UCLA Bruins vs. Ohio State Buckeyes Picks and Prediction for Saturday, November 15, 2025
It’s a matchup on the gridiron between Big Ten foes as they tangle in the Buckeye State, looking to earn a win. The UCLA Bruins are on the road as they travel to take on the #1 Ohio State Buckeyes Saturday night. UCLA comes in off a 28-21 home defeat to Nebraska last Saturday in their previous contest, failing to cover the line as a two-point underdog. Ohio State rolled to a 34-10 blowout win over Purdue on the road, failing to cover the line as a 28.5-point favorite, in their previous contest last Saturday. In the all-time series between the programs, the ledger stands at 4-4-1, with UCLA taking a 13-6 home win in the most recent meeting on September 22, 2001. Read more about this UCLA vs. Ohio State prediction! Don’t get penalized! Increase your bankroll with our NCAAF Betting Picks!
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UCLA Try to Earn Massive Upset Win
UCLA suffered their second straight loss as they were beaten by Nebraska at home last week. The Bruins dropped to 3-6 overall and stand 3-3 in the Big Ten entering this contest as they try to earn a massive upset win on the road. Against Nebraska, UCLA trailed 7-0 after the opening quarter and surrendered 21 unanswered points after tying the game at seven to trail 28-7 early in the third quarter. The Bruins clawed to within seven with just under five minutes to play but never got the ball back again. UCLA was edged 361-348 in total offense and picked up 21 first downs while allowing 20 in the contest. Each team finished with an even 30 minutes in time of possession with neither side committing a turnover in the contest.
The Bruins enter this game 111th in the FBS in passing offense with an average of 184.3 yards per game through the air. UCLA is 62nd in the country in rushing offense by averaging 160.2 yards per contest on the ground. The Bruins average 20.4 points per game, which is 117th in the FBS in scoring offense. Meanwhile, UCLA’s defense ranks 112th in scoring defense as they allow an average of 30.7 points per contest. Nico Iamaleava is 165 of 259 passing for 1,659 yards with 12 touchdowns and seven interceptions this season while leading the team with 474 yards plus four scores on the ground. Jaivian Thomas leads the Bruins’ running backs on the ground with 72 carries for 277 yards and a score on the year. Jalen Berger (64 carries, 268 yards, two TD) and Anthony Woods (48 carries, 232 yards) are more than capable of doing damage when they touch the ball. Kwazi Gilmer leads the team with 33 receptions for 395 yards and two scores. Mikey Matthews (19 catches, 254 yards, TD), Titus Mokiao-Atimalala (19 grabs, 247 yards, three TD), Rico Flores Jr. (23 catches, 212 yards) and Woods (17 receptions, 166 yards, two TD) are other targets for Iamaleava in the aerial assault. Mateen Bhaghani has hit all 17 extra point attempts and 14 of 18 field goal attempts with a long of 54 this season.
Buckeyes Seeking to Remain Unbeaten
Ohio State cruised past Purdue on the road in their previous contest to maintain the #1 ranking in the CFP rankings. The Buckeyes enter this game 10-0 on the season and 6-0 in the Big Ten, leaving them half a game behind Indiana for the top spot in the conference. Against Purdue, Ohio State trailed 3-0 after the opening quarter before outscoring the Boilermakers 24-0 in the second quarter for a 24-3 halftime advantage and cruised the rest of the way. The Buckeyes owned a 473-186 advantage in total offense, rolled up a 30-13 edge in first downs and dominated time of possession by a 40:53 to 19:07 margin in the game. Both teams committed one turnover in the contest.
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Earle Sports Bets | +1,154.00 |
| 2 |  David Hess | +868.00 |
| 3 |  Stephen Nover | +634.00 |
| 4 |  Rob Vincilleti | +600.00 |
| 5 |  Dan Kaiser | +547.00 |
On the season, the Buckeyes are 19th in the nation in passing offense with 286.3 yards per game through the air while the team is 68th in the country in rushing by averaging 155.3 yards per contest. Ohio State is 18th in the FBS in scoring offense with 36.3 points per game, while they rank 1st in the nation in scoring defense as they allow 7.2 points per contest. Julian Sayin is 203 of 251 passing for 2,491 yards with 24 touchdowns and four interceptions; he’s added 21 yards on the ground. Lincoln Kienholz (seven of eight, 86 yards, TD, 26 rush yards, two TD) and Tavien St. Clair (zero of two, zero yards) have seen limited action. Bo Jackson (95 carries, 613 yards, two TD), CJ Donaldson (72 carries, 278 yards, nine TD) and James Peoples (52 carries, 247 yards) have shared the run game duties on the year. When the Buckeyes go back to pass, Jeremiah Smith leads the team with 65 receptions for 862 yards and 10 scores this season. Carnell Tate (39 receptions, 711 yards, seven TD), tight end Max Klare (26 catches, 269 yards, TD), Jackson (12 grabs, 124 yards, TD) and Brandon Inniss (21 catches, 180 yards, TD) are each over the 100-yard mark in receiving yards this season. Jayden Fielding is 38 of 38 on extra points and 11 of 14 on field goal attempts with a long of 49 this season. Jackson Courville has hit all four extra point attempts and has not attempted a field goal this year.
Tate (undisclosed) is questionable for this contest.
UCLA vs. Ohio State Prediction
| # | Handicapper | Profit |
|---|---|---|
| 1 | Rob Vincilleti | +1,778.00 |
| 2 |  Ross Benjamin | +1,716.00 |
| 3 | David Hess | +1,326.00 |
| 4 | Earle Sports Bets | +1,323.00 |
| 5 | Dan Kaiser | +1,071.00 |
Spread Pick for UCLA vs. Ohio State
- Ohio State -31.5 (4 units)
UCLA had a three-game win streak but enters this game off two straight losses. Iamaleva faced Ohio State’s defense in the CFP last season, going 14 of 31 for 104 yards while adding 47 yards and two scores on the ground in Tennessee’s 42-17 loss. He now has to deal with a Buckeyes defense that gives up just 128.7 yards per game through the air and 82.9 yards per contest (2.8 yards per carry) on the ground this season, with lesser weapons than he had a season ago. UCLA gave up almost as many points in their loss to Indiana (56) as Ohio State has given up all season (65) in nine contests. Ohio State has allowed just one team to score more than 14 points against them this season. The Buckeyes win this one in a romp.
Over/Under Pick for UCLA vs. Ohio State
- Over 47.5 (4 units)
UCLA has seen the under post a 5-4 mark on the year, though they come in off back-to-back overs entering this contest. The Bruins are struggling to keep opposing teams from scoring, as they have allowed at least 30 points five times this season. Ohio State has stayed under the number in six of their nine games on the season as their defense has been lights out all year long. The Buckeyes are a good offensive team and should be able to pile up points. Ohio State has put up at least 34 points in seven of their nine games on the year. Expect at least a 40-burger for the Buckeyes here as they push this over the total.
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