Teddy Hoffman (13 grabs, 155 yards) and Smothers (25 receptions, 145 yards, TD) are solid targets in the passing game. Kanoah Vinesett is 24 of 25 on extra point attempts and two of three on field goal attempts with a long of 38 this season. Nick Konieczynski is three of three on extra point attempts and one of three on field goal attempts with a long of 29 this year.

Anderson (undisclosed) is questionable for this contest.

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Panthers Seek to Keep Rolling

Pitt won their third straight game as they went on the road and took down Syracuse last week. The Panthers improved to 5-2 overall on the year and stand tied for fourth in the ACC with a 3-1 mark in conference play. Against Syracuse, Pitt was even at seven after the opening quarter and led just 10-7 just before the half, before Kenny Johnson returned a punt 66 yards for a score with two seconds to play. That gave Pitt a 17-7 lead at the half and never let Syracuse closer than that the rest of the way. The Panthers held a 255-212 advantage in total offense, recorded 16 first downs while allowing 13 and forced three turnovers while committing one to offset a 30:02 to 29:58 disadvantage in time of possession in the game.

This season, the Panthers are 20th in the nation in passing offense with an average of 285.1 yards per game, while they are 109th in rushing offense with 121.4 yards per contest. Pitt is 13th in the FBS in scoring offense with an average of 38.4 points per game, while they are 39th in scoring defense by giving up 20.3 points a contest. Eli Holstein is 74 of 118 passing for 1,058 yards with 11 touchdowns against five interceptions. He is fifth on the team on the ground with 83 rushing yards plus a score. Mason Heintschel (67 of 98, 820 yards, six TD, three INT, 115 rush yards, TD) and Cole Gonzales (11 of 22, 118 yards, TD, INT, one rush yard) have also seen action, with Heintschel the current starter after displacing Holstein ahead of the Boston College game on October 4. Desmond Reid is the teamโ€™s leading rusher with 42 carries for 225 yards and a score on the ground. Jaโ€™Kyrian Turner (53 carries, 222 yards, four TD) and Juelz Goff (53 carries, 189 yards, four TD) are next in line with the run game. Raphael Williams Jr. leads the team with 27 receptions for 426 yards and four scores on the year. Kenny Johnson (26 catches, 390 yards, two TD), Reid (14 grabs, 226 yards, two TD), Cataurus Hicks (13 receptions, 216 yards, three TD) and Bryce Yates (six catches,165 yards, TD) have each gone over the 150-yard mark this season in receiving yards. Trey Butkowski has connected on 30 of 31 extra point attempts and 15 of 16 field goals with a long of 47 on the year.

NC State vs. Pitt Prediction

Spread Pick for NC State vs. Pitt

  • Pitt -6.5 (4 units)

Pitt has rebounded with three straight wins as Heintschel has sparked their offense to 112 points in that span after taking over for Holstein. The Panthers are clicking right now and are at home, where they are 3-1 on the year. NC State started the year 3-0 but their lone win in the last four games came over a FCS program in Campbell. The Wolfpack has committed 10 turnovers and they have been susceptible to giving up plays through the air. NC State gives up an average of 257.3 yards per game and 10 scores through the air on the year. Pitt has been excellent with Heintschel running the offense and with NC State trending in the wrong direction, you have to give the Panthers the upper hand in this contest.

Over/Under Pick for NC State vs. Pitt

  • Over 54.5 (4 units)

NC State has seen the over post a 4-3 mark in their seven games on the year. The Wolfpack has scored at least 33 points four times this season but their two lowest point totals have come in the last three games. NC State has been good offensively, going over the total in two of their three road tilts on the year. Pitt has been firing on all cylinders under Heintschelโ€™s leadership and the Panthers are 13th in the nation in scoring offense this season. The Panthers are good offensively and the Wolfpack has coughed up an average of 35 points per game on the road this season. Look for this game to wind up over the total.

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