Rice vs. Charlotte, Picks and Prediction, Thursday, September 18, 2025
Use Code WWWC Rice (2-1, 0-0 American) will be trying to kick off conference play with a win when they visit Jerry Richardson Stadium on Thursday night to face Charlotte (1-2, 0-0 American) at 7:30 PM. ET. Read on to find out which team picks up the win in this Owls vs. 49ers prediction.
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The Owls are coming off a 38-17 win over Prairie View as 29.5-point favorites. The 49ers are coming off a 42-35 win over Monmouth as 2.5-point favorites.
Charlotte and Rice split their six meetings. The 49ers won last season’s meeting, 21-20.
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Rice Going For Third Win In Four Games
The Owls bounced back from their loss to Houston with a win over Prairie View in their last game. They will try to keep the momentum going and pick up their third win in their last four games when they play on Thursday.
Rice averages 24.3 points per game. They’re throwing for 70 yards and rushing for 243.3 yards per game.
Chase Jenkins has completed 73 percent of his passes for 182 yards, one touchdown, and one interception this season. He also has 47 carries for 144 yards and two touchdowns. Quinton Jackson leads the team with 46 carries for 213 yards and two touchdowns, while Drayden Dickmann has 11 catches for 84 yards.
Rice is giving up 21.3 points per game. They are giving up 138 passing yards and 177 rushing yards per game.
Charlotte Going For Second Consecutive Win
The 49ers snapped their two-game losing streak with a win over Monmouth in their last game to pick up their first win of the season. They will try to keep the momentum going and pick up their second straight win when they play on Thursday.
Charlotte averages 18.7 points per game. They are throwing for 258 yards and rushing for 92.7 yards per game.
Conner Harrell has completed 68 percent of his passes for 664 yards, four touchdowns, and two interceptions this season. He also has 25 carries for 45 yards and two touchdowns. CJ Stokes leads the team with 32 carries for 96 yards, while E. Jai Mason leads the team with 16 catches for 284 yards and three touchdowns.
Charlotte is giving up 29.7 points per game. They are giving up 165 rushing yards and 279.5 passing yards per game.
Rice vs. Charlotte Pick
Point Spread Pick for Rice vs. Charlotte
- Rice Owls -2.5 (4 Units)
The Owls have won two of their three games, while the 49ers have lost two of their three games. Rice has the edge here because they have one of the best running games in the country, and they’re facing a team that has been unable to stop the run this season and is giving up more than 165 yards per game on the ground, so expect the Owls to keep the ball on the ground until the 49ers prove they can stop it.
Charlotte will struggle offensively in this game because they have one of the worst running games in the country and love to throw the ball. Their inability to run the ball makes them one-dimensional and will allow the Owls to keep pressure on Harrell and force him to make costly mistakes. Take Rice to cover the spread.
Over/Under Pick for Rice vs. Charlotte
- Over 42 (4 Units)
The Owls played over the total in three of their last four games, while the 49ers played over the total in three of their last six games. Rice averages 24.3 points per game. They have the 14th-best ground attack in the country and they’re facing a team that is 89th against the run and is giving up 29.7 points per game. The Owls will do the heavy lifting, but these teams will score enough points to push the score over the total.
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