Cleveland Guardians vs. Seattle Mariners, Picks and Prediction, Sunday, March 29, 2026

By: Bosun Akinpelu Published 03/29/2026, 05:15 AM ET
Guardians vs. Mariners prediction
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Cleveland (1-1) will be trying to pick up their first series win of the season when they visit T-Mobile Park on Sunday night to face Seattle (1-1) in the final game of their four-game series at 7:20 PM. ET. Read on to find out which team picks up the win in this Guardians vs. Mariners prediction. Need some winners this baseball season? Check out our Free MLB Picks.

Slade Cecconi will get the start for the Guardians. He was 7-7 with a 4.30 ERA last season. The Mariners will counter with Emerson Hancock, who was 4-5 with a 4.90 ERA last season.

Cleveland and Seattle split their last 10 meetings.

**This preview was written before Saturday’s game was played.**

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Guardians Trying To Bounce Back From Loss

The Guardians followed up their season-opening win over the Mariners with a loss in the second game of the series. They will try to bounce back from the loss and pick up their first series win of the season when they play on Sunday.

Cleveland is averaging 3.5 runs per game through two games. They have a .235 batting average, a .307 on base percentage, and a .426 slugging percentage.

Rhys Hoskins leads the Guardians with a .500 batting average, while Chase DeLauter leads the team with three home runs and three RBI.

Cleveland is giving up 4.5 runs per game through two games. Opponents have a .155 batting average against them, while their pitching staff has a 4.76 ERA.

In his last start, Cecconi gave up two hits and one run in 2.1 innings, leading to a 6-3 loss to Detroit. He is 0-1 with a 1.50 ERA in one start against Seattle.

Mariners Going For Second Consecutive Win

The Mariners bounced back from their first loss of the season with a win over the Guardians in their last game. They will try to keep the momentum going and pick up their second straight win when they play on Sunday.

Seattle is averaging 4.5 runs per game through two games. They have a .155 batting average, a .269 on base percentage, and a .534 slugging percentage.

Brendan Donovan leads Seattle with a .333 batting average, while Luke Raley has two home runs and three RBI.

Seattle is giving up 3.5 runs per game through two games. Opponents have a .235 batting average against them, while their pitching staff has a 3.50 ERA.

In his last start, Hancock gave up two hits and two runs in two innings, leading to an 8-2 loss to Toronto. He is 2-0 with a 2.19 ERA in two starts against Cleveland.

Guardians vs. Mariners Picks

Money Line Pick for Guardians vs. Mariners

  • Seattle Mariners ML (4 Units)

The Mariners have the edge in this game because they played well offensively in their first two games. They had a lot of success against right-handers, and they’re going up against Cecconi, who struggled on the road last season, giving up nine runs in his last three road starts. With Cleveland’s bullpen also struggling through their first two games, expect them to have a hard time slowing down the Mariners.

Cleveland will struggle offensively because they weren’t very good against right-handers last season, and they’re batting under .200 against them through their first two games. Hancock gave up only two runs in his last three starts and three runs in two starts against the Guardians, so expect him to keep their offense in check. Take Chicago on the money line.

Over/Under Pick for Guardians vs. Mariners

  • Under (4 Units)

The Guardians are averaging 3.5 runs per game through their first two games. They’re batting .190 against right-handers, and they’re going up against a starter who gave up three runs in two starts against them. The Mariners averaged 4.5 runs per game. They’re batting .167 against right-handers, and they’re facing a starter who gave up one run in his lone start against them. Don’t expect these teams to score enough runs to push the score over the total. The Guardians and Mariners played under the total in two of their last three meetings.

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