San Jose State vs. Stanford Picks and Prediction, Saturday, September 27, 2025

By: Liam Keating Published 09/25/2025, 05:56 PM ET
San Jose State vs Stanford prediction
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It’s another strong slate of college football games on Saturday, Sept. 27. Read our San Jose State vs Stanford prediction along with our other NCAAF Betting Picks! The Spartans are 1-2 this season and are coming off of their first win of the season. Stanford is 1-3 and they are looking for their first 2-0 home start since 2018. These two teams will meet with kick-off set for 7:30 P.M. EST.

San Jose State looking for a big road win

San Jose State is 1-2 this season. They opened the season with a 16-14 home loss to Central Michigan. The Spartans followed it with a 38-7 loss to No. 7 Texas on the road, but they were able to cover the spread in that game.

In their last game, San Jose State defeated Idaho 31-28 on Saturday, Sept. 20. The Spartans used a Denis Lynch 48-yard field goal to win the game in the final seconds. San Jose State never led in the game before that moment as they trailed 14-0 in the first half. Quarterback Walker Eget threw for 222 yards on 13-for-21 passing and a touchdown. Running back Jabari Bates enjoyed a big game, leading the team with 131 rushing yards and a score.

Eget has thrown for 714 passing yards while completing 54% of his throws. He has tossed three touchdowns and three picks this year. It’s been a big season for wide receiver Danny Scudero, who leads the team with 379 receiving yards on 22 catches and a touchdown.

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On defense, San Jose State is led in tackles by linebacker Jordan Pollard. The Spartans have struggled to pressure the quarterback, as they have two total sacks this year. They have also forced only three turnovers.

San Jose State is averaging 17.3 points per game, which ranks 124th in the country. They are the 62nd passing offense as they are averaging 239.2 yards per game through the air. The Spartans are the 106th-ranked rush offense as they are averaging 119.3 yards per game on the ground.

On defense, the Spartans are allowing 27.3 points per game, which ranks 97th. They are the 84th-ranked pass defense, giving up 221.3 yards per game through the air. San Jose State is allowing 181 rushing yards per game, ranking them 116th.

San Jose State is 1-2 against the spread this season. They are 0-2 against the spread when they have been favored this year. They covered as a 37-point underdog against Texas, too. The under is 2-1 when San Jose State has played this year, too.

Stanford finally back at home

Stanford is 1-3 overall this season. All three of their losses this season have come on the road. They opened the year with defeats to Hawai’i and BYU. The Cardinal followed it with a 10-point win over Boston College at home.

In their last game, Stanford lost 48-20 to Virginia on the road on Saturday, Sept. 20. The Cardinal allowed Virginia to score four straight touchdowns on their first four drives of the game. Stanford allowed 594 total yards of offense as the defense could not slow down Virginia.

Stanford’s offense accumulated 323 yards of offense as they went 6-for-14 on third down. Stanford couldn’t finish drives in the defeat. Quarterback Ben Gulbranson threw or 286 yards on 20-for-29 and two touchdowns. Wide receiver Bryce Farrell caught four passes for 135 yards and a touchdown in the game.

Gulbranson threw for 723 yards and has completed 57.5% of his passes. He has thrown three touchdowns and three interceptions. Running back Micah Ford leads the rushing attack with 335 yards and tree touchdowns.

On defense, Stanford linebacker Matt Rose leads the team with 39 tackles, which is 16 more than anyone else. The defense has forced four turnovers on the season so far. “

They've got a bunch of returning starters," Stanford head coach Frank Reich said. "Five or six returning starters. Their linebackers are really good, aggressive players. Number one, number four, guys that kind of pop out on the film. Up front, they're all really active and physical players on their defensive line. And then the secondary, just have good, solid players. You see them, they've got good schemes. They play it well. Their defensive coordinator, coach [Derrick] Odum is a very, very accomplished defensive coordinator, very successful defensive coordinator, has an impressive resume. They put a lot of good stuff on tape. It's well conceived, well executed and well coached."

Stanford is averaging 18.3 points per game, placing them 119th in the nation. They are the 110th-ranked passing offense, averaging 180.8 passing yards per game. The Cardinal are also averaging 111 rushing yards per gam,e placing them 116th.

On defense, the Cardinal are allowing 29.5 points per game, ranking 110th. They are the 120th-ranked pass defense, giving up 275.5 yards per game through the air. Stanford is the 56th-ranked rush defense, giving up 128.8 yards on the ground.

Stanford is 1-3 against the spread this season. They have been underdogs in every game this season. In their lone home game, the Cardinal covered as a 14-point game against the Boston College. The total is 2-2 when Stanford has played this season.

San Jose State vs Stanford Picks

San Jose State vs Stanford Spread Pick

  • Stanford -3 (5 units) 

Stanford will be looking for their first 2-0 start at home since 2018. It’s a big game for both teams as they look to continue moving in the right direction. It’s been a tough start for both teams as they are leaking points and struggling to score in the red zone. San Jose State needed a late comeback to secure a win over Idaho last week. Stanford was dominated by Virginia in their last game. The difference is going to come down to whose defense will finally show up. San Jose State and Stanford are both towards the bottom in all defensive stats. Stanford quarterback Ben Gulbranson has looked good in the past few games, and he will be key in this one. If he produces, Stanford should come away with the win in a close game.

Take Stanford to cover. 

San Jose State vs Stanford Over/Under Pick

  • Over 49.5 (5 units)

The two defenses have struggled this season. They are leaking points to whoever the opponent in this year with both teams ranked towards the bottom third of points allowed per game. The offenses haven’t been lighting up scoreboards, but the two defenses can’t rush the quarterback and can’t forced turnovers allowing chunk plays to occur.

Take the over on Saturday. 

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