South Florida (USF) vs. North Texas, Picks and Prediction, Friday, October 10, 2025

By: Bosun Akinpelu Published 10/09/2025, 01:04 PM ET
Bulls vs. Mean Green Prediction
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South Florida (4-1, 1-0 American) will be trying to pick up their second road win of the season when they visit DATCU Stadium on Friday night to face North Texas (5-0, 1-0 American) at 7:30 PM. ET. Read on to find out which team picks up the win in this Bulls vs. Mean Green prediction. Don’t get sacked this football season! Try our College Football Picks!

The Bulls are coming off a 54-26 win over Charlotte as 28-point favorites. The Mean Green are coming off a 36-22 win over South Alabama as 13-point favorites.

South Florida is 2-0 in two games against North Texas. The last meeting between the two teams was in 2002.

South Florida Going For Third Consecutive Win

The Bulls bounced back from their loss to Miami-Florida (49-12) on Sept. 13 with wins over FCS South Carolina State and Charlotte. They amassed 117 points in those two games.

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USF averages 44.2 points per game, which is 10th in the country. They throw for 257.2 yards and rush for 188.8 yards per game.

Quarterback Byrum Brown has completed 61 percent of his passes for 1,194 yards, 10 touchdowns, and four interceptions. He also leads the team with 64 carries for 282 yards and three touchdowns, while Chas Nimrod leads the team with 19 catches for 421 yards and three touchdowns. Brown had 211 yards passing and 162 yards rushing against Charlotte, including four passing TDs (2 picks) and one rushing score.

USF is giving up 22.4 points per game, which is 60th in the country. They are giving up 249.5 passing yards and 147.5 rushing yards per game.

They have some depth issues at running back with Cartevious North (166 yds, 2 TDs) and Tray Kinkle questionable with undisclosed injuries.

North Texas Going For Sixth Consecutive Win

The Mean Green are off to one of the best starts in school history and enter this game on a five-game winning streak. They beat South Alabama 36-22 on Sept. 27 at home in their last game. They also beat Army on the road in overtime 45-38 in their only conference win.

North Texas averages 44.8 points per game, which is ninth in the country. They throw for 256.6 yards and rush for 180.4 yards per game.

Drew Mestermaker has completed 68 percent of his passes for 1,247 yards and 11 touchdowns. He also has 65 rushing yards and two touchdowns. He struggled with accuracy in his last game, completing 14 of 26 for 234 yards with one TD and no picks against USA. RB Caleb Hawkins had an incredible game with 140 yards rushing and two scores, along with two catches for 78 yards and a touchdown  Mackenzie McGill leads the team with 63 carries for 318 yards and four touchdowns, while Miles Coleman leads the team with 23 carries for 219 yards. Hawkins adds 307 yards rushing on 7.3 yards per carry with seven TDs.

North Texas is giving up 20 points per game, which is 42nd in the country. They are giving up 147.8 passing yards and 217.8 rushing yards per game.

South Florida vs. North Texas Picks

Point Spread Pick for South Florida vs. North Texas

  • South Florida Bulls (Pickem) (4 Units)

Both teams are rolling, but South Florida has the edge here because they have a balanced attack, and they move the ball effectively through the air and on the ground. The Mean Green have been terrible against the run this season, and their pass defense has also given up some big plays, so expect them to keep the ball on the ground in this game.

Even though they’re also balanced offensively, the Bulls won't be as successful in this game because the Bulls have a very good run defense, which will allow them to limit the damage the Mean Green inflict on the ground. If they are unable to run the ball, the Mean Green will throw the ball more than they usually do, which will play to South Florida’s strength. Go with USF to cover the spread.

Over/Under Pick for South Florida vs. North Texas

  • Under 66.5 (4 Units)

The Bulls average 44.2 points per game. They run the ball 50 percent of the time with the 38th-best ground game in the country, and they’re facing a team that is 125th against the run and is giving up 20 points per game. The Mean Green average 44.8 points per game. They run the ball 50 percent of the time with the 28th-best ground game in the country, and they’re playing a team that is 61st against the run and is giving up 22.4 points per game. Don’t expect these teams to score enough points to push the score over the total.

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