Chicago White Sox vs Milwaukee Brewers Picks and Prediction for Sunday March 29 2026

By: Dylan Hellebrand Published 03/29/2026, 05:45 AM ET
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The Chicago White Sox come into this game at 0–1 and will take on the Milwaukee Brewers, who are 1–0, at American Family Field in Milwaukee, Wisconsin. It’s the final game of the series between the two teams, and both sides will be looking to close out the set on a strong note. Get involved in the action with our free MLB picks.

Chicago vs. Milwaukee Game Information

  • March 29, 2026
  • 2:10pm EST
  • American Family Field
  • MLB.TV/Chicago Sports Network/Brewers.TV

Milwaukee Form & Recent Results

Milwaukee heads into this matchup feeling confident after a statement win in their Opening Day game against the White Sox, rolling to a 14-2 blowout. The Brewers’ bats were loud from the start, and Jake Bauers played a big role in the offensive explosion by going 2-for-5 with a home run. He also crossed the plate twice and drove in three runs, giving Milwaukee an early spark and helping them keep their foot on the gas throughout the game. On the mound, rookie Jacob Misiorowski was just as impressive, working five strong innings while allowing only two hits and one earned run. Even though he issued three walks, he more than made up for it by racking up 11 strikeouts, repeatedly overpowering Chicago hitters and setting the tone for the rest of the afternoon.

Last season, the Brewers had plenty of proof that this kind of production isn’t a fluke. Christian Yelich paced the team in home runs with 29 and was also their top run producer, finishing with 103 RBIs. Jackson Chourio added even more power behind him, ending the year with 21 home runs of his own and giving Milwaukee another dangerous bat in the lineup. For pure consistency at the plate, Sal Frelick and Brice Turang were the team’s best in batting average, each hitting .288. Milwaukee’s offense was simply too much for a White Sox squad that struggled badly last season, and the Brewers will try to carry that momentum into Sunday afternoon as they close out the series with another strong performance.

Chicago Form & Recent Results

Chicago heads into this game still trying to shake off a rough start to the season after getting outplayed on both sides of the ball in a 14–2 Opening Day loss to the Brewers. Milwaukee’s bats were loud early and often, and the White Sox never really found a way to slow them down or answer back with consistent offense of their own. One bright spot for Chicago, though, was Chase Meidroth, who went 1-for-2 and made his one hit count by crushing a home run. He also crossed the plate himself and drove in a run, giving the White Sox at least a small reminder that there’s power in this lineup even when the rest of the game gets away from them.

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Lenyn Sosa was one of Chicago’s most reliable producers last year and a key reason they were able to generate any steady offense. He led the team in home runs with 22, finished first in RBIs with 75, and also paced the club in batting average at .264, showing he can contribute in more than one way. Colson Montgomery wasn’t far behind in the power department either, finishing second on the team with 21 home runs last year. Even though the White Sox are coming off a tough 60–102 season and aren’t widely expected to take a huge leap forward this season, they’ll be motivated to put that Opening Day result behind them and prove they can compete by stealing a big win in Milwaukee.

Key Stats

  • Chicago’s Munetaka Murakami on Thursday: 1-for-2, 1 run, 1 home run, 1 RBI
  • Milwaukee’s Joey Ortiz on Thursday: 2-for-3, 2 runs, 2 RBIs

Betting Odds & Market Overview:

  • MIL -171 / CHW +141; O/U 8

Chicago vs. Milwaukee Picks and Prediction

Chicago’s pitching got off to a rough start on Opening Day, getting rocked for 14 runs by the Brewers. Now Milwaukee comes into this one looking to keep that momentum going and finish the series with another convincing win. The Brewers will lean on starter Brandon Sproat to set the tone and give them a strong game on the mound, while the White Sox will hand the ball to Anthony Kay and hope he can steady things early. For Chicago, the biggest key is the bats if their offense can finally get going, they’ll have a chance to push back against the early season criticism and show they’re better than what they put on the field in the opener. Final Score Prediction, Milwaukee Brewers win 2-0.

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