Arizona Diamondbacks vs Los Angeles Dodgers Picks and Prediction for Saturday, March 28, 2026

By: David Anicetti Published 03/28/2026, 04:30 AM ET
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The Arizona Diamondbacks (0-1) visit the Los Angeles Dodgers (1-0) at Dodger Stadium on Saturday at 9:10 PM ET on MLB.TV. Los Angeles opened the series with an 8-2 win on Thursday, using a five-run middle stretch to take control, while Arizona looks to respond after a quiet offensive performance outside of one inning. This preview was written before the completion of Fridayโ€™s game. The Dodgers enter as home favorites with the total sitting around 8.5. Build your bankroll with our free MLB picks.

Arizona Diamondbacks: Need More Consistent Offense

Arizona opened the season with a loss despite showing flashes of production early. The Diamondbacks scored twice in the fourth inning but were held scoreless the rest of the game, finishing with just six hits and limited opportunities. That inconsistency reflects a lineup that can produce in short bursts but has struggled to sustain offense across full games.

Geraldo Perdomo stood out in the opener, going 2-for-4 with a home run and two RBIs. Corbin Carroll added a hit at the top of the order, while Ketel Marte and Nolan Arenado remain key contributors expected to drive production moving forward. However, the middle of the lineup did not generate enough pressure, and Arizona finished just 1-for-3 with runners in scoring position.

The Diamondbacks are built around contact and situational hitting rather than relying on power. When the lineup is working, Arizona can string together hits and create scoring chances. In the opener, that approach stalled after the fourth inning, and the team struggled to generate baserunners consistently against a strong pitching staff.

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The Diamondbacks also enter with several injuries affecting depth. Merrill Kelly is on the 15-day IL, while Lourdes Gurriel Jr. remains out. Pavin Smith is day-to-day, and Adrian Del Castillo is unavailable.

Los Angeles Dodgers: Depth Showing Early

Los Angeles opened the season with a strong offensive performance, scoring eight runs on 10 hits while showing depth throughout the lineup. The Dodgers produced across multiple innings, including a four-run fifth and four-run seventh, highlighting their ability to take control quickly.

Will Smith led the way with a home run and three RBIs, while Andy Pages added a three-run shot that shifted momentum. Shohei Ohtani reached base and scored, while Mookie Betts and Freddie Freeman contributed in the six-run win. This lineup has multiple players capable of producing in key spots, making it difficult for opposing pitchers.

The Dodgersโ€™ offense is built on patience and power. Los Angeles worked counts effectively in the opener and capitalized on mistakes, particularly with two-strike hitting during the fifth inning rally. That ability to extend innings and generate runs without relying on one player makes the lineup difficult to contain.

The Dodgers also have some injuries to monitor. Brusdar Graterol and Brock Stewart are on the 15-day IL, while Gavin Stone and Landon Knack are also unavailable. Enrique Hernandez remains out long-term.

Pitching Matchup

Arizona Diamondbacks โ€“ Eduardo Rodriguez

Rodriguez went 9-9 with a 5.02 ERA and 1.54 WHIP last season. He can generate strikeouts but allows consistent contact, which can lead to extended innings against deeper lineups.

Los Angeles Dodgers โ€“ Tyler Glasnow

Glasnow finished with a 3.19 ERA and 1.10 WHIP while maintaining strong strikeout numbers. He limits baserunners and can control the pace of the game when working efficiently.

Arizona Diamondbacks vs Los Angeles Dodgers Pick

  • Los Angeles -1.5

Los Angeles holds the edge with a deeper lineup and a stronger pitching staff. The Dodgers showed in the opener that they can generate runs in multiple ways, while Arizona struggled to sustain offense beyond one inning. Glasnowโ€™s ability to limit baserunners adds another advantage. Over the course of the game, Los Angeles is more likely to control tempo and create consistent scoring opportunities.

Arizona Diamondbacks vs Los Angeles Dodgers - Over/Under Pick

  • Over 9.5

The total is at 9.5, and this matchup points toward potential scoring. Los Angeles has already shown it can generate offense at home, while Arizona should produce more than it did in the opener. At the same time, Glasnowโ€™s presence could limit Arizonaโ€™s output. With one lineup capable of carrying scoring and the other likely improving, the over is a reasonable play if Arizona contributes.

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