Baltimore Orioles vs Pittsburgh Pirates Picks and Predictions for Sunday, April 5, 2026

By: Cameron Ross Published 04/05/2026, 06:05 AM ET
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The Baltimore Orioles will be on the road Sunday afternoon with a 1:35 PM game inside PNC Park in Pittsburgh against the Pittsburgh Pirates, and we have you ready to roll with our Baltimore vs Pittsburgh prediction. Baltimore comes into this game with 3 wins and 4 losses on the year. Pittsburgh stays home Sunday with 4 wins and 3 losses on the year. Baltimore has lost 3 of the last 4 overall following the loss in game 1 of this set. Pittsburgh has won 4 of the last 5, including 3 in a row, after the win in the first game of this series. Read more about this Chicago vs Miami prediction! Struggling with handicapping? Try our MLB Predictions!

Baltimore looks to get to .500

The Baltimore Orioles' offense has been stout this season with a .257 team batting average. Baltimore has scored thirty runs on 59 hits through seven games played. The Orioles offense has compiled a .336 OBP and a .391 team slugging percentage. The Baltimore pitching has been the team's biggest issue, with a 4.50 team ERA. Kyle Bradish got to start and took the loss for Baltimore in Game 1 of this series, giving up four runs on six hits across 6 innings of work. The Baltimore bullpen gave up one more run over the final four innings of the game. Gunnar Henderson carried the Baltimore offense in their last outing with 3 hits in 5 at-bats to drive in 2 runs.

Adley Rutschman leads the Baltimore offense this season with a .333 batting average. Taylor Ward has a .290 batting average, and Dylan Beavers has a .318 batting average. Gunnar Hnederson has a .242 batting average and leads the team with 2 homeruns and 6 RBIS on the season.

Key Injury Report for Baltimore:

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  • Maverick Handley (Day-To-Day)
  • Keagan Gillies  ( 7 Day IL)
  • Jeston Kjerstad (10-Day IL)
  • Andrew Kittredge (15-Day IL)
  • Hans Crouse (7-Day IL)

Pittsburgh tries to keep it rolling

Offensively, Pittsburgh has been lackluster this season with a .230 batting average. The pirates have scored just 30-4 runs on 56 hits this season. The Pittsburgh offense has compiled a .320 OBP and a .391 team slugging percentage. Pittsburgh has picked up the offense as of late, as the Pirates have scored 25 total runs across their last four victories. Mitch Keller got the start and won for Pittsburgh in Game 1 of this series, giving up two runs on six hits across 6 innings of work. The Pittsburgh bullpen allowed two runs on three hits over the final five innings of the game. Pittsburgh had a balanced offensive attack in Game 1 of this series, with five different players driving in one run each.

Ryan O’Hearn leads the Pittsburgh offense this season with a .360 batting average and 7 RBIs. O'Neill Cruz has a .290 batting average this season to go along with the team-leading three home runs. Brandon Lowe has a .280 batting average, and Bryan Reynolds has chipped in heavily with a .235 batting average this season.

Key Injury Report for Pittsburgh:

  • Anthony Solometo (Day-To-Day)
  • Chris Devenski (Out)
  • Jared Jones (60-Day IL)
  • Oddainer Mosqueda (60-Day IL)

Baltimore vs Pittsburgh Pick

  • Baltimore vs Pittsburgh Spread Pick

Pittsburgh is having the better year coming into Sunday and will continue that trend in this game. Pittsburgh has the better arm on the mound and the home crowd behind them. Look for the Pirates to do the work on Sunday, leading to the home win against the Orioles.

  • Baltimore vs Pittsburgh Over/Under Pick

Game 1 of this series saw a ton of runs, and Sunday's game will bring the same. With a bad pitcher on the mound look for the Pirates to do the work leading to the win. Pittsburgh will get the win in this game as the total goes over the number on Sunday in Pittsburgh.

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