Tulane vs South Alabama Picks and Prediction, Saturday, September 6, 2025
Tulane (1-0, 0-0 American) will be going for their second consecutive win when they visit Hancock Whitney Stadium on Saturday night to face South Alabama (1-0, 0-0 Sun Belt) at 7 PM. ET. Read on to find out which team picks up the win in this Green Wave vs. Jaguars prediction and get more quality College Football Picks.
The Green Wave are coming off a 23-3 win over Northwestern as 5.5-point favorites. The Jaguars are coming off a 38-21 win over Morgan State as 28.5-point favorites.
Tulane is 2-1 in three games against South Alabama. They won the last meeting in 2023, 37-17.
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Tulane Going For First Road Win
The Green Wave are off to a good start, with a win over Northwestern. They are hitting the road for the first time and will be hoping for a similar result when they face the Jaguars on Saturday.
Tulane scored 23 points in their first game. They threw for 152 yards and rushed for 269 yards in the win.
Jake Retzlaff, who transferred from BYU in the offseason, completed 58 percent of his passes for 152 yards and one touchdown in his debut. He also had 10 carries for 113 yards and one touchdown. Maurice Turner had 14 carries for 86 yards, while Omari Hayes had nine catches for 74 yards.
Tulane gave up three points in their first game. They gave up 161 passing yards and 76 rushing yards in the win.
South Alabama Going For Second Consecutive Win
The Jaguars kicked off their season with a convincing win over a Morgan State team they were expected to blow out. They will face a tougher test this week and will try to pick up their second win in a row when they play on Saturday.
South Alabama scored 38 points in their first game. They threw for 174 yards and rushed for 193 yards in the win.
Bishop Davenport completed 86 percent of his passes for 166 yards and two touchdowns in the win over the Bears. Kentrel Bullock led the team with 23 carries for 127 yards and two touchdowns, while Devin Voisin led the team with seven catches for 69 yards and one touchdown.
South Alabama gave up 21 points in their first game. They gave up 159 passing yards and 181 rushing yards.
Tulane vs. South Alabama Pick
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Rob Vinciletti | +1,570.00 |
| 2 |  Dan Kaiser | +1,223.00 |
| 3 |  Ross Benjamin | +1,000.00 |
| 4 |  Earle Sports Bets | +916.00 |
| 5 |  David Hess | +706.00 |
Spread Pick for Tulane vs. USA
- Tulane Green Wave -10.5 (4 Units)
The Green Wave looked good offensively in their first game, especially on the ground, where they racked up close to 270 yards. The Jaguars were unable to stop the run in their first game, giving up more than 180 yards on the ground, and they’re facing a much better team in terms of talent, so expect them to have a hard time slowing down the Green Wave.
South Alabama will also struggle offensively in this game because it won’t be able to throw the ball against the Green Wave, who held Northwestern under 200 passing yards and had four interceptions. Their inability to throw the ball will allow the Green Wave to stack the box and slow down their ground game, so expect them to have a hard time keeping up with the Green Wave. Take Tulane to cover the spread.
Over/Under Pick for Tulane vs. South Florida
- Under 51.5 (4 Units)
The Green Wave played under the total in three of their last four games, while the Jaguars played under the total in three of their last five games. Tulane scored 23 points in their first game. They dominated on the ground, racking up more than 260 yards, and they’re facing a team that gave up over 180 rushing yards in their first game while giving up 21 points. The Jaguars scored 38 points in their first game. They also dominated on the ground, racking up more than 190 rushing yards. They are facing a team that gave up less than 100 rushing yards in their first game and gave up three total points. Don’t expect these teams to score enough points to push the score over the total.
The Tulane Green Wave will be going for their third consecutive win over the South Alabama Jaguars when they play on Saturday night. Which one of these teams will get the win? Continue reading this Green Wave vs. Jaguars prediction to find out.
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