Arizona Diamondbacks vs St. Louis Cardinals Picks, Prediction, Odds, and Line Movement for Tuesday June 23 2026
Use Code WWWC Arizona visits St. Louis with updated picks, pitching analysis, and top MLB player props for Tuesday night.
Best Available Odds
Best Moneyline Odds: Arizona Diamondbacks (-104 at FanDuel) / St. Louis Cardinals (-112 at FanDuel)
Best Spread Odds: Arizona Diamondbacks -1.5 (+162 at FanDuel) / St. Louis Cardinals +1.5 (-196 at FanDuel)
Best Total Odds: Over 8.5 (-114 at FanDuel) / Under 8.5 (-106 at FanDuel)
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Game Info
Date: Tuesday, June 23, 2026
Time: 7:45 PM EDT
Location: Busch Stadium, St. Louis, MO
TV: DBACKS.TV, Cardinals.TV Presented by bet365
Arizona Diamondbacks vs St. Louis Cardinals Preview
The Arizona Diamondbacks enter Tuesday at 39-39 after dropping the series opener 3-2. Arizona has now lost three consecutive games and sits at .500 through its first 78 contests.
The Diamondbacks produced eight hits Monday but went 0-for-8 with runners in scoring position. They repeatedly created traffic against Andre Pallante and the St. Louis bullpen without delivering the hit required to complete a comeback.
Corbin Carroll and Ketel Marte each collected two hits. Carroll doubled and scored Arizona's first run, while Marte singled twice and stole his first base of the season.
Tommy Troy supplied the club's only home run with a 444-foot shot to centre field during the seventh inning. Nolan Arenado drove in Arizona's other run with a groundout during his first game back at Busch Stadium since being traded by the Cardinals.
Arizona has scored 333 runs while batting approximately .239 with a .309 on-base percentage and .384 slugging percentage. The Diamondbacks have received solid production near the top of the order but have not consistently converted baserunners into runs.
Carroll leads Arizona with a .284 average and .550 slugging percentage. He has 13 home runs, 42 RBIs, and remains the team's most dangerous combination of power and speed.
Marte has added 12 home runs and a team-high 46 RBIs. Gabriel Moreno has also been productive recently, going 13-for-37 with three doubles and two home runs over his last 10 games.
The Diamondbacks remain without Jordan Lawlar, who returned from a fractured wrist only to suffer a right hamstring strain. Lawlar had batted .316 through 12 games before returning to the injured list.
Arizona's rotation has also lost Michael Soroka for at least several weeks because of a glute strain. Soroka had gone 8-3 with a 3.07 ERA, making his absence significant for a pitching staff already operating without Corbin Burnes.
The injuries place additional pressure on Eduardo Rodriguez to provide length Tuesday. Arizona used four relievers during Monday's opener, although no bullpen arm threw more than one inning.
The St. Louis Cardinals enter at 42-34 and remain in second place in the NL Central. St. Louis improved to 22-17 at Busch Stadium with Monday's victory.
Alec Burleson, Blaze Jordan, and Nathan Church drove in the three Cardinals runs. Church singled, stole second, and later added an RBI single, while Jordan produced a sacrifice fly.
JJ Wetherholt continued his productive rookie season with two hits. He enters Tuesday 16-for-42 with three home runs and seven RBIs over his last 10 games.
St. Louis has scored 352 runs while batting approximately .249 with a .328 on-base percentage and .400 slugging percentage. The Cardinals have produced better season-long offensive numbers than Arizona in batting average, on-base percentage, slugging percentage, and home runs.
Jordan Walker leads St. Louis with 18 home runs and 58 RBIs. Burleson is batting .288 with a .355 on-base percentage and .492 slugging percentage, giving the Cardinals another reliable middle-order bat.
Iván Herrera has supplied additional power and patience. He enters batting .266 with 10 home runs and an .834 OPS, and he homered Sunday during St. Louis' victory over Kansas City.
The Cardinals are batting .288 over their last 10 games. Wetherholt, Burleson, Herrera, Walker, Masyn Winn, and Church have helped the offense remain productive even as the pitching staff has struggled.
St. Louis pitchers have recorded a 5.97 ERA over the last 10 games. The Cardinals have gone only 5-5 during that span despite the lineup's strong batting average.
The bullpen protected Monday's one-run lead after Ryne Stanek encountered trouble during the seventh inning. JoJo Romero, George Soriano, and Riley O'Brien combined to retire the final eight Arizona hitters.
O'Brien earned his 19th save after working a clean ninth inning. His usage Monday should not automatically make him unavailable, but St. Louis may prefer to avoid asking him for an extended appearance on consecutive nights.
Starting Pitchers and Pitching Matchup
The Diamondbacks will start left-hander Eduardo Rodriguez, who enters at 6-2 with a 2.45 ERA, 1.23 WHIP, and 65 strikeouts across 88.1 innings.
Rodriguez has allowed 74 hits, 35 walks, and nine home runs. His combination of contact management and timely pitching has allowed him to produce one of the lowest ERAs in the National League.
The veteran is coming off seven innings of one-run baseball against the Los Angeles Angels. Rodriguez allowed six hits, walked three, and recorded five strikeouts while throwing 100 pitches.
That performance followed a shortened start in Cincinnati. Rodriguez completed only 2.2 innings despite allowing one run because he issued five walks and required 85 pitches.
His previous appearance against Washington was less effective. Rodriguez allowed four earned runs on six hits across 6.1 innings but still recorded five strikeouts.
The three-start sequence illustrates the difference between Rodriguez's run prevention and command. He has allowed only six earned runs across 16 innings, but eight walks have created unnecessary traffic.
Rodriguez has completed at least six innings in three of his last four starts. Arizona should again give him an opportunity to work deep if he keeps his walk total under control.
His 2.45 ERA is considerably better than his fielding-independent pitching mark above four. Rodriguez has stranded a high percentage of baserunners and benefited from limiting damage after allowing hits or walks.
That difference does not mean immediate collapse is inevitable. Rodriguez has generated weak contact, avoided home runs, and repeatedly completed quality starts during the first half of the season.
The matchup against St. Louis is more difficult than the original article suggested. The Cardinals are batting .288 over their last 10 games and possess several right-handed hitters capable of attacking a left-handed starter.
Herrera, Walker, Wetherholt, Jordan, Winn, and Church can all receive favourable plate appearances against Rodriguez. St. Louis can also use Nelson Velázquez or Pedro Pagés if it wants additional right-handed power.
Burleson faces the left-on-left disadvantage, but his contact ability keeps him relevant. He extended his production Monday with an RBI infield single and has remained one of St. Louis' most consistent hitters.
The Cardinals have produced a .717 OPS against left-handed pitching. That is not an elite team split, but it is strong enough to prevent Rodriguez from being treated as an automatic shutdown starter.
St. Louis will counter with right-hander Kyle Leahy, who enters at 5-4 with a 4.63 ERA, 1.57 WHIP, and 59 strikeouts across 70 innings.
Leahy has allowed 84 hits and 26 walks. His high WHIP means opponents have averaged more than one and a half baserunners per inning, repeatedly forcing him to work from the stretch.
The right-hander is coming off six innings against San Diego. Leahy allowed three earned runs on seven hits and one walk while recording a season-high seven strikeouts.
He allowed four earned runs on eight hits across five innings during his previous appearance against Minnesota. Leahy recorded five strikeouts and walked one but could not consistently prevent hard contact.
Leahy has therefore surrendered 15 hits and seven earned runs across his last 11 innings. His strikeout production has improved, but opponents continue to create scoring opportunities through contact.
He owns a 4.33 ERA and 1.50 WHIP across his last seven starts. Those figures are better than his early-season results but still describe an average starter rather than a dominant one.
Leahy's workload has become more stable. He has completed at least five innings in six of his last seven starts and worked through the sixth inning against San Diego.
Arizona should have opportunities throughout the order. Carroll, Marte, Geraldo Perdomo, Arenado, Moreno, Lourdes Gurriel Jr., Troy, and Pavin Smith can all pressure a pitcher who allows frequent hits.
Carroll and Marte each produced two-hit games Monday. Their ability to reach base near the top of the order creates RBI opportunities for Arenado, Moreno, Gurriel, and the remaining middle-order hitters.
The Diamondbacks must improve with runners in scoring position. They outhit St. Louis during the opener and produced more extra-base hits but failed to convert eight opportunities.
Game Thesis: Arizona owns the clear starting-pitching advantage, but Rodriguez's ERA contains some regression risk and St. Louis is swinging the bat well. Leahy has allowed excessive traffic throughout the season and surrendered 15 hits across his last two starts, giving Arizona a path to four or five runs. Busch Stadium and two middling bullpens support another competitive game, but Rodriguez should provide enough early run prevention for the Diamondbacks to even the series.
⭐ Best Bet - Moneyline Pick: Arizona Diamondbacks (-104)
Arizona is the preferred moneyline side at a near-even price. The Diamondbacks receive the stronger starting pitcher without being required to lay a substantial favourite number on the road.
Rodriguez owns a 2.45 ERA and has allowed one earned run or fewer in three of his last four appearances. He enters after completing seven innings against the Angels and should again provide Arizona with length.
Leahy has been much easier to reach. His 1.57 WHIP is one of the weakest marks among regular starters, and he has allowed 84 hits across only 70 innings.
Arizona created consistent contact Monday against Pallante and the St. Louis bullpen. The Diamondbacks' failure was situational rather than a complete inability to reach base.
Carroll and Marte remain capable of setting the table, while Arenado, Moreno, Gurriel, Troy, and Smith give Arizona several opportunities to drive them home.
St. Louis' recent offensive form creates legitimate risk. Rodriguez must navigate a lineup batting .288 over the last 10 games, and his command has occasionally disappeared.
The Cardinals also own the stronger overall record and home-field advantage. They should not be treated as an easy opponent simply because Arizona starts the pitcher with the lower ERA.
The price accounts for those concerns. At -104, Arizona only needs to win slightly more than half the time for the wager to justify the risk.
Spread Pick: Arizona Diamondbacks -1.5 (+162)
Arizona -1.5 offers substantial plus-money upside but is a higher-variance extension of the moneyline. The Diamondbacks must convert more of their scoring opportunities than they did Monday.
Leahy's 1.57 WHIP gives Arizona a realistic path to building a multi-run inning. He has allowed at least seven hits in four of his last five starts and has surrendered three or more earned runs in three consecutive appearances.
The top of the Diamondbacks order should create repeated pressure. Carroll, Marte, and Perdomo combine contact, patience, and speed, making it difficult for Leahy to work through clean innings.
Rodriguez provides the run-prevention foundation required for a multi-run Arizona victory. If he allows two or fewer runs across six or seven innings, the Diamondbacks will not need an unusually large offensive total to cover.
Arizona's bullpen prevents the run line from becoming the best bet. Diamondbacks relievers own a collective ERA above four and have not consistently protected narrow leads.
St. Louis also possesses enough late-game offense to turn a three-run deficit into a one-run result. Herrera, Walker, Wetherholt, Burleson, and Winn can punish a middle reliever who lacks command.
The Cardinals' bullpen was sharp Monday, but Leahy may expose it earlier Tuesday. If Arizona forces him out during the fifth inning, St. Louis will need four or more relief innings after using its primary late-game arms in the opener.
Scores such as 5-3, 6-3, or 6-4 fit the Arizona run-line position. The plus-money return is attractive, but the moneyline remains the safer and stronger selection.
Total Pick: Under 8.5 (-106)
The Under 8.5 remains the preferred total, although it is not as secure as the original analysis suggested. Rodriguez's underlying numbers and the recent St. Louis offence create meaningful scoring risk.
The strongest Under argument is Rodriguez's consistent run prevention. He has allowed only 24 earned runs across 88.1 innings and has held opponents to one earned run or fewer in three of his last four starts.
Busch Stadium also reduces home-run production compared with many National League parks. Both teams may need to build rallies through consecutive hits rather than relying on easy power.
Arizona has played 41 Unders against 33 Overs this season. The Diamondbacks have also gone Under in seven of their last 10 games.
The series opener produced only five total runs despite 15 combined hits. Both teams reached base but struggled to turn traffic into sustained scoring.
Leahy creates the primary threat to the Under. His 1.57 WHIP and recent hit totals could allow Arizona to score four or five runs before reaching the middle innings.
St. Louis has also been hitting well. The Cardinals' .288 average over the last 10 games gives them a realistic opportunity to contribute three or four runs against Rodriguez and Arizona's bullpen.
Neither bullpen is elite. Arizona and St. Louis both carry relief ERAs slightly above four, creating the possibility of late scoring after a low-scoring opening five innings.
The total still provides enough room for a competitive game. A 4-3, 5-3, or 4-2 result would cash the Under, while a 5-4 final would defeat it.
Top Player Prop Picks
Eduardo Rodriguez Over 4.5 Strikeouts (-112 at FanDuel) Rodriguez has recorded 65 strikeouts across 88.1 innings. He averages 4.3 strikeouts per start and needs five to clear the listed number.
The left-hander recorded five strikeouts during each of his last two starts in which he completed at least six innings. He also struck out six against San Francisco and seven against Pittsburgh earlier this season.
St. Louis does not carry an extreme team strikeout rate, but the lineup contains enough swing-and-miss to give Rodriguez opportunities. Walker, Jordan, Pagés, Velázquez, and several supporting hitters can be vulnerable against quality secondary pitches.
Rodriguez should also receive the workload required to reach five. He completed seven innings in his latest start and has worked at least six innings in three of his last four appearances.
His command is the greatest risk. Rodriguez issued five walks in only 2.2 innings against Cincinnati, showing how an elevated pitch count can create an early exit.
The near-even price compensates for that volatility. Five strikeouts across six competitive innings is a realistic projection against the Cardinals.
Iván Herrera Over 1.5 Total Bases (+118) Herrera has produced excellent recent numbers against left-handed pitching. He is batting .333 with a .600 slugging percentage and 1.100 OPS over his last 60 plate appearances against southpaws.
The right-handed hitter receives the platoon advantage against Rodriguez. Herrera has consistently handled fastballs and changeups from left-handers while generating strong contact in the air.
Rodriguez has allowed right-handed hitters to elevate the ball frequently. That creates extra-base potential for a hitter who already owns 10 home runs and an .834 OPS.
Herrera homered Sunday against Kansas City and added an RBI single Friday. His recent power gives him a direct path to clearing the total with one swing.
A double, triple, or home run would cash the prop. Herrera can also reach the number through two singles.
The plus-money price is preferable to laying -235 or more on a basic one-hit market. Herrera's platoon advantage and current contact quality support the Over.
Kyle Leahy Over 3.5 Strikeouts (-134 at FanDuel) Leahy averages 4.2 strikeouts per start and has recorded at least four in nine of his 14 appearances.
The right-hander produced a season-high seven strikeouts against San Diego during his latest outing. He also recorded five against Minnesota and five against Milwaukee earlier this month.
Arizona does not strike out at an extreme rate, but Leahy should have enough workload to create four opportunities. He has completed at least five innings in six of his last seven starts.
The Diamondbacks also have several hitters who can generate strikeouts when pursuing extra-base damage. Troy, Gurriel, Smith, Moreno, and the lower portion of the order provide Leahy with potential swing-and-miss matchups.
Leahy can allow hits and runs while still clearing the strikeout line. His recent starts demonstrate that the two outcomes are not mutually exclusive.
The price is moderately expensive, but four strikeouts remains below his recent production and season average. Another five- or six-inning appearance should give Leahy enough chances to cash the Over.
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