Houston Astros vs Athletics Picks and Prediction, Sunday, April 5, 2026
Use Code WWWC The Houston Astros face the Athletics with both teams heading in opposite directions to begin this season. The Astros are 6-3 and sit at the top of the American League West Division while the Athletics are 2-6 and at the bottom of the division. Who will win this game? Check out our Astros vs Athletics prediction! Be ready for all the baseball action with our Free MLB predictions.
Houston look for McCullers and potent lineup to end series strong
The Astros are having a great season and look to return to the top of the American League. Lance McCullers will start the upcoming game, and the veteran arm is off to a strong start as he allowed only one run in seven innings pitched.
McCullers has been great but the lineup has carried the Astros so far, scoring 6.12 runs per game with 11 runs in their recent win. Yordan Alvarez has three home runs and 22 total bases while Jose Altuve has two homers and 15 total bases but the rest of the batting order has stepped up as well. Christian Walker has 13 total bases while Carlos Correa and Cam Smith have added two home runs and 22 total bases to add depth to the lineup.
Athletics hope Lopez and lineup step up
The A’s are having a rough start to another rough season that looks like it’s going nowhere, like their relocation plans to Las Vegas. Jacob Lopez will start the upcoming game, and he looks to improve on a rocky start as he’s allowed three runs in four innings pitched.
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Lopez looks to improve but the lineup has let the Athletics down, allowing 4.00 runs per game. Shea Langeliers has five home runs and 24 total bases while Max Muncy has 16 total bases but the rest of the batting order has struggled. Only three batters have an OPS+ over 100 and opposing pitchers can eliminate the hapless lineup as a result.
Astros vs Athletics Pick
Money Line Pick For Astros vs Athletics
- Astros (-110) (4 units)
The Astros are off to a great start, and I see them taking over this game from the first inning. The Astros, who average 6.12 runs per game, should drive in runs at will with Yordan Alvarez, Jose Altuve, and the rest of the lineup making contact and putting together strong plate appearances. The Astros should limit an Athletics lineup that averages only 4.00 runs per game, with Lance McCullers building off a start where he allowed only one run in seven innings and tossing multiple scoreless innings to allow the bullpen to close out the game with the lead. The Astros should win the game with a dominant performance on the road.
Take the Astros money line as road Favorites.
Over/Under Pick For Astros vs Athletics
- Over 10 (4 units)
The Astros are led by one of the best lineups in baseball, and I see this game being a high-scoring one from the opening puck drop. The Athletics should plate multiple baserunners with Shea Langeliers, Max Muncy, and the rest of the lineup making contact and putting together strong plate appearances. The Astros look to build off a game where they scored 11 runs and run up the score with Yordan Alvarez, Jose Altuve, Carlos Correa, and the rest of the batting order swinging for the fences and crushing pitches to drive in runs at will. The Over should cover in a high-scoring game with both lineups stepping up.
Take the Over on 11 goals.
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