Kansas City Royals vs. Los Angeles Angels Picks and Prediction, Thursday, September 25, 2025

By: Victor King Published 09/25/2025, 11:10 AM ET
Royals vs. Angels
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Kansas City Royals (79-78) vs. Los Angeles Angels (70-87)

The 2025 MLB betting action continues Thursday, September 25, with the Kansas City Royals taking on the Los Angeles Angels in the American League clash at Angel Stadium in Anaheim, CA, and we’ve got you covered with our Royals vs. Angels prediction.

Kansas City and Los Angeles close down their three-game series at Angel Stadium. The Royals beat the Angels 8-4 in the opener, while the middle game has been excluded from this preview. The bookies expect a tight battle in the closer, listing both teams at -108. Read more about this Royals vs. Angels prediction, one of our MLB picks for Thursday’s card. The first pitch at Angel Stadium is set at 9:38 PM ET.

The Royals hope for another strong display at the plate

The Kansas City Royals cruised past the Angels last Tuesday. The Royals outhit the Halos 15-5 on the night, while Cole Ragans punched out 10 across five innings of a two-run ball. Sam Long yielded two more runs in the bottom of the ninth.

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Kansas City has won five of its previous eight games overall. During that stretch, the Royals have scored 57 runs on a robust .322/.380/.534 slash line, while their bullpen has amassed a 4.00 ERA, 1.30 WHIP, and a .248 batting average against. Michael Lorenzen will be on the bump Thursday, and the 33-year-old right-hander is 6-11 with a 4.70 ERA and 1.35 WHIP in 25 starts and one relief appearance (136 innings pitched) this season. Last Friday, Lorenzen threw 7.2 innings in a 20-1 dismantling of the Blue Jays, allowing one earned run on three hits and three walks.

Lorenzen is 2-4 with a 3.89 ERA in six career starts and four relief appearances against the Angels. He met them earlier this month and tossed six innings of a two-run, four-hit ball in a 5-1 home loss against the Angels. The current Halos are 18-for-70 with a double and three home runs versus Lorenzen.

The Angels’ offense continues to struggle

The Los Angeles Angels mustered just five hits last Tuesday. Bryce Teodosio slugged a two-run homer, while Taylor Ward hit a solo home run, his 35th long ball of the season. Sam Aldegheri gave up three earned runs across 4.2 innings, and Brock Burke and Jose Urena combined for five more in relief.

The slumping Angels have dropped 10 of their previous 11 games overall. They’ve only scored 32 runs on an ugly .188/.232/.360 triple-slash during that stretch, while their bullpen has accounted for a 4.57 ERA, 1.41 WHIP, and a .235 batting average against. Mitch Farris will take the mound on Thursday night. The 24-year-old rookie left-hander carries a 1-2 record with a pedestrian 6.52 ERA and 1.45 WHIP in four starts (19.1 IP) in 2025. Last Friday, Farris surrendered seven runs (six earned) on eight hits and two walks across 4.1 innings in a 7-6 loss at the Rockies.

Farris made his MLB debut in a 5-1 road victory against the Royals on September 2, 2025. He took a win, allowing one earned run on three hits and two walks through five innings of work.

Royals vs. Angels Pick

Moneyline Pick for Royals vs. Angels

  • Kansas City Royals (5 units)

Mitch Farris pitched well in his major league debut. However, Farris has allowed a whopping 12 runs (11 earned) on 13 hits and six walks across 8.1 innings of work. Interestingly, Farris hasn’t pitched in Triple-A. Through 116 innings of work in Double-A this season, Farris has recorded a 4.27 ERA and 1.47 WHIP.

The Royals are more dangerous when hitting the righties, but I expect them to get to Farris this time around. Michael Lorenzen will look to build on his strong performance against the Blue Jays, and I will take the Royals in this game.

Keep in mind that there’s nothing to play for, as both teams have been eliminated from playoff contention.

Over/Under Pick for Royals vs. Angels

  • ·Over 9.0 (5 units)

The total is a tricky wager for a couple of reasons. First, these two bullpens have been shaky lately. Second, the Angels’ lineup leans on a long ball and has struggled over the last 10 days. I mentioned the Angels’ awful batting average and on-base percentage.

The Angels have scored more than three runs just twice in their previous 10 games overall. On the other hand, they’ve allowed at least five runs in seven of their past nine contests.

I don’t trust Mitch Farris, so give me the over on the total. The bullpens should help me, too.

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