Chicago White Sox vs Milwaukee Brewers Picks and Predictions for Thursday, March 26, 2026
Use Code WWWC The Chicago White Sox will be on the road Thursday for an opening day matchup inside American Family Field in Milwaukee, WI, at 2:10 PM against the Milwaukee Brewers, and we have you ready to roll with our Chicago vs Milwaukee prediction. Chicago comes into the 2026 season looking to improve on last year, when they finished among the worst teams in baseball. Milwaukee will look to repeat last year's success, having finished the regular season as the league's number one team. Chicago struggled immensely start to finish last year, finishing the season with sixty wins and 102 losses. The Brewers were phenomenal in 2025, finishing the year 97-65 overall. Read more about this Chicago vs Milwaukee prediction! Struggling with handicapping? Try our MLB Predictions!
Chicago tries to start the year strong
The Chicago White Sox were a bottom-feeder on the offensive side of the MLB a year ago. Chicago ranked 27th in the league with a .232 team batting average. Accompanied by such a poor team batting average, the White Sox mustered a .302 on-base percentage and a .373 team slugging percentage. Chicago scored 647 total runs on 1250 hits last season.
Lenyn Sosa led the way with the Chicago offense last season with a .264 batting average, 22 home runs, and 75 RBIs. Chase Meidroth Chipped in heavily for Chicago with a .253 batting average, and Miguel Vargas added a .234 batting average to go along with sixteen home runs. Andrew Benintendi added a .240 batting average and 20 home runs last year for Chicago, but played in only 116 total games.
Key Injury Report for Chicago:
Get Free $30 Credit for Premium Picks + Exclusive Discounts
Subscribe Now
- Everson Pereira (Day-to-Day)
- Ky Bush (Out)
- Kyle Teel (10-Day IL)
- Prelander Berroa (15-Day IL)
- Brooks Baldwins (10- Day IL)
Milwaukee looks to build off last year
The Milwaukee Brewers were phenomenal on the offensive end a year ago, finishing the season tied for second in the league with a .258 team batting average. Milwaukee boasted 1423 hits and scored 806 total runs last season. The Milwaukee power was resounding as well, with 166 home runs and a .403 team slugging percentage. The Milwaukee pitching was just as prominent as their hitting, as Milwaukee finished second in the league with a 3.58 team ERA.
Sal Frelick led the Milwaukee offense last season with a .288 batting average. Brice Turang chipped in heavily with a .288 batting average as well to go along with the team-leading 168 hits. Christian Yelich returns this season after supplying the power for Milwaukee last year, leading the team with 29 home runs and 103 RBIs. Jackson Chourio was vital for the Brewers last year, compiling a .270 batting average to go along with 21 homers and 78 RBIs in 131 games played.
Key Injury Report for Milwaukee:
- Eduardo Garcia (Day-to-Day)
- Thomas Pannone (Day-to-Day)
- JB Bukauskas (Day-to-Day)
- Craig Yoho (15-Day IL)
Chicago vs Milwaukee Pick
- Chicago vs Milwaukee Spread Pick
The Milwaukee Brewers are the much better team in this matchup and will have no issue on Thursday. The Brewers ranked in the top 5 offensively and on the mound last year, leading to the league's top record. Look for the Brewers to jump out strong on a terrible Chicago team, leading to the victory. Milwaukee is going to control this game on both sides of the ball as they do the work for 9 innings in this matchup. Take the Brewers and start the season with a win as they beat Chicago Thursday afternoon at home.
- Chicago vs Milwaukee Over/Under Pick
Both teams have mediocre pitchers, but Chicago has a terrible offense. Look for the Milwaukee bullpen to do the job as they stifle Chicago from the start. Chicago is going to struggle to score as it did against Milwaukee last season. The Milwaukee offense will do the work, but the Brewers pitching will be the difference Thursday afternoon. Take the under on Thursday as the Milwaukee Brewers open the 2026 season with a win at home.
Never Tried Winners and Whiners? Now Is Your Chance
- Get your first daily picks package for ONLY $1 using coupon code DOLLAR
- If the pick loses, we credit your account with 3 Flex Picks
- If the pick wins, we still give you 1 Flex Pick on the house
- Win or lose, you walk away ahead. One dollar. No catch.
- Check out more MLB predictions
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days
