Los Angeles Angels vs. Colorado Rockies Picks and Prediction for Friday, September 19, 2025
Use Code WWWC Los Angeles Angels (69-83) vs. Colorado Rockies (41-111)
The MLB betting action continues Friday, September 19, 2025, with the Los Angeles Angels taking on the Colorado Rockies in the interleague showdown at Coors Field in Denver, Colorado, and we’ve got the Angels vs. Rockies prediction to get you covered.
It’s the opener of a three-game regular-season series between Los Angeles and Colorado. Last year, the Rockies took two out of three from the Angels in Anaheim.
Now, let’s take a closer look at this Angels vs. Rockies prediction, one of our MLB picks for Friday’s slate. The first pitch at Coors Field is set at 8:10 PM ET.
The Angels continue their 10-game road trip
Thursday’s games have been excluded from the analysis, and the 69-83 Los Angeles Angels visited the Milwaukee Brewers on Thursday night, hoping to snap a six-game losing streak. After getting swept by the Seattle Mariners in a four-game series, the Angels have dropped consecutive games in Milwaukee by an identical 9-2 result.
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During their six-game losing streak, the Angels have only scored 16 runs on a hideous .167/.202/.333 slash line. Their bullpen has thrown 29 innings while posting a 4.03 ERA, 1.24 WHIP, and a .202 batting average against.
Mitch Farris is projected to take the mound at Coors Field on Friday night. The 24-year-old rookie left-hander carries a 1-1 record with a 4.80 ERA and 1.20 WHIP in three starts (15 innings pitched) in 2025. Last Saturday, Farris pitched four innings in a 5-3 loss at the Mariners, allowing five earned runs on five hits and four walks.
The Rockies cannot wait for the season to end
The 41-111 Colorado Rockies hosted the Miami Marlins on Thursday afternoon, looking to avoid their fifth straight loss. After a couple of road losses against the San Diego Padres, 11-3 and 9-6, the Rockies have lost consecutive games against the Marlins, 6-5 and 8-4.
The Rockies have only won one of their previous 11 games overall. During that stretch, the Rocks have scored 34 runs on a horrendous .209/.260/.322 triple-slash, while their bullpen has compiled a 5.40 ERA, 1.56 WHIP, and a .295 batting average against across 46.2 innings of work.
At the time of writing, it was unknown who would get the starting call for Colorado on Friday night. It is Antonio Senzatela’s turn, and the 30-year-old right-hander has been terrible so far this season, posting a 4-15 record with a 6.84 ERA and 1.85 WHIP in 23 starts and five relief appearances (126.1 IP).
Angels vs. Rockies Pick
Moneyline Pick for Angels vs. Rockies
- Los Angeles Angels (4 units)
Last Saturday, Antonio Senzatela pitched three innings of a four-run ball in relief and didn’t factor in the decision, as the Padres routed the Rockies 11-3. Bradley Blalock got the nod and took a loss, yielding five earned runs across three innings of work. Blalock is now 1-5 with an ugly 9.00 ERA and 1.82 WHIP in 10 starts and two relief appearances (50 IP) in 2025.
One of these two guys should get the starting call on Friday, and whoever takes the mound, I will go with the Angels. It’s hard to trust the Rockies bullpen, which has struggled for most of the season, and Colorado’s lineup has been an absolute disaster over the last couple of weeks.
The Rockies are having a historically bad season. However, keep in mind that there is nothing to play in this game. Hopefully, the Angels’ pitching will make a difference.
Over/Under Pick for Angels vs. Rockies
- Over (4 units)
Both teams have struggled a lot at the plate lately. The Angels will send a lefty to the mound, and the Rockies have recorded a .639 OPS and 75 wRC+ against the lefties over the past 10 days. During that span, the Angels have accounted for a 54 wRC+ against the southpaws and a 66 wRC+ versus the righties.
Hereof, I will hold my nose and take the under. Frankly, betting on the under at Coors Field is rarely a good idea, though four of the Rockies’ previous 10 home games have gone under the total.
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