Baltimore Orioles vs Pittsburgh Pirates Picks and Predictions for Friday April 3 2026

By: Kim Smith Updated 04/03/2026, 11:00 AM ET
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The Baltimore Orioles head to PNC Park in Pittsburgh, Pennsylvania, for an afternoon clash with the Pittsburgh Pirates, with first pitch set for 4:12 PM on April 3, 2026. The game will air on MLB.TV. Baltimore is listed as a slight favorite at -122 on the moneyline, while Pittsburgh comes back at +102. The total is set at 8, with the over at -115 and the under at -105. On the run line, the Orioles are -1.5 (+135), while the Pirates are +1.5 (-163). With both teams sitting at .500 early in the season, this matchup presents an intriguing opportunity for bettors. Be sure to check out free MLB picks for more daily betting insight.

Starting Pitchers Breakdown

Baltimore is expected to hand the ball to Kyle Bradish, while Pittsburgh will counter with Mitch Keller. Bradish comes into this game with a 0-1 record, carrying a 3.86 ERA and a 1.07 WHIP across 4.2 innings. In that outing, he limited opponents to just two hits while striking out four, but issued three walks and allowed one home run. Keller, on the other hand, has been excellent to start the season, posting a 0.00 ERA and a 0.50 WHIP over 6.0 innings. He allowed only three hits, struck out three, and did not walk a batter or give up a home run. Based on early results, Pittsburgh appears to have the edge on the mound.

Baltimore Aiming for Consistency

The Orioles enter this contest with a 3-3 record and will be opening their road schedule at 0-0 away from home. In their last five games, Baltimore has picked up wins over Texas by an 8-3 score and Minnesota by an 8-6 margin, but they have also dropped games to Texas by scores of 8-5 and 5-2, along with a 4-1 loss to Minnesota. This stretch highlights a team that has been competitive in most outings but has struggled to string together consistent results.

Offensively, Baltimore is hitting .255 with 26 runs and 50 hits, along with five home runs. Their on-base percentage sits at .332, paired with a .383 slugging percentage. On the pitching side, they hold a 4.33 ERA and a 1.37 WHIP, allowing opponents to hit .246. The staff has recorded 58 strikeouts against 23 walks, showing a reasonable balance but also allowing opportunities for opposing hitters.

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One of the more encouraging aspects for Baltimore has been its ability to generate offense. With a solid batting average and consistent on-base production, they have been able to create scoring chances in most games, keeping them competitive even when the pitching has not been at its best.

Pittsburgh Bringing Power to the Plate

The Pirates come into this matchup with a 3-3 record and will be playing their first home game of the season. Over their last five games, Pittsburgh has posted back-to-back 8-3 wins over Cincinnati and also secured a 4-3 extra-inning victory against New York. However, they have also suffered a 2-0 loss to Cincinnati and a 4-2 extra-inning defeat to New York. This run of results shows a team capable of winning in different ways, whether through offense or tight pitching performances.

At the plate, Pittsburgh is hitting .231 with 29 runs and 50 hits, including ten home runs. Their on-base percentage is .316, complemented by a .398 slugging percentage. On the mound, the Pirates have a 3.67 ERA and a 1.35 WHIP while holding opponents to a .209 batting average. They have recorded 62 strikeouts but have also issued 32 walks, indicating some inconsistency with control.

The biggest strength for Pittsburgh has been its power hitting. With ten home runs already, they have shown the ability to score quickly and change games with one swing. When paired with a pitching staff that has limited opponents to a low batting average, it gives them a strong overall profile in this matchup.

Baltimore Orioles vs Pittsburgh Pirates Picks and Prediction

Baltimore Orioles vs Pittsburgh Pirates Pick

Pick: Pittsburgh Pirates Moneyline

Pittsburgh holds the advantage on the mound with Keller’s dominant early performance, including a 0.00 ERA and a very low WHIP. While Baltimore has been solid offensively, the Pirates have displayed more power with ten home runs and a higher slugging percentage. That combination of stronger starting pitching and greater offensive impact gives Pittsburgh the edge in what should be a closely contested game.

Baltimore Orioles vs Pittsburgh Pirates Total Pick

Pick: Under 8

I am leaning toward the under in this matchup because both teams have shown the ability to pitch effectively. Pittsburgh’s staff has limited opponents to a .209 batting average, and Keller’s early form suggests he can keep scoring in check. Baltimore has been capable offensively, but this game projects to be more controlled on the mound. With the total set at 8, the under looks like the better option.

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Final Score Prediction: Pittsburgh Pirates 4 – Baltimore Orioles 3

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