Oklahoma vs Michigan Picks and Prediction for Saturday September 12 2026

On Saturday, the eleventh-ranked Oklahoma Sooners (1-0) face off against the Michigan Wolverines (1-0) at Michigan Stadium in Ann Arbor, Michigan. Get involved in the action with our free College Football picks.

Oklahoma vs. Michigan Game Information

• September 12, 2026
• 12:00 PM EST
• Michigan Stadium
• FOX

Michigan Form & Recent Results

Michigan heads into this matchup with a win already under its belt, but it certainly did not come without drama. The Wolverines opened their season with a narrow 13-12 victory at home over Western Michigan, and the finish was about as chaotic as it gets. The game initially appeared to be over in favor of Western Michigan, but after a review or clock adjustment, one second was put back on the clock. That small window was all Michigan needed, as the Wolverines pulled off a last-second Hail Mary touchdown to escape with a stunning win. Quarterback Bryce Underwood had an up-and-down performance in the opener, completing 12 of his 22 pass attempts for 170 yards, one touchdown, and one interception. He also made plays with his legs, carrying the ball nine times for 47 rushing yards, which gave Michigan some much-needed production on the ground.

One of the biggest bright spots for the Wolverines was wide receiver JJ Buchanan, who put together a strong performance with six catches for 126 yards and the game-changing touchdown. Defensively, linebacker Troy Bowles led the way with 12 tackles, helping Michigan stay within striking distance throughout the afternoon. As a team, the Wolverines finished with 276 total yards of offense and converted their only fourth-down attempt, which proved important in such a tight contest. Now, after surviving a game that felt equal parts miraculous and controversial, Michigan will try to build on that momentum. The challenge will be much tougher this week, as the Wolverines welcome the 11th-ranked Oklahoma Sooners to Ann Arbor on Saturday afternoon. If Michigan wants to remain unbeaten, it will likely need a cleaner, more complete performance, and maybe just a little more late-game magic.

Oklahoma Form & Recent Results

Oklahoma comes into this matchup sitting at No. 11 in the latest AP Poll, and the Sooners should be feeling pretty confident after getting their season started in dominant fashion. They opened the year at home last weekend with a 51-0 shutout victory over UTEP, a game where they controlled things from start to finish and never really gave the Miners much of a chance to settle in. Quarterback John Mateer put together an efficient performance, completing 11 of his 17 pass attempts and throwing for three touchdowns. The running game also played a big role, with Lloyd Avant carrying the ball 15 times for 79 yards and a touchdown. Through the air, Isaiah Sategna III stood out as one of the top playmakers for the Sooners, finishing with four catches for 76 yards and a touchdown. Defensively, Oklahoma was just as impressive, and linebacker Owen Heinecke helped lead the way with seven tackles in the shutout effort.

The Sooners put together a strong all-around performance in that opener. Oklahoma finished with 401 total yards of offense, picked up 18 first downs, and converted six of its 11 third-down opportunities, which helped keep drives alive and allowed the offense to stay in rhythm. The Sooners did turn the ball over once, but it didn’t end up hurting them in a game they had firmly under control. They also held the ball for right around half of the game, showing balance and the ability to manage the tempo. Now, Oklahoma heads to Ann Arbor with plenty of momentum and a chance to make an early statement on the road. Facing Michigan is never an easy task, especially in that environment, but the Sooners will be looking to build off their impressive opener and hand the Wolverines their first loss of the season.

Key Stats

• OU’s John Mateer this season: 11-for-17, 3 TD’s
• MICH’s Bryce Underwood this season: 12-for-22, 1 TD, 1 INT

Betting Odds & Market Overview:

• OU -5.5; O/U 43.5

Oklahoma vs. Michigan Picks and Prediction

Michigan is hoping to move past the controversy surrounding last week's win, and a home upset over No. 11 Oklahoma would be a strong way to do it. The Sooners, meanwhile, are trying to open the season 2-0, hand Michigan its first loss, and avoid becoming the upset victim. Final Score Prediction, Oklahoma Sooners win and cover the spread, 29-23.