Cincinnati Reds vs Milwaukee Brewers Prediction and Picks - September 28, 2025
Use Code WWWC Major League Baseball action within the National League Central on Sunday afternoon, and we have a Cincinnati Reds vs Milwaukee Brewers Prediction ready to go. The Reds come in looking to secure a spot in the playoffs, and they have to win this game to do so. The Brewers come in having locked up the top seed in the National League for the upcoming playoffs. Read on to see our Reds vs Brewers prediction.
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Reds Win And They Are In
The Reds kept their playoff hopes alive with a 7-4 win over Milwaukee on Saturday, improving to 83–78 and setting up a win-and-in scenario for Game 162. They jumped ahead early with a 6-run 3rd inning and added an insurance run in the sixth. Cincinnati finished with 10 hits, seven walks, and six RBIs, applying consistent pressure and controlling tempo from the outset. The offense showed balance and patience, drawing out long innings and forcing Milwaukee into early bullpen decisions.
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Andrew Abbott earned the win on Saturday, but Brady Singer will take the ball for Sunday’s finale. With the season on the line, Singer steps into the spotlight looking to deliver a playoff-clinching performance. The bullpen remains a strength behind him: Connor Phillips and Graham Ashcraft bridged the middle innings, Nick Martinez fired two scoreless frames with two strikeouts, and Emilio Pagán closed out the ninth with a clean 1.0 inning for his 32nd save. The staff held Milwaukee scoreless over the final three innings, preserving the lead and showcasing late-game control.
Sunday’s matchup is a win-and-in moment for Cincinnati. With the season series tied 6–6 and the Mets also battling for the final Wild Card spot, the Reds control their own fate. Andújar’s bat remains hot, Stewart delivered in the clutch, and Singer now anchors a staff that’s been sharp down the stretch. One more win punches their ticket — and they’ll enter Game 162 with urgency, depth, and everything on the line.
Brewers Clinch Top Seed In National League
Milwaukee fell 7–4 on Saturday, despite the offensive pedigree often associated with this squad. The Brewers’ starter, Robert Gasser, struggled, giving up multiple baserunners before the big third inning by Cincinnati. Milwaukee managed four runs — including a solo home run by Jackson Chourio — but their bullpen could not contain the Reds’ momentum.
Even with the loss, Milwaukee has already clinched the No. 1 seed in the National League, securing home-field advantage throughout the postseason. This sets the bullpen and rotation planning in a different light — depth and rest take priority over the outcome of today’s game. Offensively, they’ll need production from Christian Yelich, Brice Turang, and Jackson Chourio to bounce back.
For Sunday’s finale, the Brewers are expected to send Freddy Peralta to the mound. He carries a 17–6 record and a 2.68 ERA and has been one of their more reliable pitchers this season. Milwaukee will look for Peralta to pitch deep into the game, limit damage early, and let their offense chip away. With Cincinnati pushing for October, the intensity will be high even if their postseason position is already locked in.
Cincinnati Reds vs Milwaukee Brewers Pick
Reds vs Brewers Moneyline Pick
- Milwaukee -132 (4 Units)
The Brewers have the advantage in Sunday’s finale with Freddy Peralta on the mound, and his consistency makes them a strong play to bounce back. Peralta has been one of Milwaukee’s most reliable arms all season, combining swing-and-miss stuff with the ability to pitch deep into games. Against a Cincinnati lineup that feasted in one inning on Saturday but has struggled with consistency, Peralta’s command and strikeout ability should help keep the Reds in check. With Milwaukee already locked into the postseason, Peralta can focus on fine-tuning for October, while the offense looks to provide him early run support.
At the plate, Milwaukee has the pieces to make life difficult for Cincinnati’s pitching. Jackson Chourio has been a bright spot with his power, Christian Yelich remains the veteran catalyst, and Brice Turang’s speed can create pressure on the bases. After falling behind early on Saturday, the Brewers will look to set the tone with timely hitting and cleaner execution. With Peralta leading the way and the offense capable of producing against Brady Singer, Milwaukee has the tools to close the series with a win and enter the postseason on a high note.
Reds vs Brewers Over/Under Pick
- Under 7.5 (5 Units)
The Under 7.5 looks appealing here with Freddy Peralta and Brady Singer set to start. Both pitchers have been effective in September, with Peralta flashing elite strikeout stuff and Singer keeping opponents off balance by limiting walks and hard contact. Cincinnati’s offense has been hot and cold, often relying on one big inning, while Milwaukee’s bats have been steady but not overwhelming. With both teams playing in a pressure spot — Cincinnati fighting for its Wild Card life and Milwaukee sharpening up for October — this matchup sets up as a low-scoring contest where runs are tough to come by.
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