Baltimore Orioles vs Chicago White Sox Picks and Prediction, September, 15, 2025
Use Code WWWC The Baltimore Orioles face the Chicago White Sox with both teams looking to wrap up the season on a high note. The Orioles have a 69-80 record, and with three losses in a row, they have the worst record in the American League East Division. The White Sox are 57-93, and with three losses in a row, they have the worst record in the American League. Who will win this game? Check out our Orioles vs White Sox prediction!
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Baltimore hopes Bradish helps out awful lineup
The Orioles are having a rough season and look poised to finish the season with the worst record in their division. Kyle Bradish is one of the bright spots as he’s allowed only five runs in 17 innings pitched while tossing 21 strikeouts. Moreover, with a 210 expected opponent Batting Average, a 32.3 Strikeout Rate, and a 2.65 expected ERA, opponents are making minimal contact and struggling to drive in runs against Bradish this season.
Bradish has stepped up but the lineup has let the Orioles down this season, scoring only 4.28 runs per game. Ryan O’Hearn is slashing .283/.374/.463 with 13 home runs and 144 total bases, while Gunnar Henderson is slashing .270/.345/.442 with 16 home runs and 232 total bases, but the rest of the lineup has struggled. Only three active batters have an OPS+ over 100, and opposing pitchers can limit the top-heavy lineup as a result.
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White Sox hope Burke and lineup improve
The White Sox are having a season to forget and look to end a rough season on a high note. Sean Burke will start the upcoming game and he looks to improve on what’s been a rough season on the mound as he’s allowed 70 runs in 122 innings pitched. Moreover, with a .483 expected opponent Slugging Percentage, a 10.5 Barrel Percentage, and a 5.18 expected ERA, opponents are making hard contact and driving in runs at will against Burke this season.
Burke has struggled but the lineup has let the White Sox down, scoring only 4.01 runs per game with only three runs in the last three games. Mike Tauchman is slashing .267/.355/.403 with 128 total bases, while Andrew Benintendi is slashing .243/.306/.431 with 19 home runs and 177 total bases but the rest of the lineup has struggled. Only three active batters have an OPS+ over 100, and opposing pitchers can eliminate the hapless lineup as a result.
Orioles vs White Sox Prediction
Money Line Pick for Orioles vs. White Sox
- Orioles (-140) (4 Units)
The White Sox look to step up at home, but the Orioles have one of their best pitchers on the mound and look to take over this game from the first inning. The Orioles should drive in runs with ease against Sean Burke, who has allowed 70 runs in 122 innings pitched, with Ryan O’Hearn, Gunnar Henderson, and the rest of the batting order making contact and putting together great plate appearances. The Orioles should limit a While Sox lineup that averages only 4.01 runs per game, with Kyle Bradish pitching multiple strong innings to hand the ball over to the bullpen with the lead. The Orioles should win the game with a strong performance on the road.
Over/Under Pick for Orioles vs. White Sox
- Under 8.5 (5 Units)
Both teams have awful lineups, and this game looks to be a low-scoring one from the first pitch. The White Sox should limit the Orioles lineup, which averages only 4.28 runs per game, with Sean Burke pitching multiple strong innings with weak contact off the bat. The Orioles, should eliminate and potentially shut out the White Sox, who have scored only three runs in their last three games, with Kyle Bradish, who has allowed only five runs in their last 17 innings pitched, tossing multiple scoreless innings with a surplus of strikeouts. The Under should cover in a low-scoring game with both starting pitchers stepping up.
- Take the Under on 8.5 runs.
The Orioles face the White Sox with both teams looking to wrap up awful seasons on a high note.
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