UTSA vs. Charlotte, Picks and Prediction, Saturday, November 15, 2025
Use Code WWWC UTSA (4-5, 2-3 American) will be trying to snap their three-game road losing streak when they visit Jerry Richardson Stadium on Saturday afternoon to face Charlotte (1-8, 0-6 American) at 12 PM. ET. Read on to find out which team picks up the win in this Roadrunners vs. 49ers prediction. Don’t get sacked this football season! Try our College Football Picks!
The Roadrunners are coming off a 55-23 loss to USF as 14-point underdogs. The 49ers are coming off a 48-22 loss to East Carolina as 28-point underdogs.
UTSA is 2-0 in two games against Charlotte. The last meeting between the two teams was in 2016.
UTSA Trying To Bounce Back From Loss
The Roadrunners followed up their win over Tulane with a loss to USF in their last game. They will try to bounce back from the loss and put an end to their road losing streak with a win on Saturday.
Get Free $30 Credit for Premium Picks + Exclusive Discounts
Subscribe Now
UTSA averages 32.8 points per game, which is 37th in the nation. They throw for 233.3 yards and rush for 166.4 yards per game.
Owen McCown has completed 68 percent of his passes for 1,880 yards, 18 touchdowns, and five interceptions. Robert Henry Jr. leads the team with 130 carries for 982 yards and nine touchdowns, while Devin McCuin leads the team with 45 catches for 467 yards and six touchdowns.
UTSA is giving up 33 points per game, which is 123rd in the nation. They’re giving up 242.1 passing yards and 175 rushing yards per game.
Injuries: WR-Willie McCoy (Undisclosed) is questionable for this game.
Charlotte Trying To Snap Seven-Game Losing Streak
The 49ers haven’t had much go their way this season, with only one win in nine games. They have lost seven straight games and will try to put an end to the streak and pick up their first conference win of the season when they play on Saturday.
Charlotte averages 18 points per game, which is 127th in the nation. They throw for 225.4 yards and rush for 99.3 yards per game.
Grayson Loftis has completed 53 percent of his passes for 1,045 yards, eight touchdowns, and five interceptions. Rod Gainey Jr. leads the team with 56 carries for 215 yards and one touchdown, while Javen Nicholas leads the team with 44 catches for 631 yards and five touchdowns.
Charlotte is giving up 38.4 points per game, which is 134th in the nation. They’re giving up 246.9 passing yards and 224.9 rushing yards per game.
Injuries: TE-Joey Bearnes III (undisclosed) and RB-CJ Stokes (Undisclosed) are questionable for this game.
UTSA vs. Charlotte Picks
Point Spread Pick for UTSA vs. Charlotte
- UTSA Roadrunners -18.5 (4 Units)
The Roadrunners have won four of their last seven games, while the 49ers have lost seven of their last eight games. UTSA has the edge here because they have one of the best offenses in the country and can beat opponents through the air and on the ground. The 49ers are terrible defensively, and they’ve been unable to slow down the run or pass, so expect them to have a hard time slowing down the Roadrunners.
Charlotte will have a hard time keeping up in this game because they have one of the worst offenses in the country. They have one of the worst ground games in the country, and a passing game that’s a little bit better. The Roadrunners don’t have to worry about the 49ers beating them on the ground, which will allow them to keep pressure on Loftis and force him to make costly mistakes. Go with UTSA to cover the spread.
Over/Under Pick for UTSA vs. Charlotte
- Over 59.5 (4 Units)
The Roadrunners played over the total in their last four games, while the 49ers played over the total in their last three games. UTSA averages 32.8 points per game. They throw the ball 52 percent of the time with the 60th-ranked passing attack in the nation, and they’re facing a team that is 102nd against the pass and is giving up 38.4 points per game. The 49ers average 18 points per game. They throw the ball 53 percent of the time with the 91st-ranked passing attack in the country, and they’re facing a team that is 92nd against the pass and is giving up 33 points per game. Expect these teams to score enough points to push the score over the total.
Betting on College Football?
- Bet with other College Football fans at the best sportsbooks
- Sign up today and get started with the latest college football sportsbook promos
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days
