Baltimore Orioles vs New York Yankees Prediction and Picks - September 27, 2025

By: Dean Whitaker Published 09/27/2025, 05:00 AM ET
Aaron Judge looks to lead the Yankees over the Orioles
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American League East MLB action on Saturday afternoon, we have a Baltimore Orioles vs New York Yankees Prediction ready to go. The Orioles are just playing out the string as they have gone 75-84 on the year. The Yankees are in a battle for first place in the AL East as they are currently tied atop the division with Toronto. Can the Yankees grab a huge win tonight? Read on to see our Orioles vs Yankees prediction.

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Orioles Hope To Spoil The Party

Baltimore dropped Friday’s contest 8-4 after falling into an early hole that starter Trevor Rogers couldn’t climb out of. Rogers allowed six runs, including three homers, in just three innings of work. Jordan Westburg provided the highlight for the Orioles with a three-run homer in the sixth inning, and Tyler O’Neill added a solo blast, but the lineup couldn’t cash in on several scoring chances. The Orioles went just 1-for-10 with runners in scoring position, which proved costly against a Yankees team that thrived on timely hits.

This loss continued a difficult stretch for Baltimore, which has struggled to find consistency in September. Despite flashes of offensive power from young standouts like Gunnar Henderson and Coby Mayo, the Orioles have been undone by inconsistent pitching and an inability to string together rallies. Even with Friday’s defeat, Baltimore has remained competitive, as their ability to score in bursts makes them dangerous in any game. However, their pitching depth has been tested down the stretch.

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For Saturday’s matchup, the Orioles are set to start veteran right-hander Tomoyuki Sugano, who enters at 10-9 with a 4.54 ERA. Sugano has shown stretches of effectiveness, but he has also been prone to giving up the long ball, something the Yankees punished Rogers with on Friday. Baltimore will need him to keep the ball in the park and give length to help save the bullpen for the series finale. Offensively, the Orioles will look for Westburg, O’Neill, and Henderson to spark the lineup and apply pressure on Schlittler early.

Yankees Stay Tied Atop The AL East

The Yankees took control of Friday’s matchup with an 8-4 win over Baltimore, using the long ball to do most of the damage. Giancarlo Stanton had a massive night, blasting two home runs and driving in five runs, while Aaron Judge added his 52nd homer of the season. Starter Will Warren allowed four runs over five innings, but the bullpen shut the door over the final four frames to preserve the victory. The win evened the series and kept New York firmly in the hunt for the American League East title.

This victory showcased the Yankees’ power-heavy approach, as they finished with three home runs on the night. Judge continues to be the centerpiece of the offense, while Stanton’s resurgence gives the middle of the order more protection. New York has now won six of its last eight games, showing strong momentum in the final week of the regular season. With the Blue Jays holding the head-to-head tiebreaker in the division, the Yankees know they need to stack wins if they want a shot at the crown.

On Saturday, the Yankees will hand the ball to right-hander Cam Schlittler, who enters at 3-3 with a 3.27 ERA. Schlittler has been effective in his limited starts, showing command and poise in high-pressure spots. He’ll be tasked with keeping the Orioles’ power bats under control while the Yankees’ offense looks to build on last night’s fireworks. With Judge and Stanton swinging the bats well, New York will aim to put pressure on Baltimore’s starter early and back Schlittler with run support.

Baltimore Orioles vs New York Yankees Pick

Orioles vs Yankees Moneyline Pick

  • NY Yankees -1.5 (5 Units)

The Yankees come into Saturday with momentum after Friday’s 8-4 win, and their offensive firepower looks primed to carry over. Giancarlo Stanton is swinging a hot bat after belting two homers and driving in five runs, while Aaron Judge continues to crush pitching with 52 long balls on the year. Facing Baltimore starter Tomoyuki Sugano, who owns a 4.54 ERA and has been vulnerable to the home run ball, New York’s lineup has a clear edge. The Yankees have also won six of their last eight games, giving them strong form as they push for the AL East crown.

On the pitching side, Cam Schlittler has provided steady outings for New York, posting a 3.27 ERA while limiting damage in tight situations. He matches up well against an Orioles lineup that struggled with runners in scoring position on Friday, going just 1-for-10. Baltimore’s recent inconsistency on the mound and at the plate leaves them in a tough spot, especially against a Yankees team motivated to keep pace in the division race. With their bats locked in and a capable starter on the mound, New York has a strong chance to cover the -1.5 run line.

Orioles vs Yankees Over/Under Pick

  • Under 9 (4 Units)

With Saturday’s total set at 9, the Under looks appealing given the pitching matchup and recent trends. Yankees starter Cam Schlittler has been reliable with a 3.27 ERA, and Baltimore’s Tomoyuki Sugano, while inconsistent, is capable of limiting damage when he keeps the ball in the park. Both offenses showed power on Friday, but replicating that level of production on back-to-back nights is less likely, especially with cooler late-September conditions in New York. If the starters can provide quality innings and the bullpens hold steady, this game has a strong chance of staying under the number.

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