Arizona Diamondbacks vs. Cincinnati Reds, Picks and Prediction, Friday, June 12, 2026

By: Bosun Akinpelu Published 06/12/2026, 05:10 AM ET
Diamondbacks vs. Reds prediction
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Arizona (34-33) will be trying to take the series lead when they visit Great American Ball Park on Friday night to face Cincinnati (32-35) in the first game of their three-game series at 7:10 PM. ET. Read on to find out which team picks up the win in this Diamondbacks vs. Reds prediction. When it comes to MLB picks, our MLB Predictions are stellar.

Eduardo Rodriguez, 5-2, 2.52 ERA, will get the start for the Diamondbacks. The Reds will counter with Nick Lodolo, 2-1, 5.51 ERA.

Arizona and Cincinnati split their last 10 meetings.

**This preview was written before Thursday’s game was played.**

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Diamondbacks Trying To Snap Two-Series Losing Streak

The Diamondbacks followed up their series split with the Dodgers with series losses to the Nationals and Marlins. They will try to put an end to the losing streak and make up some ground in the NL West when they play on Friday.

Arizona averages 4.31 runs per game, which is 18th in the league. Their .240 batting average is 18th in the league. Their .307 on base percentage is 27th, while their .389 slugging percentage is 17th.

Corbin Carroll leads the Diamondbacks with a .284 batting average, while Ketel Marte leads the team with 11 home runs and 40 RBI.

Arizona is giving up 4.64 runs per game, which is 20th in the league. Opponents have a .248 batting average against the Diamondbacks, which is 20th in the league. Their 4.30 ERA is 19th, while their 1.28 WHIP is 14th.

In his last start, Rodriguez gave up six hits and four runs in 6.1 innings, leading to a 6-1 loss to Washington. He is 1-1 with a 2.45 ERA in two games against the Reds.

Reds Looking For First Series Win In June

The Reds haven’t had much go their way this month, losing all four series they have played. They’re facing a team that also struggled in recent weeks and will try to put an end to their streak this weekend.

Cincinnati averages 4.27 runs per game, which is 19th in the league. Their .231 batting average is 26th in the league. Their .313 on base percentage is 23rd, while their .395 slugging percentage is 12th.

Elly De La Cruz leads the Reds with a .280 batting average, while Sal Stewart leads the team with 13 home runs and 42 RBI.

Cincinnati is giving up 5.07 runs per game, which is 27th in the league. Opponents have a .252 batting average against the Reds, which is 24th in the league. Their 4.79 ERA is 28th, while their 1.47 WHIP is 29th.

In his last start, Lodolo gave up 10 hits and four runs in five innings, leading to a 6-5 loss to St. Louis. He is 0-0 with a 4.50 ERA in one game against the Diamondbacks.

Diamondbacks vs. Reds Picks

Money Line Pick for Diamondbacks vs. Reds

  • Arizona Diamondbacks ML (4 Units)

The Diamondbacks have the edge here because they’ve done a better job offensively and scored 11 runs in their last three games. They’ve had a lot of success against left-handers, and they’re going up against Lodolo, who struggled on the mound in recent starts, especially at home, where he gave up 12 runs in his last three starts. With Cincinnati’s bullpen also struggling, they will have a hard time slowing down the Diamondbacks.

The Reds will have a hard time keeping up offensively because they struggled in recent home games, scoring eight runs in their last three home games. They haven’t been very good against left-handers, and they’re going up against Rodriguez, who gave up seven runs in his last four starts. He gave up seven runs in his last three road starts, so expect him to keep Cincinnati’s offense in check. Take Arizona on the money line.

Over/Under Pick for Diamondbacks vs. Reds

  • Under (4 Units)

The Diamondbacks average 4.31 runs per game. They’re batting .273 against left-handers, and they’re facing a starter who gave up eight runs in his last three starts. The Reds average 4.27 runs per game. They’re batting .230 against left-handers, and they’re facing a starter who gave up seven runs in his last three starts. Don’t expect these teams to score enough runs to push the score over the total.

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