Wisconsin vs. Indiana Picks and Prediction for Saturday, November 15, 2025
On Saturday, the Wisconsin Badgers will play the Indiana Hoosiers in a Week 12 NCAAF game at Memorial Stadium. The Big Ten Conference matchup is scheduled for noon ET.
The Hoosiers are 29-point spread favorites, and the total is 44 points scored.
This Wisconsin vs. Indiana prediction highlights a Badgers squad that snapped a six-game losing streak last week and a Hoosiers team that escaped Happy Valley with a comeback victory over Penn State. Saturday's game marks the 64th all-time college football game between IU and UW. Wisconsin leads the series 41-20-2, but Indiana has won the last two matchups.
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Badgers finally got back in the win column last week
Wisconsin (3-6 SU, 4-5 ATS, and 2-6-1 O/U) defeated Washington 13-10 last Saturday. The Badgers escaped the basement of the Big Ten football standings with the victory, boosting their conference record to 1-5.
UW upset the 23rd-ranked Huskies with a dominant defensive performance. While the home team was outgained 251-205, passing for just 48 yards, they forced two Huskies turnovers and had nine tackles for loss. The Badgers also had to overcome a first-quarter injury to QB Danny O'Neil, who was carted off with a leg injury. It was their first win since September 6 and first over a Power-4 team in their last 12 tries.
“It just feels incredible," Wisconsin offensive tackle Riley Mahlman said. “You kind of have these thoughts in the back of your mind. I didn't know if I was ever going to win another game as a Wisconsin Badger. That was just the reality.”
The Badgers haven't named a starting QB for Saturday's game. True freshman Carter Smith and senior Hunter Simmons (Southern Illinois transfer) are the only healthy scholarship signal-callers on the roster. While both saw the field against Washington, neither was efficient, as Smith passed for eight yards and Simmons passed for 16. The Badgers' top receiving target is senior WR Vinny Anthony II (26 receptions for 291 yards and one TD), and with leading rusher Dilin Jones out (76 carries for 300 yards and two TDs), freshman RB Gideon Ituka (51 carries for 223 yards) leads the Wisconsin run game.
Wisconsin scores 12.6 points per game (134th) and averages 255.6 total yards (135th), including 140.6 passing yards (131st) and 115.0 rushing yards (117th). The UW defense allows 22.3 points (50th) and 331.0 total yards (40th) per game, including 219.6 passing yards (68th) and 111.4 rushing yards (26th).
Wisconsin Badgers Football Injury Report: LB Christian Alliegro, QB Danny O'Neil, QB Billy Edwards Jr., RB Cade Yacamelli, and S Preston Zachman are among the notable players questionable to play against Indiana.
Indiana just keeps winning
Indiana (10-0 SU, 6-4 ATS, and 6-3-1 O/U) beat Penn State 27-24 last weekend, keeping its undefeated season alive. The Hoosiers are the only B1G team with a 7-0 conference record this season.
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Earle Sports Bets | +1,154.00 |
| 2 |  David Hess | +808.00 |
| 3 |  Stephen Nover | +644.00 |
| 4 |  Dan Kaiser | +547.00 |
| 5 |  Rob Vincilleti | +500.00 |
It wasn't easy, but IU finished the job in its closest win of the season against Penn State. Despite a 20-7 third-quarter lead, Indiana barely escaped University Park with a win, needing an 87-yard touchdown drive with less than two minutes remaining to hold off the Nittany Lions. QB Fernando Mendoza connected with WR Omar Cooper Jr. for a toe-tapping, back-of-the-endzone touchdown with just 36 seconds left, a highlight Indiana fans will never forget.
“It was the most improbable victory I have ever been a part of,” Hoosiers head coach Curt Cignetti said. “And there couldn’t have been a better place to make it happen.”
The Cal transfer Mendoza leads the Hoosiers' offense with 2,342 passing yards and a 26:5 TD:INT ratio. He has completed 71.3 percent of his passes, averaging 9.2 yards per attempt. Mendoza's top receiving targets are junior WR Omar Cooper Jr. (52 receptions for 701 yards and nine TDs) and senior WR Elijah Sarratt (45 receptions for 609 yards and ten TDs). Senior RBs Roman Hemby (137 carries for 656 yards and five TDs) and Kaelon Black (108 carries for 651 yards and five scores) pace the IU run game.
Indiana scores 44.5 points per game (1st) and averages 487.0 total yards (6th), including 255.1 passing yards (42nd) and 231.9 rushing yards (9th). The Hoosiers' defense surrenders 12.1 points (2nd) and 257.1 total yards (5th) per game, including 173.4 passing yards (17th) and 83.7 rushing yards (6th).
Indiana Hoosiers Football Injury Report: WR Elijah Sarratt is questionable to play against Wisconsin.
Wisconsin vs. Indiana Pick and Preview
| # | Handicapper | Profit |
|---|---|---|
| 1 | Earle Sports Bets | +2,298.00 |
| 2 |  Ross Benjamin | +1,840.00 |
| 3 | Rob Vincilleti | +1,757.00 |
| 4 | David Hess | +1,745.00 |
| 5 | Dan Kaiser | +987.00 |
Spread Pick for Wisconsin vs. Indiana
- Hoosiers -29 (5 Units)
Betting Trend: Indiana is 3-1 ATS as four-score favorites this season and 6-2 ATS vs. conference opponents at home under Cignetti. One of those losses was a "bad beat" earlier this season, when Michigan State hit a field goal with 33 seconds left to cover the 26-point spread by one point.
Indiana will show resolve after its near-loss to Penn State, shutting the door quickly on Wisconsin. The Hoosiers have overwhelmed most opponents by jumping on them early and piling on points even after the game is already decided. I wouldn't expect that to change in their final home game of a historic regular season. While the Badgers do field a competitive defense, their offense lacks a pulse. When O'Neil exited last week's game, UW looked like a bad high school football team, as neither of the QBs that came in could complete a pass.
The Hooisers will stomp on an offensive-challenged, injury-riddled, and directionless Badgers team on Saturday, getting their mojo back.
Over/Under Pick for Wisconsin vs. Indiana
- Under 44 (5 Units)
Betting Trend: The under is 5-0-1 in Wisconsin's Big Ten games this season. The only game that didn't go under was a 37-point total push, when Iowa beat Wisconsin 37-0.
Will the Badgers score more than six points on Saturday? I don't think so. The Hoosiers have been among the best defensive teams in the country this season (5th in total defense), and the Badgers' offense ranks in the bottom 20. With several QB and RB injuries, the visitors will struggle to move the chains (129th in third-down conversion rate) against the home team (5th in opponent third-down conversion rate). Indiana will score a few early touchdowns and cruise to a win in the second half, covering the spread without pushing the total over 44 points.
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