Los Angeles Angels vs Houston Astros Picks and Prediction for Sunday March 29 2026

By: Dylan Hellebrand Published 03/29/2026, 05:40 AM ET
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On Sunday, the Los Angeles Angels (2–0) will take on the Houston Astros (0–2) at Daikin Park in Houston, Texas. The Angels have opened the season strong, and if they also win Saturday, they’ll head into Sunday with a chance to take the series in the very first set of the season for both teams. Get involved in the action with our free MLB picks.

Los Angeles vs. Houston Game Information

  • March 29, 2026
  • 2:10pm EST
  • Daikin Park
  • MLB.TV/FanDuel Sports Network West/Space City Home Network

Houston Form & Recent Results

Houston heads into this matchup knowing it’s already in an early-season hole, and it’ll be trying hard to avoid opening the season with three straight losses if things go south on Saturday. In Friday’s 6–2 loss to the Angels, Yordan Alvarez provided one of the few bright spots for the Astros at the plate, finishing 1-for-5 but making it count with a home run. He also crossed the plate once and drove in a run, giving Houston a brief spark in a game where the offense never fully got rolling.

Last season, the Astros had plenty of production from their key bats. Christian Walker paced the team in power with 27 home runs and also led the way in run production, finishing with 88 RBIs. Jose Altuve wasn’t far behind in the home run department either, launching 26 of his own. Meanwhile, Jeremy Peña set the tone in terms of pure hitting, leading Houston with a strong .304 batting average. Still, this season hasn’t started the way the Astros envisioned, and they’re now trying to avoid dropping a series to an Angels team many expect to sit near the bottom of the American League. To try to steady things, Houston is set to hand the ball to Tatsuya Imai for Sunday’s game.

Los Angeles Form & Recent Results

Los Angeles comes into this game with plenty of early-season momentum, having won their first two games of the season heading into Saturday’s third game of the series. They continued that strong start on Friday with a 6–2 win over Houston, powered by a big night from Josh Lowe. Lowe finished 2-for-4 at the plate, launched a home run, scored once, and drove in three runs, giving the Angels the kind of timely offense they needed to get ahead early in the season. It’s also worth remembering what this lineup looked like last year: Jo Adell paced Los Angeles in home runs with 37, while Taylor Ward, now with the Baltimore Orioles, was right behind him with 36. Ward also served as the team’s top run producer, leading the Angels with 103 RBIs.

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From a broader perspective, this start already stands out historically for the franchise, since the Angels haven’t opened a season 2–0 since 2007. That’s a notable change of pace for a team many preseason projections had pegged near the bottom of the AL West standings. Now, with a chance to take their first series of the season against a tough Houston club, Los Angeles will try to keep proving the critics wrong and keep the good vibes rolling. Nolan Schanuel, who led the team with a .264 batting average last year, will be one of the key table-setters again, and the Angels will hand the ball to Jack Kochanowicz as they look to stay unbeaten and finish the job in this series on Sunday.

Key Stats

  • Los Angeles’ Zach Neto on Friday: 2-for-5, 2 runs, 1 home run, 1 RBI
  • Houston’s Jeremy Pena on Friday: 2-for-5, 1 run

Betting Odds & Market Overview:

  • N/A

Los Angeles vs. Houston Picks and Prediction

The Angels have opened the season with an unexpected 2–0 start, something they haven’t done in 19 years. Meanwhile, the Astros are already trying to steady themselves; if they drop Saturday’s game, they’ll start the season by losing the series.

Through the first two games, Houston’s lineup hasn’t been able to crack the Angels’ pitching and defense, but it’s hard to imagine that staying quiet for long, so they’ll be looking to finally break through with a stronger showing. On the other side, the Angels will try to keep proving people wrong by riding the momentum and continuing to swing the bats well as the season gets underway. Final Score Prediction, Houston Astros win 4-0.

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