Baltimore Orioles vs Los Angeles Angels Picks, Prediction, Odds, and Line Movement for Monday June 22 2026

By: Al MacMillan Published 06/22/2026, 04:21 PM ET
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Baltimore visits Los Angeles with updated picks, pitching analysis, and top MLB player props for Monday night.

Best Available Odds

Best Moneyline Odds: Baltimore Orioles (-157) / Los Angeles Angels (+140)

Best Spread Odds: Baltimore Orioles -1.5 (+104) / Los Angeles Angels +1.5 (-119)

Best Total Odds: Over 9.0 (+102) / Under 9.0 (-119)

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Game Info

Date: Monday, June 22, 2026

Time: 9:38 PM EDT

Location: Angel Stadium, Anaheim, CA

TV: MASN, ABTV

Baltimore Orioles vs Los Angeles Angels Preview

The Baltimore Orioles enter Monday at 37-42 after winning two consecutive games and taking two of three from the Los Angeles Dodgers. Baltimore followed a 6-5 series-opening loss with a 3-2 victory Saturday and a dominant 12-1 win Sunday.

The Orioles produced four home runs in the finale. Colton Cowser collected three hits, a home run, and four RBIs, while Taylor Ward, Pete Alonso, and Blaze Alexander also went deep.

Baltimore scored 20 runs during the three-game series against a Dodgers team with one of baseball's strongest overall records. The lineup has now generated five or more runs in three of its last five games.

Alonso leads Baltimore with 18 home runs and 52 RBIs. He enters after hitting a three-run homer Sunday and has supplied the most consistent power presence in the middle of the order.

Alexander has become one of Baltimore's hottest hitters. He is batting above .400 over his last five weeks and enters Monday with a .429 average and .714 slugging percentage across his last 15 games.

The Orioles remain without several important players. Adley Rutschman is on the concussion injured list, Ryan Mountcastle remains sidelined with a fractured foot, and Jackson Holliday is day-to-day with a groin issue.

Baltimore's pitching depth has also been reduced by injuries to Chris Bassitt, Dean Kremer, Cade Povich, Zach Eflin, and several relievers. Kremer and Povich have started rehabilitation assignments, but neither is available for Monday's series opener.

The Los Angeles Angels enter at 32-47 and remain in last place in the AL West. Los Angeles has won two straight games after defeating the Athletics 7-0 on Saturday and 9-7 on Sunday.

The Angels displayed significant power during the weekend. Rookie Denzer Guzman homered in three consecutive games, while Zach Neto delivered a two-run homer in the ninth inning Sunday to complete the comeback victory.

Los Angeles has scored 27 runs over its last three games. The Angels lost Friday's opener 12-11 before responding with consecutive victories, showing that the offense can remain dangerous despite the club's overall record.

Neto leads the Angels with 17 home runs and a .457 slugging percentage. Logan O'Hoppe has also heated up, going 15-for-34 with four doubles, two home runs, and seven RBIs over his last 10 games.

The Angels are playing without Mike Trout, who is on the injured list with a hamstring strain. Jorge Soler, Adam Frazier, Grayson Rodriguez, Yoรกn Moncada, and Travis d'Arnaud are also unavailable.

The injuries remove several established hitters from the lineup, but Neto, O'Hoppe, Nolan Schanuel, Jo Adell, Vaughn Grissom, Guzman, and Oswald Peraza give Los Angeles enough power and contact ability to challenge an inconsistent Baltimore pitching staff.

Starting Pitchers and Pitching Matchup

The Orioles will start right-hander Kyle Bradish, who enters at 4-7 with a 4.00 ERA, 1.51 WHIP, and 85 strikeouts across 81 innings.

Bradish is coming off his best performance of the season. He recorded a career-high 12 strikeouts across 7.2 innings against Seattle, allowing only one earned run on five hits and two walks.

The outing represented a major improvement after Bradish had allowed five runs and completed only four innings in each of his previous two starts. His ability to work into the eighth inning also provided valuable rest for Baltimore's bullpen.

Bradish owns a 3.15 ERA across his last seven starts. His strikeout ability has remained one of his strongest attributes, with 40 strikeouts across 40 innings during that stretch.

Control remains his primary weakness. Bradish has issued 41 walks and carries a WHIP above 1.50, allowing opponents to create scoring opportunities even when they are not producing consistent hard contact.

His road results have also been less effective than his overall numbers. Bradish owns a 5.09 ERA away from Baltimore and has allowed road opponents to bat above .320.

The Angels can challenge those control problems through Schanuel, Neto, O'Hoppe, and Grissom. Los Angeles has also scored first in several recent games, making Bradish's opening innings particularly important.

Bradish's swing-and-miss ability creates a favourable counterargument. The Angels carry one of baseball's highest strikeout rates and have recorded the third-most strikeouts against right-handed pitching over the last month.

The Angels will start left-hander Sam Aldegheri, who enters at 2-2 with a 4.50 ERA, 1.55 WHIP, and 13 strikeouts across six appearances.

Aldegheri has made only three starts this season. He has not completed six innings in any appearance and averages approximately four innings per start.

The left-hander delivered his best start June 12 against Tampa Bay, allowing one earned run on three hits across five innings. He struck out four but also issued three walks.

Aldegheri struggled badly during his latest outing against Arizona. He allowed six earned runs on six hits and three walks across three innings, recording only one strikeout in an 8-1 loss.

He has recorded only 13 strikeouts and has not demonstrated the swing-and-miss production required to consistently escape innings with runners on base. His 1.55 WHIP creates additional risk against a Baltimore lineup that just punished the Dodgers.

Baltimore is only 7-14 in games started by opposing left-handers, but that record does not automatically make Aldegheri a favourable matchup. He must navigate Alonso, Alexander, Ward, Tyler O'Neill, Coby Mayo, and other right-handed hitters while avoiding an early exit.

The Angels bullpen becomes an important part of the matchup because Aldegheri is unlikely to work deep. Los Angeles relievers carry a collective ERA near 4.65, placing the unit near the bottom of the league.

Game Thesis: Baltimore has the superior starting pitcher, the hotter collection of middle-order hitters, and the more favourable path against an inexperienced starter backed by a vulnerable bullpen. Bradish's road performance and control problems give Los Angeles a realistic chance to contribute several runs, but Aldegheri's limited workload creates too much pressure on the Angels' relief staff. Baltimore should generate enough offense to win by multiple runs in a game capable of reaching double digits.

Moneyline Pick: Baltimore Orioles (-157)

Baltimore is the preferred moneyline side. The Orioles enter after winning a series against the Dodgers and now face a 32-47 Angels team missing several established players.

Bradish provides Baltimore with the more dependable starting option. He has pitched to a 3.15 ERA over his last seven appearances and enters after producing 12 strikeouts across 7.2 innings.

Aldegheri has completed only 24 innings across six appearances. His 1.55 WHIP and limited strikeout production create a difficult matchup against an Orioles lineup that can combine walks, contact, and home-run power.

The Orioles also possess the deeper available batting order. Alonso, Cowser, Ward, Alexander, Henderson, Basallo, O'Neill, and Mayo provide multiple ways to attack a left-handed starter.

Baltimore's struggles against left-handed starters prevent the moneyline from becoming automatic. The Orioles have gone 7-14 in those games, and Bradish's road ERA creates legitimate volatility.

The individual pitching matchup still favours Baltimore. Bradish can miss enough bats to limit the Angels, while Aldegheri and the Los Angeles bullpen must survive several innings against a lineup coming off a four-homer performance.

โญ Best Bet - Spread Pick: Baltimore Orioles -1.5 (+104)

Baltimore -1.5 is the strongest game wager. The run line offers a plus-money price in a matchup where the Orioles can create separation against both the starting pitcher and bullpen.

Aldegheri allowed six earned runs in only three innings during his latest start. He has not completed six innings this season, making it likely that Los Angeles will need at least four innings from its relief staff.

The Angels bullpen enters with an ERA near 4.65. That creates scoring opportunities throughout the game rather than limiting Baltimore's advantage to Aldegheri's first two trips through the lineup.

Alexander and Alonso are both swinging the bat well, while Cowser and Ward enter after major performances against the Dodgers. Baltimore does not need every hitter to contribute to build a multi-run lead.

Bradish's control and road numbers introduce risk. Los Angeles has scored 27 runs over its last three games and can produce home runs through Neto, O'Hoppe, Guzman, and Adell.

The Orioles should still have enough offensive opportunities to overcome three or four Angels runs. Scores such as 7-4, 8-5, or 6-3 fit the pitching matchup and give Baltimore the required two-run margin.

Total Pick: Over 9.0 (+102)

The Over 9.0 is preferable to the original Under recommendation. Both teams enter with improving offenses, and neither pitching staff can be treated as completely reliable.

Baltimore scored 20 runs during its weekend series against Los Angeles. The Orioles hit four home runs Sunday and now face a starter who surrendered six earned runs during his latest appearance.

Aldegheri's limited workload also supports additional scoring opportunities. He has averaged only four innings per start and is backed by one of the league's less effective bullpens.

Los Angeles can contribute against Bradish. The right-hander owns a road ERA above five, carries a 1.51 WHIP, and has issued 41 walks across 81 innings.

The Angels scored 11, seven, and nine runs during their final three games against the Athletics. Neto and Guzman supplied late home runs Sunday, while O'Hoppe has been one of baseball's hotter catchers over the last 10 games.

The missing hitters on both teams create some resistance to the Over, particularly with Trout and Rutschman unavailable. Bradish also demonstrated his ceiling by dominating Seattle during his latest start.

The available plus-money price and nine-run push protection make the Over worthwhile. A Baltimore victory around 7-4 or 6-5 would clear the total, while a 6-3 or 5-4 final would return the stake.

Top Player Prop Picks

Kyle Bradish Over 6.5 Strikeouts (-110) Bradish enters with 85 strikeouts across 81 innings and has demonstrated a ceiling well above this number. He struck out a career-high 12 Mariners during his latest start and recorded 10 strikeouts against the Athletics earlier this season.

The Angels have one of baseball's highest team strikeout rates. Their 24.8% rate ranks near the bottom of the league, and they have accumulated the third-most strikeouts against right-handed pitchers over the last 30 days.

Bradish should also have sufficient workload to reach seven strikeouts. Baltimore allowed him to throw into the eighth inning against Seattle, and the Orioles benefit whenever he can protect their injury-depleted pitching staff.

Walks can raise his pitch count and force an early exit, but the Angels' swing-and-miss profile should generate enough opportunities. Six or more innings with his normal strikeout rate would place Bradish in position to clear 6.5.

Blaze Alexander Over 1.5 Total Bases (+175) Alexander enters as Baltimore's hottest hitter. He is batting .429 with a .714 slugging percentage across his last 15 games and .388 with a .625 slugging percentage over his last 30.

He has cleared his total-bases line in 12 of his last 15 games. Alexander has produced 18 hits, eight RBIs, two home runs, and two stolen bases during the shorter 15-game sample.

The right-handed hitter receives the platoon advantage against Aldegheri. The Angels starter has allowed nine hits and seven earned runs across eight innings during his last two starts.

Alexander also homered Sunday against the Dodgers and should receive multiple opportunities against Los Angeles relievers after Aldegheri exits. A double, two singles, or another home run would cash the plus-money prop.

Nolan Schanuel Over 1.5 Total Bases (+176) Schanuel enters batting .258 with a .327 on-base percentage. He has accumulated five total bases over his last three games and remains one of Los Angeles' more dependable contact hitters.

He has cleared his total-bases line in 15 of his last 20 home games. The plus-money price provides value for a hitter who should bat near the top of the order and receive four or five plate appearances.

Bradish's strikeout ability creates a difficult matchup, but his road performance has been much less reliable. He owns a 5.09 road ERA, a 1.51 overall WHIP, and has allowed opponents to create frequent traffic through walks and hits.

Schanuel does not need to produce a home run to clear the line. Two singles or one extra-base hit would be enough, and his lineup position should provide repeated opportunities before Baltimore reaches its bullpen.

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