Kansas City Royals vs. Los Angeles Angels Pick and Prediction for Tuesday, September 23rd, 2025

By: Adam Rauzino Published 09/23/2025, 11:30 AM ET
Blue Jays vs Angels prediction
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The Kansas City Royals (78-78, 76-80 RL, 68-87-1 O/U) and the Los Angeles Angels (70-86, 81-75 RL, 85-67-3 O/U) resume a three-game series on Tuesday evening, and we have you covered with the prediction. The Royals are going with Cole Ragans. The Angels will answer with Sam Aldegheri. The Angels lead the season series 2-1.

Can the Angels begin their last homestand for the season with a win on Tuesday evening? Check out the Royals vs. Angels prediction. Nobody does it better when it comes to MLB Picks!

Ragans Gets the Nod to Open Series

Cole Ragans is on the rubber on Tuesday. Ragans made his return after a trip on the IL last week and conceded two runs in 3.1 innings against Seattle, ending in a no-decision in a game the Royals won. The southpaw is their ace, but has battled a few injuries this season and was unable to find a groove. He has recorded a 5.16 ERA and a 1.26 WHIP, accompanied by a 2-3 record in 52.1 innings of work on the year. Ragans has weak numbers against Los Angeles, posting a 6.12 ERA and an 0-3 record in 25 innings.

The Kansas City Royals were not able to score runs consistently enough this season and are going to miss the playoffs. They are striving for a .500 record. They dropped a series against the Mariners this week and rebounded by posting a series win against the Blue Jays this week, keeping a potent offense to only 10 runs. The Royals are 35-40 on the road.

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Jac Caglianone is one of K.C.'s top prospects, but has struggled. The 22-year-old has only managed a .552 OPS in 58 games. Michael Massey has a .561 OPS this month. The veteran second baseman has 19 RBIs and a .562 OPS. Maikel Garcia has been one of the most consistent players on this squad. The 25-year-old has seven RBIs this month and has recorded 16 home runs and 71 RBIs. Bobby Witt Jr. has one RBI and a sharp 1.1 OPS against the Angels this season. The star shortstop has managed 82 RBIs on the year.

Kansas City is averaging 3.95 runs on the year, ranking them 28th. The pitching is strong, posting a 3.77 ERA, good for fifth.

Angels Drop Series Against Rockies

Sam Aldegheri was promoted and will get the nod to begin the series on Tuesday evening. This was Soriano’s spot, but he is injured. Aldegheri has made two appearances for the Angels this season and struggled, conceding seven runs in 4.1 innings pitched. He has squandered 19 runs in 17.1 career innings in the big leagues. The southpaw was decent in the minor leagues this season, posting a 3.78 ERA and a 1.36 WHIP in 133.1 innings of work.

The Los Angeles Angels had another disappointing season, although the offense is promising, while the pitching needs improvement. If the pitching can improve, they can contend next season. The Angels are slumping down the stretch. They have dropped nine of their past 10 games as the pitching continues to be exposed. The group was swept by the Brewers and dropped a series in Colorado this week despite yielding just 10 runs in the series. The Angels stand at 37-38 at home.

Taylor Ward is enjoying the best season of his career. The veteran slugger has 34 big flies with 101 RBIs and a .785 OPS. Ward has six RBIs this month. Zach Neto is on the IL. He has 62 RBIs. Luis Rengifo has amassed 10 RBIs this month. The veteran has 43 RBIs and a .625 OPS on the year.Β  Mike Trout has been quiet against the Royals, posting zero RBIs and a weak .500 OPS. The star slugger has been good but not great, bashing 21 home runs with 59 RBIs on the season.Β  The Angels recently promoted one of their top prospects, Denzer Guzman. The rookie has two RBIs in eight games.

Los Angeles is scoring an average of 4.20 runs on this year, ranking them 25th. The pitching staff has reported a 4.86 ERA, ranking them 29th.

Royals vs. Angels Pick

Spread Pick for Royals vs. Angels

  • Los Angeles Angels +125 (5 units)

The Kansas City Royals are stumbling. They have dropped five of their past seven road games and are five games below .500 on the road on the season. The Los Angeles Angels have been poor on the road, but are a different team at home.Β  The Angels are just one game below .500 at the Big A and won their most recent home series.

Furthermore, these squads just met last month, and the Angels came away with two wins in three games, keeping K.C. to eight runs. Royals pitcher Cole Ragans is having a disappointing season, as seen in his poor 5.16 ERA, and he has also been plagued by injuries. Ragans is having a disastrous month, squandering 15 runs in his past 16.2 innings pitched. He surrendered five runs in his previous road outing.

Over/Under Pick for Royals vs. Angels

  • Over 9 (5 units)

I expect plenty of scoring in this one. Kansas City is scoring runs, posting 35 runs in its past five games, including a whopping 27 runs in the series against the Blue Jays. The Angels' pitching continues to be exposed. They have squandered five or more runs in seven of their last 10 games. Angels' pitcher Sam Aldegheri has pitched most of the season in the minor leagues. He has surrendered 17 runs in 19.1 career innings in the big leagues.

In addition, Los Angeles has been dangerous at the dish at home, scoring 27 runs in its past five home games. Ragans has struggled in his career against Los Angeles, posting a disastrous 6.12 ERA and a 0-3 record in 25 innings. The over is 5-2 in the Royals’ past seven road games.

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