Colorado Rockies vs. Seattle Mariners Prediction and Picks - Thursday, September 25, 2025

By: David Delano Published 09/25/2025, 04:07 AM ET
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The Seattle Mariners (87-69) close out a three-game home set with the Colorado Rockies (43-113) on Thursday night at T-Mobile Park. Seattle looks to solidify its AL West lead as Colorado continues what has been a historically poor season.

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They still get paid to play

The Rockies enter Thursday with the league’s worst record and rank near the bottom in most offensive and defensive categories. Starting pitcher Bradley Blalock has endured a rough season, carrying a 2-5 record and 9.16 ERA. In his last start, he allowed six runs and two homers against the LA Angels on Sept. 19, but the Rockies won the contest 7-6. Blalock has struggled with the home run ball lately, allowing 10 over his last five starts. He's also given up 79 hits in 55 innings, while walking 21 batters for a 1.82 WHIP. Following him will be a Colorado bullpen that ranks 29th in MLB with a 5.27 ERA.

The Rockies are also dead-last in moneyline profit, showing that even laying prices greater than -200 have still been profitable wagers when fading this team.

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Mariners on fire

Seattle has surged down the stretch and continues to look October-ready as they are in control in the AL West. The Mariners are 48-27 at home on the season and looking to close in on their first division title since 2001.

Thursday's projected starter, Bryan Woo has been one of the AL Cy Young candidates, posting a 15-7 record, 2.94 ERA and 0.93 WHIP. Woo has also only walked 31 batters while striking out 198 in 186.2 innings. At home, Woo is 10-2 with a 2.44 ERA this season.

The Mariners also have one of the most potent offenses in baseball, led by Cal Raleigh (58 HR, 121 RBI) and Julio Rodríguez (31 HR, 94 RBI). Overal,l the Mariners are ninth in moneyline profit this season.

Rockies vs Mariners Predictions

Rockies vs Mariners Side Pick:

  • Mariners -1.5 (5 units)

Sometimes you can't overthink what's right in front of you, and you won't see many mismatches bigger than this one.

The Seattle Mariners enter this matchup having won 14 of their last 15 games and looking like a legit contender to win the American League pennant. On the other side, we have the worst team in baseball, and they'll be sending out a young arm that hasn't experienced much success. Beyond Bradley Blalock’s struggles on the mound is also Colorado’s 29th-ranked bullpen.

With the dominance that the Mariners and Bryan Woo have shown lately, Mariners runline is the only way to go.

Rockies vs Mariners Total Pick:

  • Over 8.5

As dominant as Woo has been this season, he has been dealing with some pec tightness, so I don't expect him to be pushed to deep into this game. With Colorado’s Bradley Blalock on the mound, the Mariners may get to the over themselves, opening the door for the Rockies to add some meaningless runs late off the bullpen as well. Raleigh should go deep at least once against him.

The Mariners won't play this game to tight with their bullpen. Take the over.

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