West Virginia vs Ohio Picks and Prediction, Saturday, September 6, 2025
West Virginia (1-0, 0-0 Big 12) will be trying to pick up their first road win of the season when they visit Peden Stadium on Saturday afternoon to face Ohio (0-1, 0-0 MAC) on Saturday afternoon. Read on to find out which team picks up the win in this Mountaineers vs. Bobcats prediction and get more College Football Picks!
The Mountaineers are coming off a 45-3 win over Robert Morris as 40-point favorites. The Bobcats are coming off a 34-31 loss to Rutgers as 15.5-point underdogs.
West Virginia won the lone meeting between the two teams in 2001.
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West Virginia Going For Second Consecutive Win
The Mountaineers kicked off the second Rich Rodriguez era with a blowout win over Robert Morris at home. They are hitting the road for the first time and will be hoping for a similar result against the Bobcats.
West Virginia scored 45 points in their first game. They threw for 232 yards and rushed for 393 yards in the win.
Nicco Marchiol completed 85 percent of his passes for 224 yards and one touchdown in the win over the Colonials. He also had 13 carries for 56 yards and one touchdown. Jaheim White led the team with 18 carries for 93 yards and two touchdowns, while Cam Vaugh had seven catches for 127 yards and one touchdown.
West Virginia gave up three points in their first game. They gave up 70 passing yards and 53 rushing yards.
Ohio Trying To Bounce Back From Loss
The Bobcats put up a good fight against the heavily favored Scarlet Knights in their first game, but they ultimately fell short, picking up their first loss off the season. They will try to bounce back from the loss and pick up their first win of the season when they play the Mountaineers.
Ohio scored 31 points in their first game. They threw for 239 yards and rushed for 201 yards in the loss.
Parker Navarro completed 68 percent of his passes for 239 yards and three touchdowns in the loss to Rutgers. He also had nine carries for 93 yards and one touchdown. Sieh Bangura had 16 carries for 93 yards and one touchdown, while Chase Hendricks had nine catches for 115 yards.
Ohio gave up 34 points in their first game. They gave up 252 passing yards and 147 rushing yards in the loss.
West Virginia vs. Ohio Pick
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Earle Sports Bets | +2,298.00 |
| 2 |  Ross Benjamin | +1,840.00 |
| 3 |  Rob Vincilleti | +1,757.00 |
| 4 |  David Hess | +1,745.00 |
| 5 |  Dan Kaiser | +987.00 |
Spread Pick for West Virginia vs. Ohio
- West Virginia Mountaineers -3.5 (4 Units)
The Mountaineers had their way offensively in their last game, especially on the ground where they racked up close to 400 yards and five touchdowns. The Bobcats didn’t play well defensively in their first game, especially against the pass. With the Mountaineers capable of beating them through the air and on the ground, expect the Bobcats to have their hands full defensively in this game.
Even though the Bobcats looked good offensively in their first game, expect them to struggle in this game because they won’t be able to run the ball effectively against the Mountaineers, who held the Colonials to 1.4 yards per carry even though they ran the ball 37 times. They also won’t be able to throw the ball effectively against a secondary that gave up less than 100 passing yards in their first game, so expect the Mountaineers to dominate this game. Go with West Virginia to cover the spread.
Over/Under Pick for West Virginia vs. Ohio
- Under 60.5 (4 Units)
The Bobcats played under the total in two of their last three games, while the Mountaineers played under the total in two of their last four games. Ohio scored 31 points in their first game. They moved the ball well on the ground, rushing for over 200 yards. They are facing a team that gave up less than 100 rushing yards in their first game and gave up three total points. The Mountaineers scored 45 points in their first game, which was on their home field. They rushed for over 350 yards in that game and they’re facing a team that played well against the run in their first game and gave up 34 points. Don’t expect these teams to score enough points to push the score over the total.
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