Southern Mississippi vs. South Alabama, Picks and Prediction, Saturday, November 22, 2025
Use Code WWWC Southern Mississippi (7-3, 5-1 Sun Belt) will be going for their fourth consecutive road win when they visit Hancock Whitney Stadium on Saturday afternoon to face South Alabama (3-7, 2-4 Sun Belt) at 3:30 PM. ET. Read on to find out which team picks up the win in this Golden Eagles vs. Jaguars prediction. Do you need a boost in your handicapping? Try our NCAAF FREE Picks.
The Golden Eagles are coming off a 41-14 loss to Texas State as three-point favorites. The Jaguars are coming off a 26-14 win over Louisiana Monroe as four-point favorites.
South Alabama is 5-0 in five games against Southern Mississippi. The Jaguars won last season’s meeting, 35-14.
Southern Mississippi Trying To Bounce Back From Loss
The Golden Eagles had their five-game winning streak snapped by Texas State in their last game. They will try to bounce back from the loss and pick up their sixth win in their last seven games when they play on Saturday.
Get Free $30 Credit for Premium Picks + Exclusive Discounts
Subscribe Now
Southern Mississippi averages 30.5 points per game, which is 50th in the nation. They throw for 259.2 yards and rush for 150.8 yards per game.
Braylon Braxton has completed 67 percent of his passes for 2,187 yards, 19 touchdowns, and five interceptions. With Braxton injured last week against Texas State, Landry Lyddy struggled with two interceptions, though he did throw for 267 yards (29 of 44). The UAB transfer has 406 yards passing with two TDs and three picks this season. Jefferey Pittman has 124 carries for 548 yards and seven touchdowns, while Elijah Metcalf has 40 catches for 541 yards and two touchdowns.
Southern Mississippi is giving up 25.9 points per game, which is 79th in the nation. They’re giving up 233.4 passing yards and 169.8 rushing yards per game.
Key Injuries for Southern Miss:
QB-Braylon Braxton (knee) and TE-Kadinn Morris (Undisclosed) are questionable for this game.
South Alabama Going For Second Consecutive Win
The Jaguars bounced back from their loss to Louisiana with a win over Louisiana-Monroe in their last game. They will try to keep the momentum going and pick up their second straight win when they play on Saturday.
South Alabama averages 25 points per game, which is 83rd in the country. They throw for 183.1 yards and rush for 192.8 yards per game.
Bishop Davenport has completed 67 percent of his passes for 1,826 yards, 12 touchdowns, and five interceptions. He also has 281 rushing yards and seven touchdowns. Kentrel Bullock leads the team with 180 carries for 814 yards and 10 touchdowns, while Devin Voisin has 53 catches for 688 yards and four touchdowns.
South Alabama is giving up 28.1 points per game, which is 93rd in the nation. They’re giving up 180 passing yards and 180 rushing yards per game.
Key Injuries for South Alabama:
RB-PJ Martin (Undisclosed) and WR-Nick Simmons (Undisclosed) have been ruled out of this game. WR-Brendan Jenkins (Undisclosed) and TE-Maddox Lynch (Undisclosed) are questionable for this game.
Southern Mississippi vs. South Alabama Picks
Point Spread Pick and Prediction for Southern Miss vs. South Alabama
- Southern Miss -1.5
The Golden Eagles have won five of their last six games, while the Jaguars have lost four of their last six games. Braxton could go in this game and even if he doesn't, Lyddy is certainly capable of playing better than he idd last week as he has some experience at UAB and Louisiana Tech. Southern Mississippi has the edge here because they’re playing well offensively, scoring more than 30 points per game. They have a balanced attack with one of the best passing games in the country, and they’re facing a team that is one of the worst in the country against the pass and is even worse against the run, so expect the Golden Eagles to have their way offensively.
The Jaguars will have a hard time keeping up with the Golden Eagles because they’re not as good offensively. They have one of the worst passing games in the nation, but their ground game is very potent. The Golden Eagles don’t have to worry about the Jaguars beating them through the air, which will allow them to stack the box and limit the damage the Jaguars do on the ground. Go with Southern Mississippi to cover the spread.
Over/Under Pick for Southern Miss vs. USA
- Over 53.5 (4 Units)
The Jaguars played over the total in two of their last three games, while the Golden Eagles played over the total in three of their last six games. South Alabama averages 25 points per game. They run the ball 61 percent of the time with the 20th-ranked ground game in the country, and they’re facing a team that is 93rd against the run and is giving up 25.9 points per game. The Golden Eagles average 30.5 points per game. They run the ball 55 percent of the time with the 62nd-ranked ground game in the country, and they’re facing a team that is giving up 28.1 points per game. Expect these teams to score enough points to push the score over the total. The Golden Eagles and Jaguars played over the total in two of their last three meetings.
Betting on College Football?
- Bet with other College Football fans at the best sportsbooks
- Sign up today and get started with the latest college football sportsbook promos
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days
